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New research identifies potential drug target to prevent kidney failure

A new study found that retinoic acid receptors (RARa) in the proximal tubules of the kidney play a crucial role in limiting the damaging effects of kidney injury that often lead to kidney failure.

9 Mar 2024

Scientists transform skin cells into functional eggs in mice

New research from Oregon Health & Science University describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos.

9 Mar 2024

New insights on the brain's emotional processing center

How much do our emotions depend on our senses? Does our brain and body react in the same way when we hear a fearful scream, see an eerie shadow, or smell a sinister odor? And does hearing an upbeat music or seeing a colorful landascape bring the same joy?

9 Mar 2024

Study unravels FOXO1's influence on blood vessel development

The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for tackling age-related disorders.

9 Mar 2024

Neuroscientists uncover brainwave dynamics in memory storage

In the space of just a few seconds, a person walking down a city block might check their phone, yawn, worry about making rent, and adjust their path to avoid a puddle.

8 Mar 2024

Study reveals blood markers to predict healthspan and aging trajectories

University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person's biological age -; how fast a person's cells and organs age regardless of their birthdate.

8 Mar 2024

Single neurons encode vital physiological signals from the heart and lungs

The body self-regulates in a process known as homeostasis, and the brain is responsible for this as it is constantly monitoring all of the body's vital signals.

8 Mar 2024

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine.

8 Mar 2024

Sleep boosts immune cell mobility toward lymph nodes

Researchers at LMU Munich have shown that sleep enhances the migratory potential of T cells toward lymph nodes.

8 Mar 2024

U-M research offers a new path forward in the development of anti-HIV drugs

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

8 Mar 2024

The effects of high maternal folate intake on the health outcomes of offspring

Researchers summarized what is known about the effects of excessive folic acid (FA) supplementation for mothers on children.

8 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers assessed the risk of depression following the diagnosis of rheumatoid arthritis (RA).

8 Mar 2024

Link between nutrient intake and multimorbidity risk reported in recent study, more research is needed

In a recent study published in BMC Public Health, researchers explored potential associations between nutrient intake and multimorbidities.

8 Mar 2024

Diabetes drug dulaglutide may reduce symptoms of depression

The current study highlighted the antidepressant effects of dulaglutide using the CMS depression model. Notably, the potential metabolisms that underlie the antidepressant effect of dulaglutide have been elucidated in this study.

8 Mar 2024

Tryptophan digestion by gut microbiome spurs arthritis inflammation

A University of Colorado Department of Medicine faculty member says she and her colleagues have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards arthritis.

7 Mar 2024

How your brain plans a route: A peek into navigational thinking

A study in Scientific Reports unveils the human brain's hierarchical processing for navigation, beginning with low-level 2D image analysis, followed by simultaneous mid-level 3D and high-level semantic processing, before concluding with navigational affordance representations, offering new insights into cognitive navigation strategies.

7 Mar 2024

Understanding long COVID: A call for better diagnosis and treatment

A recent review in Nature Reviews Microbiology summarizes the complex mechanisms, significant impacts, and the urgent need for enhanced diagnostics and treatments for long COVID, affecting over 65 million people globally with diverse, debilitating symptoms and systemic health issues.

7 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024

Adipose-derived stem cell exosomes play protective roles in mitigating myocardial injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the expression and therapeutic potential of circRNAs from adipose-derived stem cell (ADSC) exosomes (ADSC-Exos) for cardiomyocyte injury.

7 Mar 2024