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Innovative bone marrow-on-a-chip microdevice holds promise for developing improved radiation countermeasures

Engineered bone marrow grown in a novel microfluidic chip device responds to damaging radiation exposure followed by treatment with compounds that aid in blood cell recovery in a way that mimics living bone marrow.

5 May 2016

High-fructose diet during pregnancy may affect fetal growth

Consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life, according to research in mice and people by a team at Washington University School of Medicine in St. Louis.

5 May 2016

Researchers develop pocket instrument capable of measuring electromagnetic radiation

A team of researchers from Center for Biomedical Technology at Universidad Politécnica de Madrid has developed a pocket instrument capable of perceiving radio signals from 50 MHz to 6 MHz and storing this information in a non-volatile memory. After collecting and storing the information, the system assesses the daily exposure of a person to electromagnetic radiation.

5 May 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Loyola researchers have identified a tumor gene that may help to predict survival outcomes in patients with cancer of the mouth and tongue.

5 May 2016

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

Winner of the Best International Abstract Award, Hadie Adams, presented his research, Characterizing the Temporal Evolution of ICP and Cerebrovascular Reactivity after Severe Traumatic Brain Injury, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

BioTek to present new technologies for cell-based applications at analytica 2016

BioTek will present two opportunities for researchers to learn about new instruments and approaches to simplify their workflow at analytica 2016, the 25th International Trade Fair for Laboratory Technology, Analysis, Biotechnology and analytica conference.

5 May 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That's the recipe for success reported by researchers at The Johns Hopkins University in a paper published April 18 online in ACS Biomaterials Science & Engineering.

5 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Researchers highlight how BSI infecting pathogens become more resilient

A recently published special issue of Virulence, "Bloodstream Infections", focuses on the resilience of bloodstream infections (BSI) and is endorsed by the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases.

5 May 2016

Michigan researchers use 'kidney on a chip' device to measure effect of drug doses on kidney cells

University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.

5 May 2016

Study analyzes PI, RI of patients who underwent AVM embolization and surgical resection

Winner of the Louise Eisenhardt Traveling Scholarship, Sophia F. Shakur, MD, IFAANS, presented her research, Changes in Pulsatility and Resistance Indices of Cerebral Arteriovenous Malformation Feeder Arteries after Embolization and Surgery, during the 2016 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.

4 May 2016

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.

4 May 2016

Muscle & Nerve study links intramuscular fat with BMI and physical activity levels

Ultrasound-estimated percent intramuscular fat of muscles in the lower extremity was inversely associated with physical activity level and positively associated with body mass index in a recent study.

4 May 2016

Researchers investigate incidence of new position-related nerve deficit in spine surgery

Winner of the Sanford J. Larson, MD, PhD, Award, Gurpreet Surinder Gandhoke, MD, presented his research, Incidence of Position Related Neuropraxia in 4,489 Consecutive Patients Undergoing Spine Surgery. Role of SSEP Monitoring? during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

Researchers detect five new genes that increase endometrial cancer risk in women

An international collaboration of researchers has identified five new gene regions that increase a woman's risk of developing endometrial cancer, one of the most common cancers to affect women, taking the number of known gene regions associated with the disease to nine.

4 May 2016

Scientists find that disruption to SCN rhythms can negatively impact overall health

Researchers have shown for the first time how neurons in the SCN are connected to each other, shedding light on this vital area of the brain. Understanding this structure — and how it responds to disruption — is important for tackling illnesses like diabetes and posttraumatic stress disorder. The scientists have also found that disruption to these rhythms such as shifts in work schedules or blue light exposure at night can negatively impact overall health.

4 May 2016

Scientists identify novel way of synthesising promising new antibiotic

A novel way of synthesising a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent.

4 May 2016

Medical Science News

Innovative bone marrow-on-a-chip microdevice holds promise for developing improved radiation countermeasures

High-fructose diet during pregnancy may affect fetal growth

Researchers develop pocket instrument capable of measuring electromagnetic radiation

Certain sugars in the body play key role in colitis, colon cancer development

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Researchers monitor ICP and PRx to characterize temporal evolution in severe TBI patients

BioTek to present new technologies for cell-based applications at analytica 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

Research provides new insight into cellular composition of IDH1-mutant gliomas

Human milk hormones may play vital role in shaping healthy infant microbiome

Researchers highlight how BSI infecting pathogens become more resilient

Michigan researchers use 'kidney on a chip' device to measure effect of drug doses on kidney cells

Study analyzes PI, RI of patients who underwent AVM embolization and surgical resection

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Muscle & Nerve study links intramuscular fat with BMI and physical activity levels

Researchers investigate incidence of new position-related nerve deficit in spine surgery

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

Researchers detect five new genes that increase endometrial cancer risk in women

Scientists find that disruption to SCN rhythms can negatively impact overall health

Scientists identify novel way of synthesising promising new antibiotic

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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