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UTHealth researchers find cause for rare type of bleeding disorder

Fifteen years ago, a hematologist came to Dianna Milewicz, M.D., Ph.D., with a puzzle: Multiple generations of an East Texas family suffered from a moderately severe bleeding disorder, but it wasn't hemophilia.

28 Aug 2013

UW researchers perform first noninvasive human-to-human brain interface

University of Washington researchers have performed what they believe is the first noninvasive human-to-human brain interface, with one researcher able to send a brain signal via the Internet to control the hand motions of a fellow researcher.

28 Aug 2013

Research shows specific form of memory associations is encoded in cerebral cortex

'Where' and 'how' memories are encoded in a nervous system is one of the most challenging questions in biological research. The formation and recall of associative memories is essential for an independent life. The hippocampus has long been considered a centre in the brain for the long-term storage of spatial associations.

28 Aug 2013

High intensity interval training offers maximum benefits to women

Interval training is a well-known way to get the maximum benefits of exercise in the shortest amount of time. New research shows that when it comes to running, women may get more out of high intensity interval training (HIIT) than their male counterparts.

28 Aug 2013

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

Stomach cancer, one of the leading causes of cancer death worldwide, actually falls into three broad subtypes that respond differently to currently available therapies, according to researchers at Duke-NUS Graduate Medical School Singapore.

28 Aug 2013

New polymer additives enhance ability of oral drugs to reach bloodstream

All too often, when a person takes a pill full of a potent and effective drug, the drug passes straight through the body, not reaching the organ where it is needed — a waste of money and inconvenient if it is a cold medicine, but potentially dire if it is a treatment for a serious illness.

28 Aug 2013

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

Joslin scientists, in collaboration with researchers from the Harvard School of Public Health and Italian research institutes, have identified a previously unknown genetic variant associated with an increased risk of coronary heart disease (CHD) in type 2 diabetic patients.

28 Aug 2013

'Helper cells' improve survival rate of transplanted stem cells, finds study

Like volunteers handing out cups of energy drinks to marathon runners, specially engineered "helper cells" transplanted along with stem cells can dole out growth factors to increase the stem cells' endurance, at least briefly, Johns Hopkins researchers report.

28 Aug 2013

Human exposure to aluminium implicates number of chronic diseases

Aluminium - the most abundant metal and third most abundant element of the Earth's crust - has no known biological function and is a recognised environmental toxin. Human exposure to aluminium is implicated in a number of chronic diseases, including bone disease, auto-immune conditions, cancer and neurodegenerative diseases.

28 Aug 2013

Study: Apoptosis triggers alternate replication pathway in HHV

Washington, DC-Researchers from Children's National Medical Center have found that an alternate, "escape" replication process triggered by apoptosis-the process of cell death or "cell suicide"-appears to be common in human herpesviruses (HHV).

28 Aug 2013

Daily doses of calcium and vitamin supplements may not prevent loss of BMD in women

Women undergoing treatment for breast cancer are widely prescribed calcium and vitamin D supplements to prevent and manage osteoporosis, an unwanted side effect of breast cancer therapies.

28 Aug 2013

Researchers identify genetic locus associated with increased risk of CHD in type 2 diabetes patients

Researchers have identified a previously unknown genetic locus (the place a gene occupies on a chromosome) significantly associated with increased coronary heart disease risk among patients with type 2 diabetes, but the association was not found in individuals without diabetes, according to a study in the August 28 issue of JAMA.

28 Aug 2013

New compound offers way to treat migraine and other disorders of central nervous system

For many migraine sufferers, bright lights are a surefire way to exacerbate their headaches. And for some night-shift workers, just a stroll through a brightly lit parking lot during the morning commute home can be enough to throw off their body's daily rhythms and make daytime sleep nearly impossible. But a new molecule that selectively blocks specialized light-sensitive receptors in the eyes could help both these groups of people, without affecting normal vision.

28 Aug 2013

Researchers find specific protein in nearly all high-grade meningiomas

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas -- the most common form of brain tumor -- suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

CST introduces HER3 antibody for studying HER2-mediated breast, lung and ovarian tumors

Cell Signaling Technology, Inc. of Danvers, MA, announced today that it has introduced a highly specific HER3 rabbit monoclonal antibody (mAb), an important addition for researchers studying HER2-mediated breast, lung and ovarian tumors.

From Cell Signaling Technology 28 Aug 2013

Life Technologies announces end-to-end sequencing solution for whole human exome CNV analysis

Life Technologies Corporation today announced the first end-to-end sequencing solution for exon-level copy number variation analysis, which combines the Ion Reporter CNV data analysis workflow, the Ion AmpliSeq Exome Kit and the Ion Proton® System.

27 Aug 2013

Sigma Life Science releases genome editing tool for screening and exploratory studies

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, released Sigma CRISPRs, an inexpensive mammalian genome editing tool suitable for screening and exploratory studies.

27 Aug 2013

BiondVax: Priming with universal flu vaccine makes conventional bird flu vaccine effective against pandemic strains

BiondVax announced today that priming with universal flu vaccine before boosting with a conventional bird flu H5N1 vaccine (containing a single strain from Clade 1) resulted in mice exhibiting a significantly higher level of immunity to the strain contained in the conventional bird flu vaccine and in addition, broadened immunity to other H5N1 flu strains (from Clade 2).

27 Aug 2013

2ml deep well plate launched by Porvair Sciences

Porvair Sciences has developed the first 96-well round deep well plate that genuinely delivers 2.00 ml liquid capacity / well in an automation compatible SLAS / ANSI footprint. The revolutionary "common wall" design provides a full 2ml round well, round bottom well within a 45mm height limit, thus ensuring full compatibility with most plate handling equipment.

From Porvair Sciences Limited 27 Aug 2013

Vanderbilt adds genetic screening for drug tacrolimus to PREDICT program

Vanderbilt has added genetic screening for the drug tacrolimus to its personalize medicine pharmacogenomics program PREDICT. The new drug screening protocol was added following data that shows a single genetic variation largely impacts different dose requirements for patients.

27 Aug 2013

Medical Science News

UTHealth researchers find cause for rare type of bleeding disorder

UW researchers perform first noninvasive human-to-human brain interface

Research shows specific form of memory associations is encoded in cerebral cortex

High intensity interval training offers maximum benefits to women

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

New polymer additives enhance ability of oral drugs to reach bloodstream

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

'Helper cells' improve survival rate of transplanted stem cells, finds study

Human exposure to aluminium implicates number of chronic diseases

Study: Apoptosis triggers alternate replication pathway in HHV

Daily doses of calcium and vitamin supplements may not prevent loss of BMD in women

Researchers identify genetic locus associated with increased risk of CHD in type 2 diabetes patients

New compound offers way to treat migraine and other disorders of central nervous system

Researchers find specific protein in nearly all high-grade meningiomas

CST introduces HER3 antibody for studying HER2-mediated breast, lung and ovarian tumors

Life Technologies announces end-to-end sequencing solution for whole human exome CNV analysis

Sigma Life Science releases genome editing tool for screening and exploratory studies

BiondVax: Priming with universal flu vaccine makes conventional bird flu vaccine effective against pandemic strains

2ml deep well plate launched by Porvair Sciences

Vanderbilt adds genetic screening for drug tacrolimus to PREDICT program

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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