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Substance found in evening primrose oil inhibits breast cancer gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

3 Nov 2005

Fundamental insight about protein evolution

While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution: different species make use of similar sets of proteins in different ways.

3 Nov 2005

New targeted cancer drug delivery system

Prostate, breast and other cancer patients may be offered a new, stauncher targeted drug delivery system to treat their diseases in the next decade.

3 Nov 2005

New method to find deadly malaria parasite

Researchers at UCSD have discovered that the single-cell parasite responsible for an estimated 1 million deaths per year worldwide from malaria has protein "wiring" that differs markedly from the cellular circuitry of other higher organisms

3 Nov 2005

Shortness of breath can be a serious cardiac symptom

Now, researchers at Cedars-Sinai Medical Center have found that patients with shortness of breath can have a higher risk of dying from cardiac disease than patients without symptoms, and even than patients with typical cardiac pain.

3 Nov 2005

Targeted drug delivery now possible using nanoparticle-apatamer conjugates

Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates.

3 Nov 2005

Nearly one-fourth of all dialysis patients have a close relative on dialysis

Researchers at Wake Forest University Baptist Medical Center, and others, report in the current online edition of the American Journal of Nephrology. The researchers suggest screening other relatives for undetected kidney disease.

3 Nov 2005

New findings on bacterial vaginosis

Despite being one of the most common infections among women, scientists and doctors know little about the causes of bacterial vaginosis (BV), a usually benign disease that is also linked to serious health problems including pelvic inflammatory disease

3 Nov 2005

Colon cancer and fruit and vegetable products

The amounts of health promoting compounds in fruit and vegetable products vary so much that the possible beneficial health effects from these products is far from optimal.

3 Nov 2005

Combination of radiotherapy and a drug named S247 as a cure for cancer

Does a combination of radiation therapy and the inhibition of integrins (key molecules in angiogenesis) improve the chance of cure in cancer?

3 Nov 2005

Important breakthrough in developing the drugs of the future

Their work on targeting individual genes for more effective and cheaper drug testing opens the way to treatments for a huge range of diseases including diabetes and atherosclerosis, which leads to strokes and heart attacks.

3 Nov 2005

Cancer Vaccine - Synthetically generated glycopeptides from tumor cells can stimulate the formation of specific antibodies

Tumor cells and healthy somatic cells differ in the structures on their surfaces. In principle, it should thus be possible to develop a vaccine that causes a patient’s immune system to form antibodies that attack and destroy tumor cells while sparing healthy cells.

3 Nov 2005

New chemo combo means longer life for pancreatic cancer patients

Pancreatic cancer is one of the most difficult cancers to treat, and has an overall one-year survival rate of only 13%.

3 Nov 2005

Feeling puffed? could be a sign of serious heart problem

Most people know that chest pain can indicate the presence of heart disease, but less well known apparently is that shortness of breath can also be a symptom of serious cardiac problems

3 Nov 2005

Fertile women most attractive to men

According to researchers at the University of St Andrews, Scotland, women with high levels of the sex hormone oestrogen have prettier faces.

2 Nov 2005

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) in Paris have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates.

1 Nov 2005

Protein called CHIP helps untangle protein misfolding in brain disease

Keeping the body and mind healthy depends on keeping cells healthy and functioning. This means that cells need a very robust quality-control system to repair or remove damaged or misshapen proteins. Protein handling is especially important in neurons because damage or death of brain cells causes neurological disease.

1 Nov 2005

Vaginal gel shown to protect female monkeys against an HIV-like virus

Research with female monkeys at the Tulane National Primate Research Center has for the first time shown that three different anti-viral agents in a vaginal gel protect the animals against an HIV-like virus.

1 Nov 2005

Silent reflux may be the cause of sleep disturbances in patients with unexplained sleep disorders

Patients with sleep complaints but no heartburn symptoms suffered episodes of nighttime acid reflux according to research presented at the 70th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2005

Researchers determine how Tsg101 gene controls cellular growth

Researchers at Emory University School of Medicine and their colleagues have discovered a genetic mechanism that controls cellular growth in the fruit fly Drosophila melanogaster, and believe it likely that a similar system may be at work in normal and cancerous human cells.

1 Nov 2005