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Researchers identify genetic link specific to risk of childhood leukemia

For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, University of Washington, and other institutions. The discovery was reported online today in the journal Nature Genetics.

10 Sep 2013

Ferritin protects kidneys against damage by controlling iron

A protein, ferritin, protects kidneys against a damaging after-effect of injury, heart failure or hardened arteries by controlling levels of iron, according to a study published today by researchers at the University of Alabama at Birmingham in the Journal of Clinical Investigation.

10 Sep 2013

Breath tests could be non-invasive method of diagnosing lung cancer

Collecting samples of exhaled breath from people at a high risk of lung cancer could be a cheap and non-invasive method of diagnosing the disease, according to new research.

10 Sep 2013

Researchers investigate importance of STAT1 phosphorylation in NK cells

Since its discovery in the early 1990s, the protein STAT1 (Signal Transducer and Activator of Transcription 1) has been found to be central in passing signals across immune cells, ensuring that our bodies react quickly and appropriately to threats from viruses or other pathogens.

7 Sep 2013

Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment

Synthetic antidepressants present a narrow spectrum and side effects following long-term application. Recently, medical practitioners have shown interest in the use of Chinese medicines for the treatment of diseases and in the adjustment of the human response to stress.

7 Sep 2013

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) symposium, Harnessing the Paradox: Personalization and the Science of Scale, to be held in October 2013, will address topics of direct relevance to translational science.

7 Sep 2013

Study reveals hydrolyzed collagen may be suitable for nerve cell culture media

In the central nervous system, nerve cells adhere to the extracellular matrix. Type I collagen is the major class of insoluble fibrous proteins in the extracellular matrix. A previous study has shown that neural stem and progenitor cells, cultured on collagen matrices, are able to expand actively and generate neurons.

7 Sep 2013

Research team receives nearly $17M to focus on nanopore technology in DNA sequencing

The use of nanopore technology aimed at more accurate and efficient DNA sequencing is the main focus of grants awarded by the National Institutes of Health. The grants - nearly $17 million to eight research teams - are the latest awarded through the National Human Genome Research Institute (NHGRI)'s Advanced DNA Sequencing Technology program, which was launched in 2004. NHGRI is part of NIH.

7 Sep 2013

BMP linked to increased risk of benign tumors, not cancers

Patients undergoing spinal fusion surgery with bone morphogenetic protein (BMP) appear to be at increased risk of benign tumors—but not cancers, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

7 Sep 2013

Researchers take detailed images of morphing structure of Parkinson’s protein

Researchers have taken detailed images and measurements of the morphing structure of a brain protein thought to play a role in Parkinson's disease, information that could aid the development of medications to treat the condition.

7 Sep 2013

Basic fibroblast growth factor can protect endplate in motor neurons of injured spinal cord

In current studies, the degeneration and protection measures in the distal end of the injured spinal cord and target organ muscle effector have scarcely been investigated. The distal end of the spinal cord and neuromuscular junction may develop secondary degenera-tion and damage following spinal cord injury because of the loss of neural connections.

7 Sep 2013

Northumbria University psychologist to introduce diners to the science behind food and drink

Diners will discover how the food on their plate can impact their brain function at a special dining experience during the British Science Festival in Newcastle.

6 Sep 2013

Trovagene, University of Southern California enter into clinical collaboration agreement

Trovagene, Inc., a developer of molecular diagnostics for cancer monitoring, today announced that the Company has entered into a clinical collaboration agreement with the University of Southern California to study genomic characterizations of metastatic colorectal cancers using Trovagene's proprietary cell-free DNA assays.

6 Sep 2013

TSRI scientists identify involvement of angiomotin protein in cancer

A team led by scientists from The Scripps Research Institute have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth.

6 Sep 2013

Locus coeruleus plays major role in learning, memory and other cognitive functions

Death of neurons in the dorsal raphe nucleus and locus coeruleus is a pathological characteristic of the disease. Previous studies concerning the pathological characteristic of Alzheimer's disease mainly focus on learning and memory-related hippocampus, and less attention has been paid to the locus coeruleus.

6 Sep 2013

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

It is widely believed that bone marrow mesenchymal stem cells are highly adherent fibroblastic cells, defined as colony-forming unit-fibroblasts. Nevertheless, a few reports have shown that the non-adherent bone marrow cells can give rise to colony-forming unit-fibroblasts in vitro, and possess a certain differentiation potential.

6 Sep 2013

Study could help facilitate understanding of behavioural, emotional interactions between people

A study from Karolinska Institutet in Sweden has shown that neurons in our brain 'mirror' the space near others, just as if this was the space near ourselves. The study, published in the scientific journal Current Biology, sheds new light on a question that has long preoccupied psychologists and neuroscientists regarding the way in which the brain represents other people and the events that happens to those people.

6 Sep 2013

Myeloid derived suppressor cells provide niche where cancer stem cells survive

The immune system is normally known for protecting the body from illness. But a subset of immune cells appear to be doing more harm than good.

6 Sep 2013

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Researchers at the University of Alberta announced today that they have determined the chemical composition of human urine. The study, which took more than seven years and involved a team of nearly 20 researchers, has revealed that more than 3,000 chemicals or "metabolites" can be detected in urine.

6 Sep 2013

Researchers explore distinctions between natural sleep and anesthetic unconsciousness

Falling asleep in your bed at night and being "put to sleep" under general anesthesia - as well as waking up in the morning or coming out of anesthesia - aren't quite the same thing, yet they share some important similarities. Max Kelz, MD, PhD, assistant professor of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania, along with colleagues from Penn, UCSD, Howard Hughes Medical Institute, and Thomas Jefferson University, explored the distinctions between anesthetic unconsciousness and sleep by manipulating the genetic pathways known to be involved in natural sleep and studying the resulting effects on anesthetic states.

6 Sep 2013

Medical Science News

Researchers identify genetic link specific to risk of childhood leukemia

Ferritin protects kidneys against damage by controlling iron

Breath tests could be non-invasive method of diagnosing lung cancer

Researchers investigate importance of STAT1 phosphorylation in NK cells

Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

Study reveals hydrolyzed collagen may be suitable for nerve cell culture media

Research team receives nearly $17M to focus on nanopore technology in DNA sequencing

BMP linked to increased risk of benign tumors, not cancers

Researchers take detailed images of morphing structure of Parkinson’s protein

Basic fibroblast growth factor can protect endplate in motor neurons of injured spinal cord

Northumbria University psychologist to introduce diners to the science behind food and drink

Trovagene, University of Southern California enter into clinical collaboration agreement

TSRI scientists identify involvement of angiomotin protein in cancer

Locus coeruleus plays major role in learning, memory and other cognitive functions

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

Study could help facilitate understanding of behavioural, emotional interactions between people

Myeloid derived suppressor cells provide niche where cancer stem cells survive

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Researchers explore distinctions between natural sleep and anesthetic unconsciousness

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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