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CHOP researchers moving closer to personalized medicine for children with cancer

Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments.

27 Mar 2013

Study suggests possibility of engineering artificial ovaries in lab

A proof-of-concept study suggests the possibility of engineering artificial ovaries in the lab to provide a more natural option for hormone replacement therapy for women.

27 Mar 2013

Study examines specific form of autism caused by duplication on chromosome 15

Identifying and understanding the combination of factors that leads to autism is an ongoing scientific challenge. This developmental disorder appears in the first three years of life, and affects the brain's normal development of social and communication skills.

27 Mar 2013

Study provides important insight into how BMT treatment works in patients with MS

A new study by Multiple Sclerosis researchers at three leading Canadian centres addresses why bone marrow transplantation has positive results in patients with particularly aggressive forms of MS.

27 Mar 2013

Depression also diminish health benefits of physical activities, say researchers

Depression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine.

27 Mar 2013

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Dr. Santosh D'Mello, professor of molecular and cell biology at the University of Texas at Dallas, has received a federal grant for research that may shed light on why and how specific brain cells are affected by Huntington's disease, a devastating, degenerative brain disorder.

27 Mar 2013

Standard formula for calculating LDL cholesterol levels is often inaccurate, study finds

In what promises to be an eye-opener for many doctors and patients who routinely depend on cholesterol testing, a study led by researchers at the Johns Hopkins University School of Medicine found that the standard formula used for decades to calculate low-density lipoprotein cholesterol levels is often inaccurate.

27 Mar 2013

Bladder cancer risk linked to genetic alterations

A new analysis has found that genetic alterations in a particular cellular pathway are linked with bladder cancer risk, recurrence, disease progression, and patient survival. Published early online in CANCER, a peer- reviewed journal of the American Cancer Society, the findings could help improve bladder cancer screening and treatment.

26 Mar 2013

Scientists discover novel compounds that can lead to new strategies for treating diseases

Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.

26 Mar 2013

Researchers re-programme other cells to become nerve cells, directly in the brain

The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments.

26 Mar 2013

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of print in the journal Infection and Immunity.

26 Mar 2013

Organism may cause people to reap more calories from food, contributing to weight gain

How much a person eats may be only one of many factors that determines weight gain. A recent Cedars-Sinai study suggests that a breath test profile of microorganisms inhabiting the gut may be able to tell doctors how susceptible a person is to developing obesity.

26 Mar 2013

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer.

26 Mar 2013

Gladstone investigator to receive Essey Award for fight against amyotrophic lateral sclerosis

Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes, next month will receive the Essey Award for his "Commitment to a Cure" from The ALS Association Golden West Chapter.

26 Mar 2013

New vaccine proves highly effective against H5N1 virus

Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza.

26 Mar 2013

Researchers identify monoclonal antibody that directly kills lymphocytic leukemia cells

Researchers at the University of California, San Diego Moores Cancer Center have identified a humanized monoclonal antibody that targets and directly kills chronic lymphocytic leukemia (CLL) cells.

26 Mar 2013

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone.

26 Mar 2013

Eating behavior could act as defense mechanism against infections and autoimmune disorders

Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections and autoimmune disease development, Yale School of Medicine researchers have found in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

26 Mar 2013

Novel cell therapy effective in treating aggressive form of childhood leukemia

Two children with an aggressive form of childhood leukemia had a complete remission of their disease—showing no evidence of cancer cells in their bodies—after treatment with a novel cell therapy that reprogrammed their immune cells to rapidly multiply and destroy leukemia cells.

26 Mar 2013

Study shows vitamin D can help people breathe better and protect against TB

Maintaining adequate levels of vitamin D can help people breathe better and may even protect against tuberculosis (TB), according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

26 Mar 2013

Medical Science News

CHOP researchers moving closer to personalized medicine for children with cancer

Study suggests possibility of engineering artificial ovaries in lab

Study examines specific form of autism caused by duplication on chromosome 15

Study provides important insight into how BMT treatment works in patients with MS

Depression also diminish health benefits of physical activities, say researchers

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Standard formula for calculating LDL cholesterol levels is often inaccurate, study finds

Bladder cancer risk linked to genetic alterations

Scientists discover novel compounds that can lead to new strategies for treating diseases

Researchers re-programme other cells to become nerve cells, directly in the brain

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

Organism may cause people to reap more calories from food, contributing to weight gain

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Gladstone investigator to receive Essey Award for fight against amyotrophic lateral sclerosis

New vaccine proves highly effective against H5N1 virus

Researchers identify monoclonal antibody that directly kills lymphocytic leukemia cells

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

Eating behavior could act as defense mechanism against infections and autoimmune disorders

Novel cell therapy effective in treating aggressive form of childhood leukemia

Study shows vitamin D can help people breathe better and protect against TB

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