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Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Promethera Biosciences, a company that develops innovative therapies for the treatment of liver diseases, today announces a collaboration with EMD Millipore to develop an improved ready-to-use microfluidic perfusion liver assay. This new product is designed to perform more robust studies in pre-clinical toxicity and drug metabolism.

11 Mar 2014

Sugars attached to proteins can be used to detect ovarian cancer, say researchers

The hunt is on to find biomarkers that detect cancer, but it's a challenging process. Early successes often are followed by heartbreaking failures. But now, researchers at UC Davis have verified that glycans (sugars attached to proteins) can be used to detect ovarian cancer. The study was published online in the journal Cancer Epidemiology, Biomarkers & Prevention.

11 Mar 2014

Glycoprofiling test could halve number of false-positives in diagnosis of ovarian cancer

The world's most widespread test for ovarian cancer reports false-positives in 94 of 100 diagnosed cases. Now, chemists at the University of Copenhagen working with clinical researchers at University College London have developed a method able to halve the number of false-positives.

11 Mar 2014

Genetic basis of hereditary disease causes severe brain atrophy in Jews of Moroccan ancestry

Ben-Gurion University of the Negev (BGU) researchers have unraveled the genetic basis of a hereditary disease that causes severe brain atrophy, mental retardation and epilepsy in Jews of Moroccan ancestry, according to a study published this week online in the Journal of Medical Genetics.

11 Mar 2014

Researchers identify microbe that 'eats' electricity

There have been plenty of fad diets that captured the public's imagination over the years, but Harvard scientists have identified what may be the strangest of them all - sunlight and electricity.

11 Mar 2014

Harvard Review of Psychiatry provides updates on ASD research

Recent years have seen exciting progress in key areas of research on autism spectrum disorders (ASD): from possible genetic causes, to effective treatments for common symptoms and clinical problems, to promoting success for young people with ASD entering college. Updates on these and other advances in ASD research are presented in the March special issue of Harvard Review of Psychiatry.

10 Mar 2014

Study gives insights into designing new drugs to fight infections

Efforts to combat bacteria’s growing resistance to antibiotics could be helped by a key discovery about the complex processes that enable bugs to thrive.

10 Mar 2014

Tubulin protein is a well-validated cancer drug target

Tubulin, the building-block protein of cellular microtubules, is a well-validated cancer drug target: Disrupting tubulin polymerization affects cytoskeletal function and thus cell division.

10 Mar 2014

WuXi Genome Center buys Illumina HiSeq X Ten sequencing system

Illumina, Inc. and WuXi PharmaTech (Cayman) Inc., a leading pharmaceutical, biotechnology, and medical device R&D outsourcing company with operations in China and the United States, today announced that the WuXi Genome Center has purchased an Illumina HiSeq X Ten sequencing system.

From Illumina, Inc. 10 Mar 2014

Healthy dietary choices in midlife may prevent dementia in later years

Healthy dietary choices in midlife may prevent dementia in later years, according a doctoral thesis published at the University of Eastern Finland. The results showed that those who ate the healthiest diet at the average age of 50 had an almost 90 per cent lower risk of dementia in a 14-year follow-up study than those whose diet was the least healthy.

10 Mar 2014

Decision-making accuracy can be improved by postponing onset of decision

Columbia University Medical Center (CUMC) researchers have found that decision-making accuracy can be improved by postponing the onset of a decision by a mere fraction of a second.

10 Mar 2014

Researchers determine affected areas of brain using speech processing tests with aid of fMRT

The brain processes read and heard language differently. This is the key and new finding of a study at the University Department of Radiology and Nuclear Medicine at the MedUni Vienna, unveiled on the eve of the European Radiology Congress in Vienna (6 to 10 March).

10 Mar 2014

Study: Stem cell transplant effective in halting degenerative disc disease of spine

Stem cell transplant was viable and effective in halting or reversing degenerative disc disease of the spine, a meta-analysis of animal studies showed, in a development expected to open up research in humans.

10 Mar 2014

Conditioned pain modulation decreases activity in human spinal cord, say researchers

Researchers have demonstrated that conditioned pain modulation (CPM), a measure of the brain's ability to regulate pain, decreases activity in the human spinal cord as visible via functional magnetic resonance imaging (fMRI).

10 Mar 2014

Researchers seek to understand causes of premature birth with support from March of Dimes

Five researchers seeking to understand the causes of premature birth with the goal of identifying women at risk of preterm labor and developing new treatments to prevent it have been awarded grant support from the March of Dimes.

10 Mar 2014

CIBMTR recognizes SCCA's Fred Hutchinson Bone Marrow Transplant Program

The Fred Hutchinson Bone Marrow Transplant Program at Seattle Cancer Care Alliance was recently recognized by the Center for International Blood and Marrow Transplant Research for outperforming its expected one-year survival rate for allogeneic transplant patients. The results published by the CIBMTR, analyzed the National Marrow Donor Program's (NMDP) registry of 168 U.S. transplant centers over a three-year period for its 2013 Transplant Center-Specific Survival Report.

10 Mar 2014

Biomarkers for bone resorption predict outcomes for men with prostate cancer

Biomarkers for bone formation and resorption predict outcomes for men with castration-resistant prostate cancer, a team of researchers from UC Davis and their collaborators have found.

10 Mar 2014

Researchers find that protein synthesis can be studied in adult stem cells

For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells - something scientists have long struggled to accomplish. The groundbreaking findings from the Children's Medical Center Research Institute at UT Southwestern (CRI) also demonstrate that the precise amount of protein produced by blood-forming stem cells is crucial to their function.

10 Mar 2014

New theory regarding cause and development of endometriosis

Changes to two previously unstudied genes are the centerpiece of a new theory regarding the cause and development of endometriosis, a chronic and painful disease affecting 1 in 10 women.

10 Mar 2014

Takeda works with UCL to drive research into tackling muscle disorders

Japanese pharmaceutical company Takeda will work with University College London (UCL) to drive research into tackling muscle disorders, in particular muscular dystrophy.

10 Mar 2014

Medical Science News

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Sugars attached to proteins can be used to detect ovarian cancer, say researchers

Glycoprofiling test could halve number of false-positives in diagnosis of ovarian cancer

Genetic basis of hereditary disease causes severe brain atrophy in Jews of Moroccan ancestry

Researchers identify microbe that 'eats' electricity

Harvard Review of Psychiatry provides updates on ASD research

Study gives insights into designing new drugs to fight infections

Tubulin protein is a well-validated cancer drug target

WuXi Genome Center buys Illumina HiSeq X Ten sequencing system

Healthy dietary choices in midlife may prevent dementia in later years

Decision-making accuracy can be improved by postponing onset of decision

Researchers determine affected areas of brain using speech processing tests with aid of fMRT

Study: Stem cell transplant effective in halting degenerative disc disease of spine

Conditioned pain modulation decreases activity in human spinal cord, say researchers

Researchers seek to understand causes of premature birth with support from March of Dimes

CIBMTR recognizes SCCA's Fred Hutchinson Bone Marrow Transplant Program

Biomarkers for bone resorption predict outcomes for men with prostate cancer

Researchers find that protein synthesis can be studied in adult stem cells

New theory regarding cause and development of endometriosis

Takeda works with UCL to drive research into tackling muscle disorders

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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