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Epigenetic silencing of BEND4 unveils new path for PDAC treatment

A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 as a potential synthetic lethal marker for enhancing the efficacy of ATM inhibitors in pancreatic cancer treatment.

7 Nov 2024

Electric fans ease heart strain for older adults in humid heat

New collaborative research from the University of Sydney and the Montreal Heart Institute has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US.

6 Nov 2024

Assessing recurrence risk with ctDNA-based MRD detection in NSCLC patients

In operable non-small cell lung cancer (NSCLC), molecular residual disease (MRD) detection via circulating tumor DNA (ctDNA) has emerged as a promising approach to identify individuals at high risk of disease recurrence and potentially guide adjuvant therapy decisions.

6 Nov 2024

Mount Sinai researchers uncover key process in memory integration

Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience.

6 Nov 2024

Understanding the role of neuroimmune cells in brain health and disease

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

6 Nov 2024

Cachexia diagnosis criteria affect cancer patient survival rates

Maintaining good health and well-being is crucial for how well patients respond to cancer treatments. Unfortunately, cachexia, or involuntary weight loss, is a major concern for many individuals with advanced cancer.

6 Nov 2024

Review: The multifaceted roles of bilirubin in liver health and disease

Bilirubin, the byproduct of hemoprotein breakdown, particularly hemoglobin, is a critical marker in diagnosing, prognosing, and managing liver diseases.

6 Nov 2024

New wearable device provides immersive sensory feedback on the skin

A Northwestern University-led team of engineers has developed a new type of wearable device that stimulates skin to deliver various complex sensations.

6 Nov 2024

Research sheds light on how fecal transplants improve gut health

In a novel study that identified male chromosome genetic material in the intestines of female patients undergoing fecal transplants, researchers at Johns Hopkins Medicine say they have significantly expanded scientific understanding of how some of these transplants may succeed and work.

6 Nov 2024

DEEPscope breaks barriers in deep-tissue brain imaging

Researchers at Cornell have unveiled an advanced imaging technology capable of unprecedented deep and wide-field visualization of brain activity at single-cell resolution.

6 Nov 2024

Stanford researchers unveil the key role of extrachromosomal DNA in cancer

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles -; until recently dismissed as inconsequential -; are major drivers of many types of human cancers.

6 Nov 2024

Rice bioengineers uncover why IL-12 immunotherapy loses effectiveness

A team of Rice University bioengineers has developed a mathematical model that clarifies why interleukin-12 (IL-12) ⎯ a potent immune-boosting protein that holds promise for cancer treatment ⎯ loses effectiveness over time when used as an immunotherapeutic.

6 Nov 2024