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Metabolon agrees to provide biochemical profiling services to Human Longevity

Metabolon, Inc., the world's leading commercial-stage metabolomics company, announces the signing of an agreement with newly-launched Human Longevity Inc., whereby Metabolon will provide biochemical profiling services to assist HLI in its mission to tackle diseases of aging by building the world's largest and most complete human genotype, microbiome and phenotype database.

5 Mar 2014

Researchers develop adjuvant which enhances effect of virus transduction

Lentiviruses, which belong to the family of retroviruses, are used as vectors to exchange genetic material in cells and can be used to replace a defective gene as defined by gene therapy.

5 Mar 2014

UTHealth study to assess deep brain stimulation for treatment-resistant depression

A pilot study at The University of Texas Health Science Center at Houston (UTHealth) will assess the use of deep brain stimulation (DBS) in the medial forebrain bundle of the brain for treatment-resistant depression.

5 Mar 2014

Set of genes appear to predict which tumors can evade detection by immune system

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

5 Mar 2014

Cell-cycle arrest biomarkers validated for acute kidney injury

Saeed A. Jortani, Ph.D., associate clinical professor in the University of Louisville's Department of Pathology and Laboratory Medicine, headed up one of three labs in the United States involved in determining two new markers for acute kidney injury (AKI). The research group's paper, "Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication," was posted online Feb. 25 by the American Journal of Respiratory and Critical Care Medicine.

5 Mar 2014

Plant pigment could prevent damage to nerves linked with childhood form of SMA

The research team have found that a plant pigment called quercetin - present in some fruits, vegetables, herbs and grains - could help to prevent damage to the nerves associated with the childhood form of motor neurone disease, spinal muscular atrophy (SMA).

5 Mar 2014

Researchers find ways to selectively pinpoint and target cancer cells

In current research related to improving cancer treatments, one promising area of research is the effort to find ways to selectively pinpoint and target cancer cells while minimizing effects on healthy cells.

5 Mar 2014

$Researchers develop silk-based surgical plates and screws to repair bone fractures$

Researchers develop silk-based surgical plates and screws to repair bone fractures

When a person suffers a broken bone, treatment calls for the surgeon to insert screws and plates to help bond the broken sections and enable the fracture to heal. These "fixation devices" are usually made of metal alloys.

5 Mar 2014

Human Longevity, UC San Diego sign new collaborative research agreement

The new collaborative research agreement between Human Longevity Inc. and the University of California, San Diego, announced today, represents a significant and necessary step in efforts to research and translate the potential of the human genome into novel and real treatments and therapies able to change and improve the human condition.

5 Mar 2014

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

The bacterium Staphylococcus aureus (S. aureus) is a common source of infections that occur after surgeries involving prosthetic joints and artificial heart valves. The grape-shaped microorganism adheres to medical equipment, and if it gets inside the body, it can cause a serious and even life-threatening illness called a Staph infection. The recent discovery of drug-resistant strains of S. aureus makes matters even worse.

5 Mar 2014

Removing gut bacteria may play critical role in reducing cancer risk

Bacteria in the gut are essential for the development of intestinal tumors in mice, according to research led by investigators from the Icahn School of Medicine at Mount Sinai. Removing the bacteria may play a critical role in reducing cancer risk, the researchers write, in the March issue of the Journal of Experimental Medicine.

5 Mar 2014

Medical diagnoses, DNA sequencing can be made faster through gel electrophoresis

Medical diagnoses and DNA sequencing can be made cheaper, faster and more reliable using a new miniaturized technique for gel electrophoresis based on conducting polymer materials, according to researchers at Link-ping University in Sweden.

5 Mar 2014

Researchers unravel function of proteins involved in cell metabolism

UCPs or uncoupling proteins are present in mitochondria, the powerhouse of each cell in the body. The functions of most of the five known UCPs remain mysterious (UCP2-UCP5), whereby only the distinct function for UCP1 has thus far been discovered.

5 Mar 2014

Researchers identify genes that appear to predict tumors that can evade detection by immune system

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body’s immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

5 Mar 2014

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

A combination of iron-oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth-Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.

5 Mar 2014

New probes help to quantify normally folded and misfolded conformations of protein in cells

Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.

5 Mar 2014

Study: Thickness of brain's cortex linked with person's change in IQ

Rate of change in the thickness of the brain's cortex is an important factor associated with a person's change in IQ, according to a collaborative study by scientists in five countries including researchers at the Montreal Neurological Institute and Hospital - The Neuro, at McGill University and the McGill University Health Centre.

5 Mar 2014

Tel Aviv University researchers discover link between sharp vision and the brain's processing speed

Middle-aged adults who suddenly need reading glasses, patients with traumatic brain injuries, and people with visual disorders such as "lazy eye" may have one thing in common --"visual crowding," an inability to recognize individual items surrounded by multiple objects. Visual crowding makes it impossible to read, as single letters within words are rendered illegible. And basic cognitive functions such as facial recognition can also be significantly hampered. Scientists and clinicians currently attribute crowding to a disorder in peripheral vision.

5 Mar 2014

Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

In a new study that could help doctors extend the lives of patients awaiting liver transplants, a Rice University-led team of researchers examined the metabolic breakdown that takes place in liver cells during late-stage cirrhosis and found clues that suggest new treatments to delay liver failure.

5 Mar 2014

Nerve cells from horse stem cells may pave way for cell therapies, say researchers

Horses suffering from neurological conditions similar to those that affect humans could be helped by a breakthrough from stem cell scientists.

5 Mar 2014

Medical Science News

Metabolon agrees to provide biochemical profiling services to Human Longevity

Researchers develop adjuvant which enhances effect of virus transduction

UTHealth study to assess deep brain stimulation for treatment-resistant depression

Set of genes appear to predict which tumors can evade detection by immune system

Cell-cycle arrest biomarkers validated for acute kidney injury

Plant pigment could prevent damage to nerves linked with childhood form of SMA

Researchers find ways to selectively pinpoint and target cancer cells

Researchers develop silk-based surgical plates and screws to repair bone fractures

Human Longevity, UC San Diego sign new collaborative research agreement

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

Removing gut bacteria may play critical role in reducing cancer risk

Medical diagnoses, DNA sequencing can be made faster through gel electrophoresis

Researchers unravel function of proteins involved in cell metabolism

Researchers identify genes that appear to predict tumors that can evade detection by immune system

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

New probes help to quantify normally folded and misfolded conformations of protein in cells

Study: Thickness of brain's cortex linked with person's change in IQ

Tel Aviv University researchers discover link between sharp vision and the brain's processing speed

Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

Nerve cells from horse stem cells may pave way for cell therapies, say researchers

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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