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New rabbit model provides insights into CF-related pancreatic endocrine pathology

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication.

17 Jan 2025

SOX9 overexpression protects against lipid accumulation in MASH via AMPK activation

The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical role in organ development.

17 Jan 2025

DDR2 enhances BMP-dependent bone regeneration and reduces heterotopic ossification

Bone loss resulting from trauma, fractures, or disease presents a major global health challenge, often leading to long-term disability.

17 Jan 2025

Exploring the role of EpCAM in early-stage hepatocellular carcinoma progression

Announcing a new publication for Acta Materia Medica journal. Epithelial cell adhesion molecule (EpCAM) is a biomarker for epithelial cell-derived tumors.

17 Jan 2025

Key biomarkers linked to obesity-induced heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Many studies have reported that obesity causes heart failure (HF) pathogenesis.

17 Jan 2025

The diverse immunological functions of megakaryocytes

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

17 Jan 2025

UAB research unveils structural brain changes in pregnant women

A study led by the UAB has analyzed the brains of women during pregnancy for the first time using neuroimaging techniques.

17 Jan 2025

RNA damage plays key role in sunburn reaction

Sunburn has traditionally been attributed to UV-induced DNA damage. However, a new study by the University of Copenhagen and Nanyang Technological University, Singapore, reveals that RNA, another vital cellular molecule, plays a major role in triggering acute sunburn reactions.

17 Jan 2025

Researchers launch startup to revolutionize targeted drug delivery using milk exosomes

Two Nebraska researchers have launched a startup company aimed at bringing to market an innovative method for delivering therapeutics, gene editing tools, plasmids and more to targeted locations in the human body.

17 Jan 2025

New study links cervicovaginal microbiome to increased risk of Chlamydia infections

The cervicovaginal microbiome's role in Chlamydia infections underscores the need for molecular classification to enhance prevention and treatment strategies.

17 Jan 2025

Granzyme K+ CD8+ T-cells identified as key drivers of recurrent airway inflammation

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

17 Jan 2025

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Intestinal bacterium found to reduce sugar intake in diabetic mice and humans

Excessive sugar consumption is linked to several non-communicable diseases, including obesity, cardiovascular disease, metabolic syndrome, and type 2 diabetes.

17 Jan 2025

Over 500 European patients diagnosed through groundbreaking genetic research

More than 500 European patients with unknown conditions have received a diagnosis through new genetic research.

17 Jan 2025

Brain neurons that respond to sugar and fat offer new insights into obesity control

The study uncovers hippocampal neurons that differentially respond to sugars and fats, suggesting new avenues for combating obesity through targeted therapies.

17 Jan 2025

Tofacitinib reduces SARS-CoV-2 infection risk in patients with PTPN2 deficiency

Researchers report the ability of tofacitinib to reduce infection risk with SARS-CoV-2 in individuals who are deficient in PTPN2.

17 Jan 2025

Oil-based solution enables room temperature storage of protein therapeutics

A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold. The discovery, led by researchers at Penn State, could eliminate the need for refrigeration for hundreds of life-saving medicines like insulin, monoclonal antibodies and viral vaccines.

17 Jan 2025

Bidirectional movement drives DNA loop formation

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make loops into DNA could move in one direction only. The discovery, which is published in Cell, is key to understanding how these motors shape our genome and regulate our genes.

17 Jan 2025

Immune cells orchestrate glucagon production during fasting

When we think about the immune system, we usually associate it with fighting infections. However, a study published in Science by the Champalimaud Foundation reveals a surprising new role.

17 Jan 2025

AI deciphers intracellular signals from extracellular recordings in heart cells

A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need to physically penetrate the cells.

16 Jan 2025

Medical Science News

New rabbit model provides insights into CF-related pancreatic endocrine pathology

SOX9 overexpression protects against lipid accumulation in MASH via AMPK activation

DDR2 enhances BMP-dependent bone regeneration and reduces heterotopic ossification

Exploring the role of EpCAM in early-stage hepatocellular carcinoma progression

Key biomarkers linked to obesity-induced heart failure

The diverse immunological functions of megakaryocytes

UAB research unveils structural brain changes in pregnant women

RNA damage plays key role in sunburn reaction

Researchers launch startup to revolutionize targeted drug delivery using milk exosomes

New study links cervicovaginal microbiome to increased risk of Chlamydia infections

Granzyme K+ CD8+ T-cells identified as key drivers of recurrent airway inflammation

Inflammasome proteins found to prevent cancer by regulating stem cells

Intestinal bacterium found to reduce sugar intake in diabetic mice and humans

Over 500 European patients diagnosed through groundbreaking genetic research

Brain neurons that respond to sugar and fat offer new insights into obesity control

Tofacitinib reduces SARS-CoV-2 infection risk in patients with PTPN2 deficiency

Oil-based solution enables room temperature storage of protein therapeutics

Bidirectional movement drives DNA loop formation

Immune cells orchestrate glucagon production during fasting

AI deciphers intracellular signals from extracellular recordings in heart cells

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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