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Combining drugs that target AXL and ErbB receptors could offer better way to fight tumors

Cancer drugs known as ErbB inhibitors have shown great success in treating many patients with lung, breast, colon and other types of cancer. However, ErbB drug resistance means that many other patients do not respond, and even among those who do, tumors commonly come back.

7 Aug 2013

Genetic variations in genes could put patients at risk for statin-associated muscle injury: Study

Statins, a class of drugs used to lower cholesterol, are among the best selling drugs in North America and around the world. However, statin myopathy, which results in muscle pain and weakness, is a common side effect affecting up to 10 percent of statin users. A recent study led by Dr. Richard Kim of the Lawson Health Research Institute, in collaboration with Dr. Robert Hegele of Robarts Research Institute, and researchers from Vanderbilt University, found that commonly occurring genetic variations in a person's genes could put them at risk for statin-associated muscle injury.

7 Aug 2013

UCLA researchers combine cellular and gene therapies to develop treatment for breast cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center have successfully combined cellular therapy and gene therapy in a mouse-model system to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.

7 Aug 2013

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Investigators have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer's disease. A new study published in Restorative Neurology and Neuroscience sheds light on the mechanism underlying aluminum-induced neuronal cell death and identifies necrostatin-1 as a substance which counteracts several of aluminum's neurotoxic effects.

6 Aug 2013

Discovery brings scientists one step closer to understanding challenges linked to mercury cleanup

More forms of mercury can be converted to deadly methylmercury than previously thought, according to a study published Sunday in Nature Geoscience. The discovery provides scientists with another piece of the mercury puzzle, bringing them one step closer to understanding the challenges associated with mercury cleanup.

6 Aug 2013

Study examines genetic overlap between Parkinson disease and Alzheimer disease

A study by Valentina Moskvina, Ph.D., of the Cardiff University School of Medicine, Wales, United Kingdom, and colleagues, examined the genetic overlap between Parkinson disease and Alzheimer disease.

6 Aug 2013

NIH-funded study of aquaporin proteins could hold clues to cataract

Researchers have achieved dynamic, atomic-scale views of a protein needed to maintain the transparency of the lens in the human eye. The work, funded in part by the National Institutes of Health, could lead to new insights and drugs for treating cataract and a variety of other health conditions.

6 Aug 2013

Pupil responses allow communication in locked-in syndrome

Patients who are otherwise completely unable to communicate can answer yes or no questions within seconds with the help of a simple system-consisting of just a laptop and camera-that measures nothing but the size of their pupils.

6 Aug 2013

Study looks at correlation between reading ability and brain structure

A combination of brain scans and reading tests has revealed that several regions in the brain are responsible for allowing humans to read.

6 Aug 2013

CSIRO scientists create broad spectrum coral sunscreen filters

CSIRO, in partnership with skincare company Larissa Bright Australia, has created the world's first UVA/UVB sunscreen filters which mimic the natural sun protection used by corals on the Great Barrier Reef.

6 Aug 2013

Working at clean desk or messy desk may confer its own benefits

Working at a clean and prim desk may promote healthy eating, generosity, and conventionality, according to new research. But, the research also shows that a messy desk may confer its own benefits, promoting creative thinking and stimulating new ideas.

6 Aug 2013

Researchers identify new type of cell in brain that helps people to keep track of their relative location

Using direct human brain recordings, a research team from Drexel University, the University of Pennsylvania, UCLA and Thomas Jefferson University has identified a new type of cell in the brain that helps people to keep track of their relative location while navigating an unfamiliar environment.

6 Aug 2013

Study shows role of love hormone in promoting social and parental bonding

In a loud, crowded restaurant, having the ability to focus on the people and conversation at your own table is critical. Nerve cells in the brain face similar challenges in separating wanted messages from background chatter.

6 Aug 2013

Anti-oxidants have great potential as treatment for neuropathic pain

Neuropathic pain - pain that results from a malfunction in the nervous system - is a daily reality for millions of Americans. Unlike normal pain, it doesn't go away after the stimulus that provoked it ends, and it also behaves in a variety of other unusual and disturbing ways. Someone suffering from neuropathic pain might experience intense discomfort from a light touch, for example, or feel as though he or she were freezing in response to a slight change in temperature.

6 Aug 2013

Novel way to dramatically raise potency of drug candidates targeting RNA

Scientists from the Jupiter campus of The Scripps Research Institute (TSRI) have shown a novel way to dramatically raise the potency of drug candidates targeting RNA, resulting in a 2,500-fold improvement in potency and significantly increasing their potential as therapeutic agents.

6 Aug 2013

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

A team of scientists, led by Napoleone Ferrara, MD, has shown for the first time that a signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy.

6 Aug 2013

Study shows how bioactive component in soy foods plays a role against colon cancer

University of Illinois scientists have evidence that lifelong exposure to genistein, a bioactive component in soy foods, protects against colon cancer by repressing a signal that leads to accelerated growth of cells, polyps, and eventually malignant tumors.

6 Aug 2013

Columbia researchers identify 18 new genes that drive glioblastoma multiforme

A team of researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center has identified 18 new genes responsible for driving glioblastoma multiforme, the most common-and most aggressive-form of brain cancer in adults. The study was published August 5, 2013, in Nature Genetics.

6 Aug 2013

Study: Stem cells in mouth tissue can relieve inflammatory disease

Stem cells found in mouth tissue can not only become other types of cells but can also relieve inflammatory disease, according to a new Ostrow School of Dentistry of USC study in the Journal of Dental Research.

5 Aug 2013

Quick zaps of ultraviolet light can boost vitamin D levels in mushrooms

Quick zaps of ultraviolet light can boost the vitamin D levels in mushrooms in seconds, turning the fungi into an even healthier food, according to Penn State food scientists.

5 Aug 2013

Medical Science News

Combining drugs that target AXL and ErbB receptors could offer better way to fight tumors

Genetic variations in genes could put patients at risk for statin-associated muscle injury: Study

UCLA researchers combine cellular and gene therapies to develop treatment for breast cancer

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Discovery brings scientists one step closer to understanding challenges linked to mercury cleanup

Study examines genetic overlap between Parkinson disease and Alzheimer disease

NIH-funded study of aquaporin proteins could hold clues to cataract

Pupil responses allow communication in locked-in syndrome

Study looks at correlation between reading ability and brain structure

CSIRO scientists create broad spectrum coral sunscreen filters

Working at clean desk or messy desk may confer its own benefits

Researchers identify new type of cell in brain that helps people to keep track of their relative location

Study shows role of love hormone in promoting social and parental bonding

Anti-oxidants have great potential as treatment for neuropathic pain

Novel way to dramatically raise potency of drug candidates targeting RNA

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

Study shows how bioactive component in soy foods plays a role against colon cancer

Columbia researchers identify 18 new genes that drive glioblastoma multiforme

Study: Stem cells in mouth tissue can relieve inflammatory disease

Quick zaps of ultraviolet light can boost vitamin D levels in mushrooms

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

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