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Compatibility gene may influence finding life partner as well as our health, individuality

A University of Manchester professor and his wife have had their own DNA analysed for compatibility as part of the research for a new book out on 1 October in the US and next week in the UK.

From The University of Manchester 26 Aug 2013

The way gut "tastes" sweet food may be defective in sufferers of type 2 diabetes

Researchers at the University of Adelaide have discovered that the way the gut "tastes" sweet food may be defective in sufferers of type 2 diabetes, leading to problems with glucose uptake.

26 Aug 2013

Scientists discover mechanisms of GATA3 gene that govern blood stem cell self-renewal process

Stem cell scientists at the Princess Margaret Cancer Centre have discovered the gene GATA3 has a role in how blood stem cells renew themselves, a finding that advances the quest to expand these cells in the lab for clinical use in bone marrow transplantation, a procedure that saves thousands of lives every year.

26 Aug 2013

CeBiTec researchers successfully sequence genome of Chinese hamster

Genome researchers from Bielefeld University's Center for Biotechnology (CeBiTec) headed by Professor Dr. Alfred P-hler have succeeded in sequencing the genome of the Chinese hamster. The Chinese hamster supplies the cell cultures used by the pharmaceutical industry to produce biopharmaceutical products such as antibodies used in medicine.

26 Aug 2013

Scientists identify specific type of receptor that may aid in treatment of AD, Parkinson’s disease

Scientists at Washington University School of Medicine in St. Louis have found a way that corrupted, disease-causing proteins spread in the brain, potentially contributing to Alzheimer's disease, Parkinson's disease and other brain-damaging disorders.

26 Aug 2013

UCSF researchers identify possible mechanism for drug-seeking behavior in humans

Mice given cocaine showed rapid growth in new brain structures associated with learning and memory, according to a research team from the Ernest Gallo Clinic and Research Center at UC San Francisco. The findings suggest a way in which drug use may lead to drug-seeking behavior that fosters continued drug use, according to the scientists.

26 Aug 2013

Researchers discover additional cystic fibrosis-causing mutations

Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis, it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. In so doing, they have increased the number of known CF-causing mutations from 22 to 127, accounting for 95 percent of the variations found in patients with CF.

26 Aug 2013

Study reveals elegant circuit in visual system helps dictate how eyes connect to brain

A study in mice reveals an elegant circuit within the developing visual system that helps dictate how the eyes connect to the brain. The research, funded by the National Institutes of Health, has implications for treating amblyopia, a vision disorder that occurs when the brain ignores one eye in favor of the other.

26 Aug 2013

Study identifies 22 locations in the human genome that cause schizophrenia

A new genome-wide association study estimates the number of different places in the human genome that are involved in schizophrenia.

26 Aug 2013

Scientists discover crucial role of nitric oxide in cellular signaling and health

Scientists at the University of Illinois at Chicago College of Pharmacy have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health.

26 Aug 2013

Study compares spectrum of cancer-related gene mutations in two common types of cervical cancer

A new study has revealed marked differences in the genomic terrain of the two most common types of cervical cancer, suggesting that patients might benefit from therapies geared to each type's molecular idiosyncrasies.

26 Aug 2013

UC Berkeley study finds cocaine can dominate high-level brain circuits

Cocaine can speedily rewire high-level brain circuits that support learning, memory and decision-making, according to new research from the University of California, Berkeley, and UCSF. The findings shed new light on the frontal brain's role in drug-seeking behavior and may be key to tackling addiction.

26 Aug 2013

Model including dozens of mutations helps clarify genetic factors involved in Crohn's disease

A statistical model accounting for dozens of different genes in combination-and the interactions between them-is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease (CD), reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

26 Aug 2013

Glutathione peroxidase activity protects against symptoms of Huntington's disease

Leicester geneticists have discovered a potential defence against Huntington's disease - a fatal neurodegenerative disorder which currently has no cure.

26 Aug 2013

DeNovoGear software uses statistical probabilities to help identify genetic mutations

Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others are associated with diseases and disease susceptibility.

26 Aug 2013

BES procedure may prevent cell apoptosis in stem cell-based transplantation therapy

Researchers at the Beihang University School of Biological Science and Medical Engineering, led by Dr. Yubo Fan, have discovered that Biphasic Electrical stimulation (BES), a non-chemical procedure, may be used as a strategy for preventing cell apoptosis in stem cell-based transplantation therapy.

26 Aug 2013

Researchers identify compound that eases symptoms of Parkinson's disease

Researchers at Johns Hopkins and elsewhere have brought new clarity to the picture of what goes awry in the brain during Parkinson's disease and identified a compound that eases the disease's symptoms in mice.

26 Aug 2013

University of York reveals early ancestors had taste for spicy food

Our early ancestors had a taste for spicy food, new research led by the University of York has revealed.

26 Aug 2013

Scientists discover that chromosomal rearrangements can be advantageous

In a pioneer study published in the latest issue of the scientific journal Nature Communications, a research team at the Instituto Gulbenkian de Ci-ncia (IGC; Portugal), led by Miguel Godinho Ferreira in collaboration with Isabel Gordo, show for the first time that chromosomes rearrangements (such as inversions or translocations) can provide advantages to the cells that harbor them depending on the environment they are exposed.

23 Aug 2013

Article sheds new light on differences between normal aging and Alzheimer's disease

The ability of different regions of the brain to communicate gradually breaks down with aging and in Alzheimer's disease, but there are key differences between these two processes. Some of these differences are reported in a study that compared neural networks, signaling efficiency, and disruptions in connectivity in the brains of healthy elderly subjects and patients with Alzheimer's disease.

23 Aug 2013

Medical Science News

Compatibility gene may influence finding life partner as well as our health, individuality

The way gut "tastes" sweet food may be defective in sufferers of type 2 diabetes

Scientists discover mechanisms of GATA3 gene that govern blood stem cell self-renewal process

CeBiTec researchers successfully sequence genome of Chinese hamster

Scientists identify specific type of receptor that may aid in treatment of AD, Parkinson’s disease

UCSF researchers identify possible mechanism for drug-seeking behavior in humans

Researchers discover additional cystic fibrosis-causing mutations

Study reveals elegant circuit in visual system helps dictate how eyes connect to brain

Study identifies 22 locations in the human genome that cause schizophrenia

Scientists discover crucial role of nitric oxide in cellular signaling and health

Study compares spectrum of cancer-related gene mutations in two common types of cervical cancer

UC Berkeley study finds cocaine can dominate high-level brain circuits

Model including dozens of mutations helps clarify genetic factors involved in Crohn's disease

Glutathione peroxidase activity protects against symptoms of Huntington's disease

DeNovoGear software uses statistical probabilities to help identify genetic mutations

BES procedure may prevent cell apoptosis in stem cell-based transplantation therapy

Researchers identify compound that eases symptoms of Parkinson's disease

University of York reveals early ancestors had taste for spicy food

Scientists discover that chromosomal rearrangements can be advantageous

Article sheds new light on differences between normal aging and Alzheimer's disease

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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