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Radioimmunotherapy shows promise for HIV infection and viral cancers

Scientists at Albert Einstein College of Medicine of Yeshiva University have piggybacked antibodies onto radioactive payloads to deliver doses of radiation that selectively target and destroy microbial and HIV-infected cells.

16 Feb 2009

Obesity, a major risk factor for diabetes and other ills, targeted by study

Waistlines are expanding at such an alarming rate across the globe that, if trends hold, almost 58 percent of the world's population will be overweight or obese by 2030, according to researchers at the Tulane School of Public Health and Tropical Medicine.

16 Feb 2009

Jumping genes play significant role in gene regulatory networks

Research performed in the Center for Biomolecular Science & Engineering (CBSE) at the University of California, Santa Cruz, suggests that mobile repetitive elements--also known as transposons or "jumping genes"--do indeed affect the evolution of gene regulatory networks.

16 Feb 2009

Neural wiring hints at nervous system gene limits

Genetics may play a surprisingly small role in determining the precise wiring of the mammalian nervous system, according to painstaking mapping of every neuron projecting to a small muscle mice use to move their ears.

16 Feb 2009

Nanoscopic changes to pancreatic cells reveal cancer

A team of researchers in Chicago has developed a way to examine cell biopsies and detect never-before-seen signs of early-stage pancreatic cancer, according to a new paper in the Optical Society (OSA) journal Optics Letters.

16 Feb 2009

Mouse model mimics hyperglycemia, aids in diabetes research

UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die.

16 Feb 2009

Molecular motors in cells work together in close coordination

Even within cells, the left hand knows what the right hand is doing.

16 Feb 2009

Molecules self-assemble to provide new therapeutic treatments

Researchers in the laboratory of Samuel I. Stupp at Northwestern University have an interesting approach for tackling some major health problems: gather raw materials and then let them self-assemble into structures that can address a multitude of medical needs.

16 Feb 2009

Are insulin pens safe for blind people?

Ann Williams, a National Institute of Health-supported postdoctoral fellow at Case Western Reserve University, understands what it means to live with diabetes.

16 Feb 2009

Higher blood sugar levels linked to lower brain function in diabetics

Results of a recent study conducted by researchers at Wake Forest University Baptist Medical Center and colleagues show that cognitive functioning abilities drop as average blood sugar levels rise in people with type 2 diabetes.

16 Feb 2009

Funding injection for spinal injury research

Three of the projects are ambitious multi-centred trials involving an array of different interventions including electrically-stimulated exercises for the paralysed muscles and computer-based training for the quadriplegic hand.

16 Feb 2009

First immune danger receptor' found

Cancer Research UK scientists have found the first biological receptor that alerts the immune system to 'dangerous' or abnormal cell death, according to research published in Nature.

16 Feb 2009

Common gene variants increase risk of hypertension, may lead to new therapies

A new study has identified the first common gene variants associated with an increased incidence of hypertension - a significant risk factor for heart attack, stroke and kidney failure.

16 Feb 2009

Artificial cells, simple model for complex structure

A simple, chemical materials model may lead to a better understanding of the structure and organization of the cell according to a Penn State researcher.

16 Feb 2009

Novel gene silencing platform

A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches.

16 Feb 2009

New approaches to prevent transplant rejection

To prevent the rejection of newly transplanted organs and cells, patients must take medicines that weaken their entire immune systems.

15 Feb 2009

True or false? How our brain processes negative statements

Every day we are confronted with positive and negative statements.

15 Feb 2009

Study reveals high level of adverse drug reactions in hospitals

In a study of more than 3,000 patients, researchers at the University of Liverpool have found that one in seven admitted to hospital experience adverse drug reactions to medical treatment.

15 Feb 2009

Statistical analysis could yield new drug target for multiple sclerosis

An elaborate statistical analysis of genes from more than 7,000 individuals has identified an amino acid that appears to be a major risk factor for multiple sclerosis, a devastating autoimmune disorder that afflicts 2.5 million people worldwide.

15 Feb 2009

Smokers put loved ones at risk of heart attacks

Researchers at University College London and St George's, University of London measured recent exposure to tobacco smoke in non-smoking middle-aged men taking part in the British Regional Heart Study by measuring the levels of cotinine - a compound carried in the blood - at two time points 20 years apart.

15 Feb 2009