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Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Researchers have discovered gene-targets (biomarkers) that may enable alternative treatments or the potential design of new drugs that target metastasis-promoting tumor genes.

22 Jan 2016

New study identifies DKK3 as a driver of kidney fibrosis

Chronic kidney disease can develop in response to a variety of insults and is characterized by progressive renal fibrosis and atrophy of kidney tubule. Therapeutic options are limited and the disease is often not detected until later stages.

22 Jan 2016

Blocking class II MHC molecules on graft endothelium limits acute rejection

A limitation of organ transplant is acute rejection of the graft by the host immune system. Graft rejection is mediated by the development of CD8+ cytotoxic T cells that target donor MHC class I molecules, and in animal models, these cells have been shown to develop in secondary lymphoid organs.

22 Jan 2016

New machine-learning technique could be used to uncover previously unknown features of organisms

A powerful new machine-learning technique can be applied to large datasets in the biological sciences to uncover previously unknown features of organisms and their genes, according to a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Jan 2016

MD Anderson and AbbVie join forces to design new immunotherapy cancer patients

The immunotherapy platform at The University of Texas MD Anderson Cancer Center and the global biopharmaceutical company AbbVie will join forces to find new ways to unleash the immune system's potential to fight cancer.

21 Jan 2016

Findings may explain why type 2 diabetic patients experience smelling problems

In a study in type 2 diabetic rats, researchers at the Karolinska Institutet have identified alterations in specific nerve cells that are important for odor identification. The findings might explain why type 2 diabetic patients often experience smelling problems and potentially open up a new research field to develop preventive therapies against neurodegenerative diseases in type 2 diabetic patients.

21 Jan 2016

Research sheds light on mechanism by which hemangioblasts become blood cells

A research group led by Lecturer Makoto Kobayashi of the University of Tsukuba Faculty of Medicine, has managed to shed light on the puzzling mechanism by which hemangioblasts become blood cells. Although hemangioblasts are the common precursor cells for blood cells and vascular endothelia that are present during the fetal period, the discovery of hemangioblasts in adult organisms has begun to garner attention from the medical world.

21 Jan 2016

Weekend junk food binges bad for your gut health

Yo-yoing between eating well during the week and bingeing on junk food over the weekend is likely to be just as bad for your gut health as a consistent diet of junk, new UNSW research suggests.

21 Jan 2016

Study explores role of genetic and environmental factors in development of social anxiety

Genes play a crucial role over time although environmental factors matter most in the short term, according to a major study into social anxiety and avoidant personality disorders from the Norwegian Institute of Public Health.

21 Jan 2016

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Scientists at Sanford Burnham Prebys Medical Discovery Institute have solved the atomic structure of a unique ubiquitin ligase complex. Ubiquitin is best known for its role in protein degradation, but more recently seen as important for cell signaling, DNA repair, anti-inflammatory, and immune responses.

21 Jan 2016

Northwestern researchers use fruit fly genetics to understand how things may go wrong in cancer

Cancer cells are normal cells that go awry by making bad developmental decisions during their lives. In a study involving the fruit fly equivalent of an oncogene implicated in many human leukemias, Northwestern University researchers have gained insight into how developing cells normally switch to a restricted, or specialized, state and how that process might go wrong in cancer.

21 Jan 2016

High-traffic 'hub neurons' may play role in understanding brain health

Just as most of the world's air travel passes through a few major hubs, the majority of information in the brain flows through similarly well-traveled routes, Indiana University scientists have found.

21 Jan 2016

Berlin researchers identify defects in myotubular myopathy

Tiny deviations in the body's cells can sometimes have severe consequences. Researchers from Berlin have discovered why cells from patients suffering from the rare muscular disease myotubular myopathy cannot function properly.

21 Jan 2016

Gene therapy holds considerable potential for safe, effective treatment of people with factor VII deficiency

Hematology researchers have used a single injection of gene therapy to correct a rare bleeding disorder, factor VII deficiency, in dogs. This success in large animals holds considerable potential for a safe, effective and long-lasting new treatment in humans with the same bleeding disorder.

21 Jan 2016

Study provides better understanding of familial risk for depression

Building on a 30-year, three-generation study of depressed individuals, their children and offspring, a study published in the journal Psychiatry Research: Neuroimaging provides a better understanding of the familial risk for depression and the role neuroplasticity might have in increasing the risk of developing depression.

21 Jan 2016

Study provides evidence for use of inherited genetic markers to improve melanoma prognostication

Melanoma is the most dangerous and lethal form of skin cancer. But just how long will a patient survive following the removal of a melanoma tumor? A more definitive answer to that question could come from new studies at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center. Researchers there have discovered an inherited genetic marker that might provide clinicians with a personalized tool to gauge an individual's survival and determine which patients require closer monitoring in the years following surgery.

21 Jan 2016

Medical Science News

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

New study identifies DKK3 as a driver of kidney fibrosis

Blocking class II MHC molecules on graft endothelium limits acute rejection

New machine-learning technique could be used to uncover previously unknown features of organisms

MD Anderson and AbbVie join forces to design new immunotherapy cancer patients

Findings may explain why type 2 diabetic patients experience smelling problems

Research sheds light on mechanism by which hemangioblasts become blood cells

Weekend junk food binges bad for your gut health

Study explores role of genetic and environmental factors in development of social anxiety

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Northwestern researchers use fruit fly genetics to understand how things may go wrong in cancer

High-traffic 'hub neurons' may play role in understanding brain health

Berlin researchers identify defects in myotubular myopathy

Gene therapy holds considerable potential for safe, effective treatment of people with factor VII deficiency

Study provides better understanding of familial risk for depression

Study provides evidence for use of inherited genetic markers to improve melanoma prognostication

Discovery may help researchers identify new ways to attack malaria parasite

UC Berkeley researchers make major improvement in CRISPR-Cas9 gene editing technology

Anxiety can make people to walk in a leftward trajectory

Study outlines new model to help predict age-related response to hepatitis B vaccine

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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