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Research explores effect of DBS treatments in animals with brain injuries

The research, published in Behavioural Brain Research, was conducted by Pilar Segura and Ignacio Morgado (coordinators), Laura Aldavert and Marc Ramoneda, psychobiologists of the Institute of Neurosciences and the Department of Psychobiology and Health Sciences Methodology of the UAB and by Elisabet Kadar and Gemma Huguet, molecular biologists of the University of Girona, to explore the power of Deep Brain Stimulation treatments in the hypothalamus to recover the ability to learn and remember after a severe lesion of the amygdala.

28 Jan 2015

TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.

28 Jan 2015

Androgen receptor in prostate cancer cells can activate different gene set when bound to antiandrogens

The androgen receptor in prostate cancer cells can activate different sets of genes depending on whether it binds with an androgen hormone or an antiandrogen drug, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

28 Jan 2015

Researchers devise novel way to generate corneal stem cells for treating corneal blindness

Researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute have devised a novel way to generate transplantable corneal stem cells that may eventually benefit patients suffering from life-altering forms of blindness.

28 Jan 2015

Study links lysosomal dysfunction with neonatal intestinal disorders

Neonatal intestinal disorders that prevent infants from getting the nutrients they need may be caused by defects in the lysosomal system that occur before weaning, according to a new Northwestern Medicine study.

28 Jan 2015

Sanford-Burnham researchers use human pluripotent stem cells to grow new hair

In a new study from Sanford-Burnham Medical Research Institute, researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair loss.

28 Jan 2015

Georgia Tech researchers unveil new version of genome annotation system

Georgia Tech researchers, working with colleagues in the National Center for Biotechnology Information, have released a new version of a genome annotation system capable of analyzing more than 2,000 prokaryotic genomes per day, helping researchers accelerate prokaryotic genomics-based studies worldwide.

27 Jan 2015

Listeria poses pregnancy risk

A gut bacterium called Listeria (Listeria monocytogenes), which is often found in soft cheese, is known to present a risk to pregnant women. Listeria uses distinct tactics to breach the intestine and the placenta, using a protein called phosphoinositide-3 kinase (PI3-K), according to a study published in The Journal of Experimental Medicine.

27 Jan 2015

Case Western researchers awarded NSF grant to develop new method to reduce risk of Ebola virus

Health care workers must diagnose and isolate Ebola victims at an early stage to have a chance to save them and prevent the virus from spreading. But the most sensitive and quickest diagnostic test produces a small percentage of false negative results that undermine efforts to control the deadly agent.

27 Jan 2015

UNC researchers discover how two genes interact to trigger worst form of ovarian cancer

In the battle against ovarian cancer, UNC School of Medicine researchers have created the first mouse model of the worst form of the disease and found a potential route to better treatments and much-needed diagnostic screens.

27 Jan 2015

New study may lead to novel drug target for treating lung cancer

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat lung cancer.

27 Jan 2015

Penn scientists explore potential therapeutic target for cerebral cavernous malformations

Tens of millions of people around the world have abnormal, leak-prone sproutings of blood vessels in the brain called cerebral cavernous malformations (CCMs). These abnormal growths can lead to seizures, strokes, hemorrhages, and other serious conditions, yet their precise molecular cause has never been determined.

27 Jan 2015

CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

Resistance of leukemia cells to contemporary chemotherapy is one of the most formidable obstacles to treating acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Now researchers at Children's Hospital Los Angeles have designed and developed a new protein-based therapy they believe will prove highly effective against drug-resistant leukemia cells.

27 Jan 2015

Study shows differences in play behavior, brain activation patterns and stress levels in autistic children

Brain scans confirm significant differences in play behavior, brain activation patterns and stress levels in children with autism spectrum disorder (ASD) as compared with typically developing children.

27 Jan 2015

NovellusDx presents data from studies on Precision Cancer Analysis platform at PMWC 2015

NovellusDx, the leading Precision Cancer Analysis company delivering actionable intelligence about the mutational hierarchies that drive each patient’s cancer progression, announced today that the company will highlight data from studies on its Precision Cancer Analysis platform, at the Personalized Medicine World Conference 2015 in Silicon Valley.

27 Jan 2015

Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Cancer uses a little-understood element of cell signaling to hijack the communication process and spread, according to Rice University researchers.

27 Jan 2015

Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Scientists at the University of Saskatchewan College of Medicine, Department of Physiology, Saskatoon, Canada, led by Dr. Joseph Fomusi Ndisang have determined that upregulating heme-oxygenase with hemin improves pericardial adipocyte morphology and function.

27 Jan 2015

Imperial College professor honored with Helmholtz International Fellow Award

The British cell biologist Professor Amanda Gay Fisher of Imperial College London has been honored with the Helmholtz International Fellow Award for her excellent research. Fisher is one of seven outstanding researchers from abroad who received the award, each of which is endowed with 20,000 euros. According to the Helmholtz Association, Germany's largest scientific organization, the award also includes an invitation to visit one or several Helmholtz research centers.

27 Jan 2015

Researchers find methods to manipulate natural proteins that self-assemble into amyloid fibrils

Nature has many examples of self-assembly, and bioengineers are interested in copying or manipulating these systems to create useful new materials or devices. Amyloid proteins, for example, can self-assemble into the tangled plaques associated with Alzheimer's disease -- but similar proteins can also form very useful materials, such as spider silk, or biofilms around living cells.

27 Jan 2015

Progenitor cells responsible for generation and maintenance of Merkel cells

Researchers have identified a population of "progenitor" cells in the skin that are solely responsible for the generation and maintenance of touch-sensing Merkel cells. The study appears in The Journal of Cell Biology.

27 Jan 2015

Medical Science News

Research explores effect of DBS treatments in animals with brain injuries

TSRI scientists find drug candidates that can prevent degeneration of brain cells in Parkinson's

Androgen receptor in prostate cancer cells can activate different gene set when bound to antiandrogens

Researchers devise novel way to generate corneal stem cells for treating corneal blindness

Study links lysosomal dysfunction with neonatal intestinal disorders

Sanford-Burnham researchers use human pluripotent stem cells to grow new hair

Georgia Tech researchers unveil new version of genome annotation system

Listeria poses pregnancy risk

Case Western researchers awarded NSF grant to develop new method to reduce risk of Ebola virus

UNC researchers discover how two genes interact to trigger worst form of ovarian cancer

New study may lead to novel drug target for treating lung cancer

Penn scientists explore potential therapeutic target for cerebral cavernous malformations

CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

Study shows differences in play behavior, brain activation patterns and stress levels in autistic children

NovellusDx presents data from studies on Precision Cancer Analysis platform at PMWC 2015

Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Imperial College professor honored with Helmholtz International Fellow Award

Researchers find methods to manipulate natural proteins that self-assemble into amyloid fibrils

Progenitor cells responsible for generation and maintenance of Merkel cells

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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