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Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

A new publication in the top-ranked journal Neuron sheds new light onto the unknown processes on how the brain integrates the inputs from the different senses in the complex circuits formed by molecularly distinct types of nerve cells. The work was led by new Ume- University associate professor Paolo Medini.

21 Aug 2013

UC Davis graduate discovers how eIF4E protein acts upon cancer-promoting mRNA molecules

Researchers have long known that high levels of a specific protein in human cells are linked to tumor growth - but no one has fully understood how.

21 Aug 2013

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

The concept behind gene therapy is simple: deliver a healthy gene to compensate for one that is mutated. New research published today in the Journal of Neuroscience suggests this approach may eventually be a feasible option to treat Rett Syndrome, the most disabling of the autism spectrum disorders.

21 Aug 2013

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for Perinatal Research and pediatric surgeon for the Department of Pediatric Surgery at Nationwide Children's Hospital, and her team have found that this may just be the case with HB-EGF, or heparin-binding EGF-like growth factor.

21 Aug 2013

Sodium act as "on/off" switch for major neurotransmitter receptor in brain

Researchers at McGill University have found that sodium - the main chemical component in table salt - is a unique "on/off" switch for a major neurotransmitter receptor in the brain. This receptor, known as the kainate receptor, is fundamental for normal brain function and is implicated in numerous diseases, such as epilepsy and neuropathic pain.

21 Aug 2013

Combination of anti-nausea drug and turmeric spice target cancer cells

In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules that effectively kill multiple myeloma cells.

20 Aug 2013

3-D structure of proteins show flame retardants can mimic estrogen hormones

By determining the three-dimensional structure of proteins at the atomic level, researchers at the National Institutes of Health have discovered how some commonly used flame retardants, called brominated flame retardants (BFRs), can mimic estrogen hormones and possibly disrupt the body's endocrine system. BFRs are chemicals added or applied to materials to slow or prevent the start or growth of fire.

20 Aug 2013

RNA biomarkers in blood may identify people at risk for committing suicide

Indiana University School of Medicine researchers have found a series of RNA biomarkers in blood that may help identify who is at risk for committing suicide.

20 Aug 2013

Research: 2 forms of iron to treat cystic fibrosis lung infection

The bacterium Pseudomonas aeruginosa needs iron to establish and maintain a biofilm in the lungs of cystic fibrosis patients, and therapies have been proposed to deprive the bacteria of this necessary element.

20 Aug 2013

mUsiKcare aims to enhance student training, community engagement through piano classes

Through tickling the ivories a group of adults over the age of 50 at the University of Kentucky are learning ways to enhance their personal relationships and relieve anxiety all while advancing their skills on the piano.

20 Aug 2013

Pathophysiological abnormalities in preclinical phase of AD may be detected using CSF or neuroimaging biomarkers

Both A- and tau pathology appear to be associated with default mode network integrity before clinical onset of Alzheimer disease (AD), according to a study by Liang Wang, M.D., and colleagues at Washington University in St. Louis, Missouri.

20 Aug 2013

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Patients with an aggressive lymphoma that often relapses and kills within two years experienced a remission of their cancer and stayed disease-free as long as 28 months after taking a commercially-available drug that made chemotherapy more effective.

20 Aug 2013

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

mmunetics, Inc., a leading clinical test provider, has received U.S. Food and Drug Administration (FDA) clearance for its BacTx® rapid test for bacteria in apheresis platelets. The BacTx system is a colorimetric assay that can detect aerobic, anaerobic, gram-negative and gram-positive bacteria in a single test.

20 Aug 2013

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

New research at Rutgers University may help shed light on how and why nervous system changes occur and what causes some people to suffer from life-threatening anxiety disorders while others are better able to cope.

20 Aug 2013

Advance team of molecules produced by primary tumor is responsible for lung cancer metastasis

Cancer metastasis requires tumor cells to acquire properties that allow them to escape from the primary tumor site, travel to a distant place in the body, and form secondary tumors. But first, an advance team of molecules produced by the primary tumor sets off a series of events that create a network of nurturing blood vessels for arriving primary tumor cells to set up shop.

20 Aug 2013

Study shows superantigens produced by staph bacteria cause infective endocarditis and sepsis

University of Iowa researchers have discovered what causes the lethal effects of staphylococcal infective endocarditis - a serious bacterial infection of heart valves that kills approximately 20,000 Americans each year.

20 Aug 2013

Physical-activity adviser motivates old Latino adults to participate in exercise program

When it comes to getting motivated to exercise and do things that are good for our health, sometimes all it takes is a little help from our friends.

20 Aug 2013

Researchers study connections between brain network damage and Alzheimer's disease

In patients with early Alzheimer's disease, disruptions in brain networks emerge about the same time as chemical markers of the disease appear in the spinal fluid, researchers at Washington University School of Medicine in St. Louis have shown.

20 Aug 2013

Study shows complement activation plays an important role in inherited macular degeneration

In a study published on line this week in the journal Human Molecular Genetics, Drs. Donita Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School, along with their colleagues, reported the unexpected finding that in mice genetically engineered to have an inherited form of macular degeneration, turning off the animals' complement system, a part of the immune system, prevented the disease.

20 Aug 2013

Researchers create mouse models to advance the study of unusual deadly diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of these unusual but deadly diseases.

20 Aug 2013

Medical Science News

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

UC Davis graduate discovers how eIF4E protein acts upon cancer-promoting mRNA molecules

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

Sodium act as "on/off" switch for major neurotransmitter receptor in brain

Combination of anti-nausea drug and turmeric spice target cancer cells

3-D structure of proteins show flame retardants can mimic estrogen hormones

RNA biomarkers in blood may identify people at risk for committing suicide

Research: 2 forms of iron to treat cystic fibrosis lung infection

mUsiKcare aims to enhance student training, community engagement through piano classes

Pathophysiological abnormalities in preclinical phase of AD may be detected using CSF or neuroimaging biomarkers

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

Advance team of molecules produced by primary tumor is responsible for lung cancer metastasis

Study shows superantigens produced by staph bacteria cause infective endocarditis and sepsis

Physical-activity adviser motivates old Latino adults to participate in exercise program

Researchers study connections between brain network damage and Alzheimer's disease

Study shows complement activation plays an important role in inherited macular degeneration

Researchers create mouse models to advance the study of unusual deadly diseases

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

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