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Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

The classic description of game theory was described by the prisoner's dilemma, which is a situation in which two players have two options where the outcome depends on the simultaneous choice made by the other.

29 Oct 2014

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year.

28 Oct 2014

Olympus cellSens imaging software 1.12 offers new functions

Assisting researchers in gaining a deeper understanding of dynamic biological processes, the new cellSens imaging software (version 1.12) ensures the most efficient use of valuable time-lapse experiments and the latest microscopy hardware. Building on the capabilities introduced by Olympus with its unique Graphical Experiment Manager (GEM) interface, cellSens 1.12 allows the user to truly get in touch with their sample.

From Evident Corporation - Life Sciences 28 Oct 2014

Lowering 'bad' cholesterol may help prevent aortic valve disease, study finds

An international research team led by the Research Institute of the McGill University Health Centre and Lund University has provided new evidence that aortic valve disease may be preventable.

28 Oct 2014

New research suggests that TEM5 protein may be a good target for cancer therapy

Do blood vessels that feed tumors differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more active in tumor-associated blood vessels than in normal blood vessels. New research now reveals the normal function of one of those genes and suggests it could be a good target for anticancer drug therapy.

28 Oct 2014

Understanding of genomic landscape of thyroid cancer

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients.

27 Oct 2014

Dietary cocoa flavanols can reverse age-related memory decline in healthy older adults

Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia University Medical Center scientists.

27 Oct 2014

Research findings support causal association between LDL-C, aortic valve disease

In an analysis that included approximately 35,000 participants, genetic predisposition to elevated low-density lipoprotein cholesterol (LDL-C) was associated with aortic valve calcium and narrowing of the aortic valve, findings that support a causal association between LDL-C and aortic valve disease, according to a study appearing in JAMA.

27 Oct 2014

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Scientists say they have identified in about 20 percent of colorectal and endometrial cancers a genetic mutation that had been overlooked in recent large, comprehensive gene searches. With this discovery, the altered gene, called RNF43, now ranks as one of the most common mutations in the two cancer types.

27 Oct 2014

Engineered cells reveal changes associated with learning, memory and reward

Scientists have created cells with fluorescent dyes that change color in response to specific neurochemicals. By implanting these cells into living mammalian brains, they have shown how neurochemical signaling changes as a food reward drives learning, they report in Nature Methods online October 26.

27 Oct 2014

Digoxin drug may be adaptable for ALS treatment, study suggests

Digoxin, a medication used in the treatment of heart failure, may be adaptable for the treatment of amyotrophic lateral sclerosis (ALS), a progressive, paralyzing disease, suggests new research at Washington University School of Medicine in St. Louis.

27 Oct 2014

Study sheds light on why we remember some things and not others

Why do we remember some things and not others? In a unique imaging study, two Northwestern University researchers have discovered how neurons in the brain might allow some experiences to be remembered while others are forgotten. It turns out, if you want to remember something about your environment, you better involve your dendrites.

27 Oct 2014

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Ludwig Oxford researchers have discovered a key mechanism that governs how cells of the epithelia, the soft lining of inner body cavities, shift between a rigid, highly structured and immobile state and a flexible and motile form.

27 Oct 2014

UT Southwestern assistant professor named Moore Investigator in Data-Driven Discovery

Dr. Kimberly Reynolds, Assistant Professor in the Cecil H. and Ida Green Comprehensive Center for Molecular, Computational, and Systems Biology and in the Department of Biophysics at UT Southwestern Medical Center, has been named one of 14 Moore Investigators in Data-Driven Discovery.

27 Oct 2014

Salk Institute scientists identify promising target for HIV/AIDS treatment

Like a slumbering dragon, HIV can lay dormant in a person's cells for years, evading medical treatments only to wake up and strike at a later time, quickly replicating itself and destroying the immune system.

27 Oct 2014

Scientists devise novel way to use stem cells in fight against brain cancer

Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by neuroscientist Khalid Shah, MS, PhD, who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses, now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

27 Oct 2014

Rewriting the family history of Ebola

The research shows that filoviruses — a family to which Ebola and its similarly lethal relative, Marburg, belong — are at least 16-23 million years old.

27 Oct 2014

Tiny nano-sized particles may play major role in detecting, tracking breast cancer

Exosomes, tiny, virus-sized particles released by cancer cells, can bioengineer micro-RNA (miRNA) molecules resulting in tumor growth. They do so with the help of proteins, such as one named Dicer. New research from The University of Texas MD Anderson Cancer Center suggests Dicer may also serve as a biomarker for breast cancer and possibly open up new avenues for diagnosis and treatment.

27 Oct 2014

New material advances tissue engineering, drug delivery

Researchers at the New York University Polytechnic School of Engineering have broken new ground in the development of proteins that form specialized fibers used in medicine and nanotechnology. For as long as scientists have been able to create new proteins that are capable of self-assembling into fibers, their work has taken place on the nanoscale. For the first time, this achievement has been realized on the microscale—a leap of magnitude in size that presents significant new opportunities for using engineered protein fibers.

27 Oct 2014

Cornell University chemists uncover new insight into the underlying causes of ALS

Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell University have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS).

27 Oct 2014

Medical Science News

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Olympus cellSens imaging software 1.12 offers new functions

Lowering 'bad' cholesterol may help prevent aortic valve disease, study finds

New research suggests that TEM5 protein may be a good target for cancer therapy

Understanding of genomic landscape of thyroid cancer

Dietary cocoa flavanols can reverse age-related memory decline in healthy older adults

Research findings support causal association between LDL-C, aortic valve disease

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Engineered cells reveal changes associated with learning, memory and reward

Digoxin drug may be adaptable for ALS treatment, study suggests

Study sheds light on why we remember some things and not others

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

UT Southwestern assistant professor named Moore Investigator in Data-Driven Discovery

Salk Institute scientists identify promising target for HIV/AIDS treatment

Scientists devise novel way to use stem cells in fight against brain cancer

Rewriting the family history of Ebola

Tiny nano-sized particles may play major role in detecting, tracking breast cancer

New material advances tissue engineering, drug delivery

Cornell University chemists uncover new insight into the underlying causes of ALS

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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