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Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers create an efficient technique to target and repair defective genes

Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to target and repair defective genes.

13 Aug 2013

Nuevolution forms scientific collaboration to investigate biological mechanism of GPCR drug target

Nuevolution A/S today announced that it has entered into a scientific collaboration with Duke University, the Howard Hughes Medical Institute, and Lexicon Pharmaceuticals, Inc. for the investigation of the biological mechanism of action of a specified GPCR drug target.

13 Aug 2013

Learning "grammar" helps determine whether gene gets switched on or not

Researchers have probed deep into the cell's genome, beyond the basic genetic code, to begin learning the "grammar" that helps determine whether or not a gene gets switched on to make the protein it encodes.

13 Aug 2013

Scientists present novel method to visualize how nuclear protein mobility changes following DNA damage

Understanding the cellular response to DNA strand breaks is crucial to decipher the mechanisms maintaining the integrity of our genome. In eukaryotic cells, the molecular events triggered by DNA damage are strongly influenced by the local chromatin environment surrounding the lesion. The ensuing DNA repair process, in turn, impacts on chromatin structure. In order to understand how these two fundamental processes are mutually connected, both chromatin rearrangements induced by DNA damage as well as DNA repair activity have to be visualized in living cells.

12 Aug 2013

Researchers identify first disease gene for idiopathic focal epilepsy in childhood

More than 50 million people worldwide have epilepsy, with a third of these being children. The most common forms of epilepsy in children occur without any apparent trigger and only affect certain regions of the brain.

12 Aug 2013

Wayne State professor publishes new book that covers advances in nano cell biology

A Wayne State University School of Medicine professor has published a book that covers new advances in nano cell biology, nano medicine and imaging modalities.

12 Aug 2013

Shape and meaning: A study explores how brain encodes visual objects

Opening our eyes and seeing the world before us, full of objects, is a simple action we may take for granted. Yet our brain is constantly carrying out a huge analysis only to let us see a flower, a pen, the face of our children.

12 Aug 2013

Study reveals gray matter atrophy in multiple sclerosis correlated with emotional decline

In multiple sclerosis, gray matter atrophy is extensive, and cognitive deficits and mood disorders are frequently encountered. It has been conjectured that focal atrophy is associated with emotional decline.

12 Aug 2013

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes.

12 Aug 2013

Research: Chronic cocaine use may reduce body's ability to store fat

Chronic cocaine use may reduce the body's ability to store fat, new research from the University of Cambridge suggests. The scientists found that cocaine use may cause profound metabolic changes which can result in dramatic weight gain during recovery, a distressing phenomenon that can lead to relapse.

12 Aug 2013

Study of childhood epilepsies links two new genes to severe forms of disease

A genetic study of childhood epilepsies has linked two new genes to severe forms of disease and provides a novel strategy for identifying therapy targets. This study used a cutting-edge genetic technique, called exome sequencing, to search for new mutations that are not inherited.

12 Aug 2013

Neuroscientists discover protein associated with Alzheimer's Disease

A team of neuroscientists has identified a modification to a protein in laboratory mice linked to conditions associated with Alzheimer's Disease. Their findings, which appear in the journal Nature Neuroscience, also point to a potential therapeutic intervention for alleviating memory-related disorders.

12 Aug 2013

Study shows schizophrenia, bipolar disorder share the most common genetic variation

The largest genome-wide study of its kind has determined how much five major mental illnesses are traceable to the same common inherited genetic variations. Researchers funded in part by the National Institutes of Health found that the overlap was highest between schizophrenia and bipolar disorder; moderate for bipolar disorder and depression and for ADHD and depression; and low between schizophrenia and autism.

12 Aug 2013

Study reveals genetic mutations linked to Parkinson's may play a role in death of brain cells

Researchers have discovered how genetic mutations linked to Parkinson's disease might play a key role in the death of brain cells, potentially paving the way for the development of more effective drug treatments.

12 Aug 2013

Specialized endocytocis play a crucial role in shaping cells themselves

The process cells use to 'swallow' up nutrients, hormones and other signals from their environment - called endocytosis - can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

12 Aug 2013

Medical Science News

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Researchers explore potential of neural stem cells to repair brain damage

Researchers create an efficient technique to target and repair defective genes

Nuevolution forms scientific collaboration to investigate biological mechanism of GPCR drug target

Learning "grammar" helps determine whether gene gets switched on or not

Scientists present novel method to visualize how nuclear protein mobility changes following DNA damage

Researchers identify first disease gene for idiopathic focal epilepsy in childhood

Wayne State professor publishes new book that covers advances in nano cell biology

Shape and meaning: A study explores how brain encodes visual objects

Study reveals gray matter atrophy in multiple sclerosis correlated with emotional decline

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

Research: Chronic cocaine use may reduce body's ability to store fat

Study of childhood epilepsies links two new genes to severe forms of disease

Neuroscientists discover protein associated with Alzheimer's Disease

Study shows schizophrenia, bipolar disorder share the most common genetic variation

Study reveals genetic mutations linked to Parkinson's may play a role in death of brain cells

Specialized endocytocis play a crucial role in shaping cells themselves

Scientists use nanoparticles to regulate DNA interactions in self-assembly, drug-delivery

Researchers identify biomarkers of TB that may help in new treatments

Malvern Instruments to showcase new analytical tools at The Bioprocessing Summit in Boston

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

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