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Aging of lung stem cells drives iron deficiency and reduces capacity for tumor formation

Aging induces iron deficiency, reducing stem cell function and tumor growth while enhancing ferroptosis resistance, revealing new cancer prevention strategies.

5 Dec 2024

Psilocybin therapy reduces depression in clinicians after pandemic frontline work

This study demonstrates psilocybin's effectiveness in reducing depression symptoms in healthcare workers, offering hope for pandemic-related mental health care.

5 Dec 2024

Liver conversion of fructose fuels cancer growth by supplying lipids for tumor proliferation

This research highlights the indirect role of fructose in cancer, revealing how liver metabolism enhances tumor growth through lipid-mediated mechanisms.

5 Dec 2024

Brief bursts of activity linked to heart health benefits for women

Research shows 3.4 minutes of daily VILPA is associated with a 45% reduction in major adverse cardiovascular events, highlighting sex differences in benefits.

5 Dec 2024

Replacing carbohydrates with protein and fat improves cholesterol profiles in type 2 diabetes

Research indicates that a carbohydrate-reduced, high-protein diet improves lipid metabolism and reduces liver fat in type 2 diabetes without weight loss.

5 Dec 2024

Chikungunya's health and economic impact likely underestimated

This study assesses chikungunya's health and economic impacts, revealing significant burdens on health systems and a global cost of approximately $49.9 billion.

5 Dec 2024

Coral-inspired bone graft could transform treatment for bone defects

Researchers at Swansea University have developed a revolutionary bone graft substitute inspired by coral which not only promotes faster healing but dissolves naturally in the body after the repair is complete.

5 Dec 2024

Creatine and resistance workouts combat sarcopenia

Combining creatine supplementation with resistance training boosts muscle strength, lean mass, and cognitive health in older adults, offering a safe and effective strategy against sarcopenia.

4 Dec 2024

Gut microbiome and brain evolution: New insights into energy allocation

Gut microbiota from primates with larger brains promotes glucose production and energy allocation for brain function, shedding light on metabolic strategies in evolution.

4 Dec 2024

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

Scientists identify β-hydroxybutyrate as a key regulator of protein solubility, offering a novel pathway to combat neurodegeneration in aging and Alzheimer’s disease.

4 Dec 2024

Alzheimer's genetic risk studies undermined by systemic biases

Recent research in Nature Genetics reveals pervasive biases in GWAX studies using parental history of Alzheimer’s, highlighting potential misdirection in genetic associations and disease risk predictions. A novel GSUB method identifies false signals stemming from confounding factors like survival bias and socioeconomic status.

4 Dec 2024

Glyphosate exposure linked to lasting brain inflammation

The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma.

4 Dec 2024

Immune cells play a key role in movement control and metabolic balance

Immune cells have a surprising and critical role in controlling movement and bridging neural activity with metabolic demands, concludes a groundbreaking study published in Nature by researchers at the University of Copenhagen and Imperial College London.

4 Dec 2024

Anti-obesity medications could help treat alcohol use disorders

Losing weight with anti-obesity medications (AOM) also resulted in decreased alcohol consumption for about half of the participants in a new study appearing in the current issue of JAMA Network Open.

4 Dec 2024

New insights into survival of breast cancer cells in the bone marrow

A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies.

4 Dec 2024

Common farming pesticides linked to rheumatoid arthritis

Exposure to specific pesticides is linked to increased rheumatoid arthritis risk, with notable dose-response trends for malathion and carbofuran among older licensed applicators in the Agricultural Health Study.

4 Dec 2024

Cancer cells block T-cell activation, but new therapies restore immune defenses

Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment. Restoring balance through PGE2 inhibition and IFN-I enhancement could renew immune defenses and improve immunotherapy outcomes.

4 Dec 2024

Aging reduces cancer risk by limiting cell regeneration

When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning.

4 Dec 2024

Scientists identify molecular mechanism behind idiopathic autism

Autism is a neurodevelopmental disorder characterized by difficulties in communication and social behavior. Approximately 20% of cases are linked to a specific genetic mutation, but the origin of the remaining 80%, known as idiopathic autism, remains a mystery.

4 Dec 2024