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Bioinformatics researchers investigate functional diversity of proteins

No two human beings are the same. Although we all possess the same genes, our genetic code varies in many places. And since genes provide the blueprint for all proteins, these variants usually result in numerous differences in protein function. But what impact does this diversity have? Bioinformatics researchers at Rutgers University and the Technische Universitaet Muenchen have investigated how protein function is affected by changes at the DNA level.

6 Sep 2013

Molecular marker predicts longer survival among patients prescribed two cancer drugs

Johns Hopkins scientists have identified a molecular marker called "Mig 6" that appears to accurately predict longer survival -- up to two years -- among patients prescribed two of the most widely used drugs in a class of anticancer agents called EGFR inhibitors.

6 Sep 2013

Researchers translate new technology to better study behaviors and cellular function to fruit flies

A team of researchers led by Charles D. Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has successfully translated a new technology to better study behaviors and cellular function to fruit flies.

6 Sep 2013

Vanderbilt's telemedicine initiative conducts follow-up hearing tests on newborns in rural areas

A telemedicine initiative in Vanderbilt's Department of Hearing and Speech Sciences is working to make follow-up hearing tests for newborns more accessible in rural areas of Tennessee, while teaching young pediatric audiology and pediatric speech language pathology students to treat patients remotely.

6 Sep 2013

Researchers develop method for purifying cardiac muscle cells using molecular beacons

Pure cardiac muscle cells, ready to transplant into a patient affected by heart disease. That's a goal for many cardiology researchers working with stem cells. Having a pure population of cardiac muscle cells is essential for avoiding tumor formation after transplantation, but has been technically challenging.

6 Sep 2013

New gene that causes cystic kidneys in children, young adults identified

Sylvia Hoff, a graduate student from the Spemann Graduate School of Biology and Medicine, has identified a new gene that causes cystic kidneys in children and young adults.

6 Sep 2013

International team of scientists discover new disease related to inability to process Vitamin B12

An international team of scientists, including University of Colorado School of Medicine and Children's Hospital Colorado researchers, has discovered a new disease related to an inability to process Vitamin B12.

6 Sep 2013

Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction

Increased brain cell apoptosis in intrauterine growth-restricted fetal rats is a key reason for unfavorable long-term prognosis of the nervous system. The harmful effects of intrauterine growth restriction on fetal brain development originate in the womb.

6 Sep 2013

Scientists reveal structure of protein essential for triggering necroptosis

Scientists in Melbourne, Australia, have revealed the structure of a protein that is essential for triggering a form of programmed cell death called necroptosis, making possible the development of new drugs to treat chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis.

6 Sep 2013

Apoptosis can reactivate latent herpesviruses in dying cell

Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in the Journal of Virology.

6 Sep 2013

Self-propagating aggregates key to Alzheimer's, other diseases

Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them.

6 Sep 2013

Planarian flatworm: An ideal model to study molecular basis of regeneration

Unlike humans, planarian flatworms have the remarkable ability to regrow any missing body part, making them an ideal model with which to study the molecular basis of regeneration.

5 Sep 2013

Processing of sound in brain is more advanced than previously thought

The processing of sound in the brain is more advanced than previously thought. When we hear a tone, our brain temporarily strengthens that tone but also any tones separated from it by one or more octaves. A research team from Utrecht and Nijmegen published an article on the subject in the journal PNAS on 2 September.

5 Sep 2013

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

A stressful pregnancy might be the last thing a future mother needs, but it is to her unborn baby that this stress spells real trouble. All because stress hormones (called glucocorticoids or GCs) can disturb normal foetal brain development, leading to behavioural and/or emotional problems later in life.

5 Sep 2013

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Heart attack patients with ST elevation who undergo a preventive procedure to unblock additional coronary arteries have significantly better outcomes than those whose treatment is confined to the culprit blockage only, according to the results of the Preventive Angioplasty in Myocardial Infarction (PRAMI) Trial

5 Sep 2013

Researchers explore seas and oceans to discover novel antibiotics and other medical compounds

The life that inhabits the world's oceans has almost infinite variety. It remains an untapped source of diversity. "The oceans can be deep or shallow, they can be more or less tidal, and they can include unique environments such as volcanic vents," says Brian McNeil ofStrathclyde University in Scotland, UK.

5 Sep 2013

Olympus to showcase next generation of inverted microscope systems at EMBO Meeting 2013

Demonstrating the very latest in live cell imaging technologies, Olympus will exhibit its range of IX3 inverted microscope frames with associated software and accessories at the upcoming European Molecular Biology Organisation Meeting 2013, taking place in Amsterdam on 21-24 September.

From Evident Corporation - Life Sciences 5 Sep 2013

Natural products: The source of nearly half of modern drugs

New technology for discovering antibiotics, anti-cancer drugs and other medicines inside soil microbes and other natural sources is reviving a treasure hunt that already has given humanity more than 50 percent of today's prescription drugs. This new era in "bioprospecting" is the topic of the cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.

5 Sep 2013

Leopoldina Annual Assembly to focus on factors that shape individual personalities

The German National Academy of Sciences Leopoldina will focus on the theme "Geist - Gehirn - Genom - Gesellschaft ("Mind, brain, genome and society") at its 2013 Annual Assembly, which will take place from 20 to 22 September and welcome over 400 guests from around the world to Halle (Saale).

5 Sep 2013

Obesity gene testing may help reduce self-blame

Obesity gene testing does not put people off weight loss and may help to reduce self-blame, according to a new study by researchers from the Health Behaviour Research Centre at UCL (University College London).

5 Sep 2013

Medical Science News

Bioinformatics researchers investigate functional diversity of proteins

Molecular marker predicts longer survival among patients prescribed two cancer drugs

Researchers translate new technology to better study behaviors and cellular function to fruit flies

Vanderbilt's telemedicine initiative conducts follow-up hearing tests on newborns in rural areas

Researchers develop method for purifying cardiac muscle cells using molecular beacons

New gene that causes cystic kidneys in children, young adults identified

International team of scientists discover new disease related to inability to process Vitamin B12

Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction

Scientists reveal structure of protein essential for triggering necroptosis

Apoptosis can reactivate latent herpesviruses in dying cell

Self-propagating aggregates key to Alzheimer's, other diseases

Planarian flatworm: An ideal model to study molecular basis of regeneration

Processing of sound in brain is more advanced than previously thought

Dopamine improves deficiencies in social behavior, could have implications for neuropsychiatric disorders

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Researchers explore seas and oceans to discover novel antibiotics and other medical compounds

Olympus to showcase next generation of inverted microscope systems at EMBO Meeting 2013

Natural products: The source of nearly half of modern drugs

Leopoldina Annual Assembly to focus on factors that shape individual personalities

Obesity gene testing may help reduce self-blame

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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