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Research reveals possible mechanisms for the treatment of cocaine addiction

Researchers are now understanding in greater detail the molecular machinery underlying the short-term brain changes that produce the high of cocaine, as well as the longer-term changes behind addiction. Their findings offer hope for targeted drugs that can short-circuit that addiction machinery.

19 Oct 2005

Identification of a single chromosome region linked to specific language impairment

Researchers at the University of Toronto (U of T), Capital Health's Stollery Children's Hospital in Edmonton, Toronto's Hospital for Sick Children and their international collaborators have discovered a genetic abnormality that causes a type of language impairment in children

19 Oct 2005

A DNA-based vaccine could be a potent weapon against bird flu

Researchers scrambling to combat a virulent form of bird flu that could mutate into a form easily spread among humans should consider developing vaccines based on DNA, according to British biochemical engineers.

19 Oct 2005

South Korea opens controversial international stem cell bank

South Korea has opened a bank in Seoul that will create and supply new lines of embryonic stem cells for research around the world.

19 Oct 2005

Fertility treatment most successful in summer

When it comes to considering fertility treatment, scientists say that women who have the treatment during the summer are twice as likely to become pregnant as those who have it in the winter.

19 Oct 2005

Surgery to treat obesity far more risky for men

Researchers say that using stomach-shrinking surgery to treat severe obesity is riskier than previously thought for men, the elderly and people with conditions such as hypertension.

19 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

People who carry a mutation in the melanoma susceptibility gene CDKN2A have a much lower risk of melanoma

In addition, most familial clusters of melanoma occur in families without identifiable mutations in this gene, according to a new study that appears in the October 19 issue of the Journal of the National Cancer Institute.

18 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

Newly discovered role of MECP2 gene in Rett Syndrome

Huda Zoghbi, of Baylor College of Medicine and the Howard Hughes Medical Institute and Juan Young, also of Baylor and colleagues report in the online Early Edition of the Proceedings of the National Academy of Science, posted the week of October 17, 2005, that the Rett Syndrome gene, MECP2, regulates RNA splicing.

18 Oct 2005

Atypical antipsychotic drugs slightly increase risk for death when used in people with dementia

Atypical antipsychotic drugs seem to confer a small increased risk for death when used in people with dementia, concludes a team of researchers from the Keck School of Medicine of the University of Southern California in a meta-analysis of 15 clinical trials published in the October 19 issue of the JAMA: The Journal of the American Medical Association.

18 Oct 2005

Short course of rTMS can increase finger sensitivity

Repetitive transcranial magnetic stimulation (rTMS) has emerged as an intriguing technique for exploring brain function, and a promising, though still unproven, form of therapy.

18 Oct 2005

No evidence of a "safe" threshold with environmental toxins

Four of the most widespread environmental toxins - lead, trihalomethanes (found in drinking water), ionizing radiation from indoor radon gas, and tobacco smoke - can cause serious damage to health even at very low levels, say researchers in the open access journal PLoS Medicine.

18 Oct 2005

Brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury

A study of patients who have difficulty paying attention to the left side of their environment has provided some of the first direct evidence that brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury.

17 Oct 2005

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

A way to detect fragments of broken brain cells that leak into the bloodstream may help doctors more quickly and precisely treat people with severe head injuries or brain diseases, say researchers at the University of Florida's McKnight Brain Institute.

17 Oct 2005

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

By using a chemical analysis method developed for air-pollution testing, UCI chemists and pediatricians have found that people with cystic fibrosis exhale higher concentrations of sulfur compounds from their lungs than do people who don't have the disease.

17 Oct 2005

Researchers identify biomarker that indicates a more agressive form of prostate cancer

Staging factors for prostate cancer such as PSA and the Gleason score are extremely useful in predicting prostate cancer outcome," explained Pollack. "However, new biomarkers hold promise in strengthening our ability to predict response to treatment. By identifying the more virulent forms of prostate cancer, we may be able to tailor treatment or develop therapies to target the abnormalities identified."

17 Oct 2005

Hormone responsible for types of high blood pressure could also cause preeclampsia

Researchers at the University of Cincinnati (UC) Academic Health Center have found evidence of a hormone they say is responsible for certain types of high blood pressure (hypertension), and could also cause preeclampsia, a potentially dangerous condition that occurs during pregnancy.

17 Oct 2005

New genetic discovery may help explain why some people develop high blood pressure and others don't

It also gives new insight into how the kidneys govern the balance of salt in the body, a crucial task for regulating blood pressure. And, it reveals how a gene already linked to behavior and mental health can play a role in the body, as well as the brain.

17 Oct 2005

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

Medical Research News

Research reveals possible mechanisms for the treatment of cocaine addiction

Identification of a single chromosome region linked to specific language impairment

A DNA-based vaccine could be a potent weapon against bird flu

South Korea opens controversial international stem cell bank

Fertility treatment most successful in summer

Surgery to treat obesity far more risky for men

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

People who carry a mutation in the melanoma susceptibility gene CDKN2A have a much lower risk of melanoma

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Newly discovered role of MECP2 gene in Rett Syndrome

Atypical antipsychotic drugs slightly increase risk for death when used in people with dementia

Short course of rTMS can increase finger sensitivity

No evidence of a "safe" threshold with environmental toxins

Brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

Researchers identify biomarker that indicates a more agressive form of prostate cancer

Hormone responsible for types of high blood pressure could also cause preeclampsia

New genetic discovery may help explain why some people develop high blood pressure and others don't

Significant step forward in the genome era

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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