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MGH investigators develop system to accurately track the process of falling asleep

Massachusetts General Hospital investigators have developed a system to accurately track the dynamic process of falling asleep, something has not been possible with existing techniques. In their report in the October issue of the open-access journal PLOS Computational Biology, the research team describes how combining key physiologic measurements with a behavioral task that does not interfere with sleep onset gives a better picture of the gradual process of falling asleep.

21 Nov 2014

SRY protein alters specific gender-related tissue in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges.

21 Nov 2014

Researchers discover a new way to combat influenza virus infection

The influenza virus, like all viruses, is a hijacker. It quietly slips its way inside cells, steals the machinery inside to make more copies of itself, and then -- having multiplied -- bursts out of the cell to find others to infect.

21 Nov 2014

University of Texas student receives Robert D. Watkins Graduate Research Fellowship

Veronica Garcia, a student at The University of Texas Graduate School of Biomedical Sciences at Houston, has been awarded a Robert D. Watkins Graduate Research Fellowship from the American Society for Microbiology.

21 Nov 2014

Protein complex plays key role in detecting tumor cells, promotes anti-tumor response

A recently discovered protein complex known as STING plays a crucial role in detecting the presence of tumor cells and promoting an aggressive anti-tumor response by the body's innate immune system, according to two separate studies published in the Nov. 20 issue of the journal Immunity.

21 Nov 2014

Researchers reveal mechanism that determines direction of egg flow in fallopian tubes

Researchers in Japan have revealed the mechanism that determines the direction of the transportation of eggs in the fallopian tube.

21 Nov 2014

Personalized dietary advice based on person's genetic makeup improves eating habits

Personalized dietary advice based on a person's genetic makeup improves eating habits compared to current "one-size-fits-all" dietary recommendations, says a University of Toronto researcher.

21 Nov 2014

Researchers identify genetic signatures in melanoma tumors that predict response to immunotherapy

A team led by Ludwig and Memorial Sloan Kettering (MSK) researchers has published a landmark study on the genetic basis of response to a powerful cancer therapy known as immune checkpoint blockade.

21 Nov 2014

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions.

20 Nov 2014

Stress can be helpful when it comes to emotionally relevant information

Retrieving memory content under stress does not work very well. However, stress can be helpful when it comes to saving new information -- especially those that are emotionally relevant in stressful situations.

20 Nov 2014

TSRI study examines body’s own response against chronic protein misfolding

“Protein misfolding” diseases such as cystic fibrosis and Alzheimer’s may be seriously exacerbated by the body’s own response against that misfolding, according to a new study led by scientists at The Scripps Research Institute.

20 Nov 2014

People who handle complex jobs may have longer-lasting memory and thinking abilities

People whose jobs require more complex work with other people, such as social workers and lawyers, or with data, like architects or graphic designers, may end up having longer-lasting memory and thinking abilities compared to people who do less complex work, according to research published in the November 19, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Nov 2014

Study shows how stem cells can help regenerate damaged muscle after heart attack

Delivering stem cell factor directly into damaged heart muscle after a heart attack may help repair and regenerate injured tissue, according to a study led by researchers from Icahn School of Medicine at Mount Sinai presented November 18 at the American Heart Association Scientific Sessions 2014 in Chicago, IL.

19 Nov 2014

Changes in one gene can influence person's cholesterol levels from midlife through late life

It's known that cholesterol levels typically rise as people age and that high cholesterol levels are associated with increased risk of cardiovascular disease. What's less known is that cholesterol levels begin to decline the more a person ages. Recently, researchers from the University of Texas Medical Branch at Galveston and the University of Kentucky found that differences in one gene can influence a person's cholesterol levels from midlife to late life.

19 Nov 2014

Targeting bacterial motility to combat chronic respiratory disease

Mycoplasma gallisepticum causes chronic respiratory disease in birds. The illness particularly affects domestic chicken and turkey flocks. The bacteria are especially life-threatening for the animals when they occur in combination with other infections. In order to control the spread of the disease, poultry farms in the EU must be proven free from Mycoplasma gallisepticum or face being closed.

19 Nov 2014

Gene therapy transforms life for men with severe form of hemophilia B

Gene therapy developed at St. Jude Children's Research Hospital, University College London and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting protein Factor IX that has allowed some to adopt a more active lifestyle, researchers reported.

19 Nov 2014

Scientists unravel molecular mechanisms that drive ferroptosis signaling

Ferroptosis is a recently recognized form of regulated necrosis. Up until now, this form of cell death has only been thought to be a possible therapeutic approach to treat tumour cells. Yet, ferroptosis also occurs in non-transformed tissues as demonstrated by this study, thus implicating this cell death pathway in the development of a wide range of pathological conditions. More specifically, the deletion of the ferroptosis-regulating enzyme Gpx4 in a pre-clinical model results in high ferroptosis rates in kidney tubular epithelial cells causing acute renal failure.

19 Nov 2014

New method could make Ebola surveillance quicker, cheaper for West African nations

A new method for examining the Ebola virus genome could make surveillance quicker and cheaper for West African nations, and help detect new forms of the virus. The detailed procedure is being shared with the research community along with the study paper, which is freely available in the open access journal Genome Biology.

19 Nov 2014

Researchers find drug combination that reduces risk of skin graft rejection

A research team bringing together José Cohen and Philippe Grimbert (Inserm Unit 955/Université Paris Est Créteil [UPEC] and the Centre for Clinical Investigation - Biotherapies 504 [CIC-BT 504]), and their collaborators at Institut Curie and AP-HP (George Pompidou European Hospital) has succeeded in finding a combination of drugs that reduces the risk of rejection following a skin graft.

19 Nov 2014

Blocking key brain receptor cell could neutralize biological consequences of Alzheimer's

Blocking a key receptor in brain cells that is used by oxygen free radicals could play a major role in neutralizing the biological consequences of Alzheimer's disease, according to researchers at Temple University.

19 Nov 2014

Medical Science News

MGH investigators develop system to accurately track the process of falling asleep

SRY protein alters specific gender-related tissue in males before birth

Researchers discover a new way to combat influenza virus infection

University of Texas student receives Robert D. Watkins Graduate Research Fellowship

Protein complex plays key role in detecting tumor cells, promotes anti-tumor response

Researchers reveal mechanism that determines direction of egg flow in fallopian tubes

Personalized dietary advice based on person's genetic makeup improves eating habits

Researchers identify genetic signatures in melanoma tumors that predict response to immunotherapy

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

Stress can be helpful when it comes to emotionally relevant information

TSRI study examines body’s own response against chronic protein misfolding

People who handle complex jobs may have longer-lasting memory and thinking abilities

Study shows how stem cells can help regenerate damaged muscle after heart attack

Changes in one gene can influence person's cholesterol levels from midlife through late life

Targeting bacterial motility to combat chronic respiratory disease

Gene therapy transforms life for men with severe form of hemophilia B

Scientists unravel molecular mechanisms that drive ferroptosis signaling

New method could make Ebola surveillance quicker, cheaper for West African nations

Researchers find drug combination that reduces risk of skin graft rejection

Blocking key brain receptor cell could neutralize biological consequences of Alzheimer's

Making Complex Cell Culture Easy and Efficient with AI

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

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