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Jefferson scientists discover way to immunize mice against metastatic disease

Taking advantage of the fact that the intestines have a separate immune system from the rest of the body, scientists at the Kimmel Cancer Center at Jefferson in Philadelphia have found a way to immunize mice against the development of metastatic disease.

24 Jun 2008

Epigenetic changes occur over a person's lifetime

Researchers at Johns Hopkins have found that epigenetic marks on DNA-chemical marks other than the DNA sequence-do indeed change over a person's lifetime, and that the degree of change is similar among family members.

24 Jun 2008

Pitt awarded $2.5 million to model how the brain and immune system function in response to illness, infection

In an effort to promote the application of mathematics to medical treatment, researchers in the University of Pittsburgh's Department of Mathematics will undertake a $2.5 million project to create models of how the brain and immune system function and change over time in response to certain illnesses, infections, and treatment.

24 Jun 2008

New discovery could lead to new treatments for Alzheimer's

Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively "puts the brakes" on the dementia that comes with Alzheimer's disease (AD). When the brakes fail, dementia results.

24 Jun 2008

Blue curing light for tumors

A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say.

24 Jun 2008

Binge drinking in the UK: A social network phenomenon

The rise in binge drinking in the young is a "fashion phenomenon" where drinkers are copying their associates' behaviour, new research has shown.

24 Jun 2008

UT Southwestern plastic surgeons identify hidden facial cheek fat compartments that are key to youthful appearance

Rejuvenating newly identified fat compartments in the facial cheeks can help reduce the hollowed look of the face as it ages, according to new research by plastic surgeons at UT Southwestern Medical Center.

24 Jun 2008

Alzheimer's and Parkinson's under the microscope

A detailed discussion by top researches in the field into current Alzheimer's and Parkinson's research features as article of the month in the prestigious journal, Nature Reviews Neuroscience.

24 Jun 2008

Quantum dots stop RNA interference in living cells

More than 15 years ago scientists discovered a way to stop a particular gene in its tracks. The Nobel Prize-winning finding holds tantalizing promise for medical science, but so far it has been difficult to apply the technique, known as RNA interference, in living cells.

24 Jun 2008

Discovery of an important factor in the development of B-cell lymphomas

Researchers at National Jewish Medical and Research Center have discovered an important factor in the development of B-cell lymphomas, one of the fastest growing forms of cancer. The B-cell receptor on the surface of B cells can cooperate with the MYC oncogene to accelerate the development of lymphomas.

24 Jun 2008

Guidelines for reporting health research have little funding

Although reporting guidelines can improve the accuracy and reliability of research reports, there is little funding available for developing such guidelines, according to a new survey published in the open access journal PLoS Medicine this week.

24 Jun 2008

New details on how low blood flow promotes vascular disease

Researchers have found the first direct proof that a key protein drives the clogging of arteries in two ways, and that lowering levels of it opens them up, according to study results published in the June edition of the journal Circulation.

24 Jun 2008

Hunger hormone ghrelin increases during stress, may have antidepressant effect

New research at UT Southwestern Medical Center may explain why some people who are stressed or depressed overeat.

24 Jun 2008

Researchers create molecule that nudges nerve stem cells to mature

Inspired by a chance discovery during another experiment, researchers at UT Southwestern Medical Center have created a small molecule that stimulates nerve stem cells to begin maturing into nerve cells in culture.

24 Jun 2008

Hedgehog signaling is critical for maintenance of the adult coronary vasculature

A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis.

23 Jun 2008

New, previously unrecognized source of heart stem cells discovered

Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells. These stem cells, located in the surface of the heart, or epicardium, advance the hope of being able to regenerate injured heart tissue.

23 Jun 2008

Could Gleevec help stroke victims?

For over a decade, the drug called tPA has proven its worth as the most effective emergency treatment for the most common kind of stroke. But its promise is blemished by two facts: tPA can cause dangerous bleeding in the brain, and its brain-saving power fades fast after the third hour of a stroke.

23 Jun 2008

New white wine as good for you as red!

Red wine is favoured by many health conscious tipplers because it contains higher levels of polyphenols - antioxidants which lower cholesterol and are thought to help prevent cancer.

23 Jun 2008

Hormone could hold the key to staying slim

Researchers in the United states are suggesting that the key to maintaining a healthy weight may be related to a hormone produced by the body.

23 Jun 2008

Discovery of possible new way to block inflammation in autoimmune disease

Researchers from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), have identified a promising new target for autoimmune disease treatment - a cell-surface receptor called DR3.

23 Jun 2008