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NIH-funded study explores how thalamic reticular nucleus influences consciousness

Ever wonder why it's hard to focus after a bad night's sleep? Using mice and flashes of light, scientists show that just a few nerve cells in the brain may control the switch between internal thoughts and external distractions.

16 Aug 2014

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Researchers from Boston University School of Medicine report that a tumor suppressor pathway, called the Hippo pathway, is responsible for sensing abnormal chromosome numbers in cells and triggering cell cycle arrest, thus preventing progression into cancer.

16 Aug 2014

Researchers study LDLR protein using new, groundbreaking techniques

Researchers from the Copenhagen Center for Glycomics at the University of Copenhagen have studied an important receptor protein called LDLR using new, groundbreaking techniques. The protein plays an important role in the absorption of the bad cholesterol, LDL.

16 Aug 2014

Dopamine replacement therapy increases impulse control disorders in newly diagnosed PD patients

New Penn Medicine research shows that neuropsychiatric symptoms such as depression, anxiety and fatigue are more common in newly diagnosed Parkinson's disease (PD) patients compared to the general population.

16 Aug 2014

Illness-linked genetic variation affects connections among neurons in the developing brain

A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports.

16 Aug 2014

Findings may help identify teens who are at risk for dangerous behaviors in the future

According to the CDC, unintentional injuries are the leading cause of death for adolescents. Compared to the two leading causes of death for all Americans, heart disease and cancer, a pattern of questionable decision-making in dire situations comes to light in teen mortality.

16 Aug 2014

Anti-EphA3 antibody has anti-tumour effects against solid cancers

An international team of scientists has shown that an antibody against the protein EphA3, found in the micro-environment of solid cancers, has anti-tumour effects.

16 Aug 2014

Vitamin D deficiency linked to higher surgical risk

Patients with low blood levels of vitamin D are at increased risk of death and serious complications after noncardiac surgery, suggests a study in Anesthesia & Analgesia.

16 Aug 2014

Researchers review potential of adipose-derived stem cells to improve nerve regeneration

Stem cell researchers at the Blond McIndoe Laboratory, University of Manchester, UK, led by Dr Adam Reid, present a review of the current literature on the suitability of adipose-derived stem cells in peripheral nerve repair.

16 Aug 2014

Researchers now have a clear picture of bacterial immune system

Bacteria's ability to destroy viruses has long puzzled scientists, but researchers at the Johns Hopkins Bloomberg School of Public Health say they now have a clear picture of the bacterial immune system and say its unique shape is likely why bacteria can so quickly recognize and destroy their assailants.

15 Aug 2014

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

15 Aug 2014

Research offers promise for personalized RNA combination therapies to treat lung cancer

Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential for new therapeutic agents to inhibit cancer cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body.

15 Aug 2014

Researchers develop new lung-on-chip model for laboratory studies of respiratory challenges

Researchers at RTI International, in collaboration with the University of North Carolina at Chapel Hill, have developed a new lung-on-chip microdevice for laboratory studies of respiratory challenges and therapeutics. The microdevice includes multiple vertically stacked cellular layers that mimic the structure of the airway tissue.

15 Aug 2014

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

A team of researchers at Mayo Clinic and The Scripps Research Institute in Florida have developed a new therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD).

15 Aug 2014

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

15 Aug 2014

HDAC inhibitors may also be effective against kidney stones

Anyone who has suffered from kidney stones is keenly aware of the lack of drugs to treat the condition, which often causes excruciating pain.

15 Aug 2014

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

A modified version of the Clostridium novyi (C. novyi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer Center researchers.

14 Aug 2014

Yizhijiannao granule may exert therapeutic effect by inhibiting neural cell apoptosis

Previous studies have shown that Yizhijiannao granule can enhance cognitive performance in Alzheimer's disease patients and Alzheimer's disease-model mice.

14 Aug 2014

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective.

14 Aug 2014

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers at Karolinska Institutet in Sweden have found a method to repair the gene mutation causing agammaglobulinemia, an autoimmune deficiency disease that almost exclusively affects boys and in which the body lacks the ability to produce immunoglobulins (gamma globulin).

14 Aug 2014

Medical Science News

NIH-funded study explores how thalamic reticular nucleus influences consciousness

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Researchers study LDLR protein using new, groundbreaking techniques

Dopamine replacement therapy increases impulse control disorders in newly diagnosed PD patients

Illness-linked genetic variation affects connections among neurons in the developing brain

Findings may help identify teens who are at risk for dangerous behaviors in the future

Anti-EphA3 antibody has anti-tumour effects against solid cancers

Vitamin D deficiency linked to higher surgical risk

Researchers review potential of adipose-derived stem cells to improve nerve regeneration

Researchers now have a clear picture of bacterial immune system

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

Research offers promise for personalized RNA combination therapies to treat lung cancer

Researchers develop new lung-on-chip model for laboratory studies of respiratory challenges

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

NTU research could lead to better treatment options for children suffering from leukaemia

HDAC inhibitors may also be effective against kidney stones

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

Yizhijiannao granule may exert therapeutic effect by inhibiting neural cell apoptosis

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Researchers find method to repair gene mutation causing autoimmune deficiency disease

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

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