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U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer.

2 Apr 2016

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Scientists at Nanyang Technological University, Singapore have discovered that antibiotics can continue to be effective if bacteria's cell-to-cell communication and ability to latch on to each other are disrupted.

2 Apr 2016

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Researchers in the group of Prof. Dr. Peter Vandenabeele show that killed tumour cells can serve as a potent vaccine that stimulates the immune system to prevent the outgrowth of cancer cells.

2 Apr 2016

Lund researchers discover new biomarker that can predict type 2 diabetes risk

Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test. The results are published today in Nature Communications.

2 Apr 2016

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas (DLBCL). By reducing NFκB signaling, miR-181a controls tumor cell proliferation and survival and could be the target of novel therapies. The study was published in the journal Blood.

2 Apr 2016

Common viruses could produce mild to lethal cardiac injury

A review article has been published in the journal Current Pharmaceutical Design which provides an overview of therecent literature discussing the different clinical forms of heart disease resulting from virus infections including the prognosis, and current therapies.

2 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

Researchers uncover vital clues of how the brain erases long term memories

Vital clues about how the brain erases long term memories have been uncovered by researchers. The study in rats reveals how forgetting can be the result of an active deletion process rather than a failure to remember.

2 Apr 2016

Altered metabolism of two essential amino acids helps drive development of glioblastoma

The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Apr 2016

Excess activation of LOX may play causative role in progression of cardiac failure

Heart failure is a progressive condition, where structural and functional alterations of the ventricle limit the ability of the heart to either fill or eject blood. There are approximately 550,000 new cases of heart failure each year with a prevalence of nearly 5 million; most patients die within five years of diagnosis.

2 Apr 2016

New study raises possibility of therapeutic intervention for brain blood vessel disease

Cerebral cavernous malformations (CCM) are the most common cause of stroke in young people. These malformations also known as Cavernomas are present in 0.1-0.5% of the population, with about 60% causing symptoms. Currently there is no drug treatment available for CCM.

1 Apr 2016

German scientists use DNA molecules to make nanoscale component

In order for a machine to perform work, it needs parts that move relative to each other. This also holds true for nanoscale machines. German scientists have now used DNA molecules to make a nanoscale component that makes it possible for two individual parts to move relative to each other. As reported in the journal Angewandte Chemie, this component could be used as a molecular guide bearing and may form the basis for more complex systems.

1 Apr 2016

Study may help identify unborn children at higher risk for birth defects

Researchers at the University of Toronto have discovered a novel function performed by the breast cancer 1 protein (BRCA1), which regulates DNA repair. Well known for the role it plays in breast and ovarian cancer, this study revealed that the BRCA1 protein actually plays a much broader biological role, particularly in protecting the developing embryo from the damaging effects of reactive oxygen species (ROS).

1 Apr 2016

Purdue University-led researchers determine structure of Zika virus

A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines.

1 Apr 2016

New UCLA study reveals how the brain combines sound and vision

A new UCLA psychology study provides insights into how the brain combines sound and vision. The research suggests that there is not one sole mechanism in the brain that governs how much our senses work together to process information.

1 Apr 2016

Study links voluntary exercise during pregnancy to more physically active children

Baylor College of Medicine researchers have discovered that female mice that voluntarily exercise during pregnancy have offspring that are more physically active as adults. The research appears in The FASEB Journal.

1 Apr 2016

Aging reduces axonal regeneration after spinal cord injury

Older Americans are increasingly active, and this lifestyle shift has contributed to the rise in average age of a person experiencing a spinal cord injury. The changing demographic calls for a better understanding of how aging impacts recovery and repair after a spinal cord injury.

1 Apr 2016

Tumor suppressor p53 gene twice as likely to be defective in autistic children

A large study by researchers with the UC Davis MIND Institute has found that a gene whose role is to suppress cellular damage from environmental stressors is nearly twice as likely to be defective in children with autism spectrum disorder (ASD), and that the deficit is also present in their fathers.

1 Apr 2016

Experimental urine test identifies 92% of men with elevated PSA levels

An experimental urine test that detects genetic changes associated with prostate cancer identified 92 percent of men with elevated PSA (prostate-specific antigen) levels who had high-grade cancers, according to a study published today in JAMA Oncology online.

1 Apr 2016

Study points to possible new genetic risk factor for celiac disease

Researchers have identified a common variant in a non-coding RNA that may contribute to the intestinal inflammation that occurs in people with celiac disease. The findings point to a possible new risk factor for developing celiac disease in people with celiac disease risk genes.

1 Apr 2016

Medical Science News

U of S-led researchers develop novel class of compounds for effective cancer treatment

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Lund researchers discover new biomarker that can predict type 2 diabetes risk

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

Common viruses could produce mild to lethal cardiac injury

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Researchers uncover vital clues of how the brain erases long term memories

Altered metabolism of two essential amino acids helps drive development of glioblastoma

Excess activation of LOX may play causative role in progression of cardiac failure

New study raises possibility of therapeutic intervention for brain blood vessel disease

German scientists use DNA molecules to make nanoscale component

Study may help identify unborn children at higher risk for birth defects

Purdue University-led researchers determine structure of Zika virus

New UCLA study reveals how the brain combines sound and vision

Study links voluntary exercise during pregnancy to more physically active children

Aging reduces axonal regeneration after spinal cord injury

Tumor suppressor p53 gene twice as likely to be defective in autistic children

Experimental urine test identifies 92% of men with elevated PSA levels

Study points to possible new genetic risk factor for celiac disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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