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Study links neurotensin deficiency to ovulatory dysfunction in PCOS

Polycystic ovary syndrome (PCOS) represents a significant health concern for women of reproductive age, manifesting as a complex endocrine disorder with diverse clinical presentations.

3 Apr 2025

Bach2 protein identified as key regulator in atopic dermatitis

Atopic dermatitis is an allergy affecting approximately 10% of the Japanese population, with symptoms closely related to social stress.

3 Apr 2025

Targeting a key protein outside of the brain could help manage Parkinson's-related heart issues

Parkinson's doesn't just affect movement and the brain - it may also impact the heart, according to new research from the University of Surrey. Scientists from Surrey's School of Veterinary Medicine suggest that targeting a key protein outside of the brain could help manage Parkinson's-related heart issues.

3 Apr 2025

Breakthrough research identifies small peptide for psoriasis treatment

Birmingham scientists have shown that a sequence of just three amino acids may reduce the severity of psoriasis, when applied topically in an emollient cream.

3 Apr 2025

Gut bacteria may reduce the effectiveness of common medications

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

3 Apr 2025

Switching to a Western diet triggers inflammation and weakens immunity

A switch of just two weeks from a traditional African diet to a Western diet causes inflammation, reduces the immune response to pathogens, and activates processes associated with lifestyle diseases.

3 Apr 2025

Dutch dietary guidelines could dramatically cut chronic disease rates by 2050

Researchers investigate the impact of current Dutch dietary guidelines on non-communicable disease rates.

3 Apr 2025

Addressing low lung cancer screening rates through awareness and access

Lung cancer screening has the potential to catch lung cancer early and save lives-but only if people get screened. Although lung cancer screening is recommended in the U.S. for certain individuals with a history of smoking, only 18% of eligible individuals in the U.S. get screened.

3 Apr 2025

New cystic fibrosis newborn screening guidelines aim for equitable detection

The United States Cystic Fibrosis Foundation released the first guideline on newborn screening for cystic fibrosis (CF), in order to improve timely detection of CF in infants from all racial and ethnic backgrounds.

3 Apr 2025

Mouse and organoid models reveal FGFR2's role in pancreatic cancer aggression and interception

Pancreatic cancer is projected to become the second-deadliest cancer by 2030. By the time it's diagnosed, it's often difficult to treat. So, for both individual patients and the general population, fighting pancreatic cancer can feel like a race against time. Cold Spring Harbor Laboratory (CSHL) Professor and Cancer Center Director David Tuveson offers a telling analogy:

3 Apr 2025

Racial and age disparities in cervical artery dissection hospitalizations

Cervical artery dissection is a tear in an artery in the neck that provides blood flow to the brain. Such a tear can result in blood clots that cause stroke. A new study has found almost a five-fold increase in the number of U.S. hospitalizations for cervical artery dissection over a 15-year period.

3 Apr 2025

New structural and mechanistic understanding for cancer drug design

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and mechanistic understanding of the RAD52-DNA complex may help researchers develop new anti-cancer drugs.

3 Apr 2025

Wealth inequality drives higher US mortality compared to Europe

Comparing wealth and survival rates in the U.S. with those in Europe, researchers found that over a 10-year period, Americans across all wealth levels were more likely to die than their European counterparts.

3 Apr 2025

New research underscores the importance of broader health benefits in obesity care

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) suggests that weight loss program targeting a particular % weight loss are often failing, and that other factors should be considered including improvement of obesity-related complications, enhancing quality of life and overall physical and social functioning.

3 Apr 2025

Mount Sinai launches AI center to revolutionize small molecule drug discovery

The Icahn School of Medicine at Mount Sinai has launched the AI Small Molecule Drug Discovery Center, a bold endeavor that harnesses artificial intelligence (AI) to revolutionize drug development.

2 Apr 2025

Study reveals long-term decision-making deficits due to heavy alcohol use

For the first time researchers demonstrate in an animal how heavy alcohol use leads to long-term behavioral issues by damaging brain circuits critical for decision-making.

2 Apr 2025

New drug strategy targets Staphylococcus aureus toxin to treat pneumonia

Pneumonia caused by the bacterium Staphylococcus aureus is one of the most dangerous infections that can occur in hospital.

2 Apr 2025

Study investigates D-dimer testing in patients at higher risk of pulmonary embolism

A new study investigating D-dimer testing in patients who are at higher risk of pulmonary embolism (PE) has been published in the February issue of Academic Emergency Medicine (AEM), the peer-reviewed journal of the Society for Academic Emergency Medicine (SAEM).

2 Apr 2025

Study reveals hidden cardiovascular risks in real-world low-carb diets

Researchers examined a real-world low-carbohydrate high-fat (LCHF) diet population to assess links between nutrient intake and cardiovascular risk.

2 Apr 2025

Vegetarian diets may hinder healthy aging—unless diet quality is high

Older Chinese adults who followed vegetarian diets were less likely to reach age 80 in good health. However, this disadvantage disappeared for those consuming high-quality plant-based diets.

2 Apr 2025