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Intravenous lidocaine and oral derivatives relieve pain from damage to the nervous system

Lidocaine and similar local anesthetics are effective for treating pain that emanates from damaged nerves, according to a systematic review of current evidence.

23 Oct 2005

Nitric oxide may help sickle cell patients

Inhaling a small dose of nitric oxide gas may one day help sickle cell patients avoid pain crises and live healthier lives, researchers say.

23 Oct 2005

Scientists discover molecular structure related to cell growth and cancer

Researchers discovered a special type of molecular structure that helps keep genes properly turned off until the structure is ejected from those genes in a regulated manner to help turn the genes on.

23 Oct 2005

Gene found only in men is altered by a chemical process, which is in turn linked to aggressive forms of melanoma

New scientific evidence that may shed light on why men are more likely than women to develop aggressive forms of skin cancer has been published in Carcinogenesis.

23 Oct 2005

Method to count the absolute number of individual protein molecules inside a living cell

Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively.

20 Oct 2005

Deep brain stimulation can lower blood pressure

The possibility of a patient lowering their blood pressure at the flick of a switch has been raised by research led by Oxford University, which shows that stimulating parts of the brain with electrodes can change a patient’s blood pressure.

20 Oct 2005

Diabetes drugs may also prevent nerve degeneration caused by Alzheimer's disease

Recent research has shown a surprising link between Alzheimer’s and diabetes, two of the major health challenges facing society today. According to Dr Holscher modern lifestyle promotes the development of type 2 diabetes, which in turn could drastically increase the number of people to develop Alzheimer’s disease as people with type 2 diabetes are much more likely to develop the disease than healthy people of the same age.

20 Oct 2005

Better knowledge of how the mechanism explaining alcohol addiction works

Alcohol, like any other substance that reinforces behaviour, such as another drug of abuse or even food, has a certain capacity to enhance social memory, that is, the ability to remember other individuals. If a mouse is administered alcohol immediately after being introduced to another animal of its own kind, the former will recognise the latter sooner.

20 Oct 2005

Researchers discover the presence of functional ion channels in human embryonic stem cells

These ion channels act like electrical wires and permit ESCs, versatile cells that possess the unique ability to become all cell types of the body, to conduct and pass along electric currents.

20 Oct 2005

Menin is a key player in the development of some forms of acute leukemia

Tumor-suppressor proteins work to inhibit tumor growth in our bodies and when they win, they spare us a battle with cancer. But one such protein, menin, appears to have a split personality.

20 Oct 2005

Researchers learn to rapidly rebuild immunity in immune-suppressed cancer patients

Patients with multiple myeloma suffer from a malignant proliferation of plasma cells in their bone marrow. The standard treatment for this form of cancer is high-dose chemotherapy and transplantation of one's own blood-producing adult stem cells; however, this aggressive treatment wipes out the mature immune-system cells of patients – leaving them vulnerable to infection.

20 Oct 2005

Discovery of a new kind of messenger RNA molecule

Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection.

20 Oct 2005

Spliceosome crucial for processing non-coding RNA

The discovery in 1977 that the coding regions of a gene could appear in separate segments along the DNA won the 1993 Nobel Prize in Physiology or Medicine for Richard J. Roberts and Phillip A. Sharp. The active segments of a gene were termed exons, separated from each other within the gene by inactive introns.

20 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

Alzheimer disease and the blood brain barrier

Increased production of the amyloid-beta (Abeta) peptide can lead to Abeta aggregation and buildup in the brain and rare familial forms of early onset Alzheimer disease (AD).

20 Oct 2005

Identification of a factor in human milk that can block HIV-1 transmission

Mother to child transmission of HIV accounts for a large proportion of HIV infections in children, with many infected as a result of breastfeeding, which requires transfer of the virus across mucosal barriers. DC-SIGN, a DC lectin receptor, interacts with HIV and is found at high expression levels in tonsillar tissue.

20 Oct 2005

Retiring early is not linked to longer life

There is a widespread perception that early retirement is associated with longer life expectancy and later retirement is associated with early death. But no consensus has been reached on the effect of early retirement on survival.

20 Oct 2005

U.S. health inequalities cause 84,000 extra deaths every year

Research estimates that health inequalities between white and black Americans cause 84,000 extra deaths every year – equating to a virtual hurricane Katrina every week, says an editorial in this week’s British Medical Journal.

20 Oct 2005

26% of HIV-infected individuals reported that they felt discriminated against by physicians

Research published in the Journal of General Internal Medicine reveals that 26% of HIV-infected individuals reported that they felt discriminated against by physicians and other health care providers. Despite demographic variations, all subgroups reported discrimination of some type.

20 Oct 2005

Screening test would give hope to childless couples

According to new research thousands of childless British couples could greatly improve their chances of having a baby if a test that weeds out faulty embryos were carried out.

20 Oct 2005