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Study reveals role of SNX27 protein in brain function

What is it about the extra chromosome inherited in Down syndrome-chromosome 21-that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute have new evidence that points to a protein called sorting nexin 27, or SNX27.

25 Mar 2013

LMU researchers identify microRNA that offers promising target for new therapies

Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that plays a prominent role in the process, and offers a promising target for new therapies.

25 Mar 2013

Researchers study how nerve cells repair themselves after injury

One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired at their farthest reaches after injury.

25 Mar 2013

Researchers identify patterns of mutations in early stage node negative lung adenocarcinoma

Molecular driven therapeutic targets have resulted in a paradigm shift in the treatment of advanced lung adenocarcinoma. However, in early non-small cell lung cancer, surgical resection remains the treatment of choice with adjuvant chemotherapy.

25 Mar 2013

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for stimulating protective immune responses following seasonal influenza vaccinations.

25 Mar 2013

Botulism Antitoxin Heptavalent gets FDA approval for patients showing signs of botulism

The U.S. Food and Drug Administration announced today that it has approved Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)-(Equine) to treat patients showing signs of botulism following documented or suspected exposure to botulinum neurotoxin.

25 Mar 2013

Study challenges widely held belief that long nerve grafts do poorly

A study by researchers at Hospital for Special Surgery challenges a widely held belief that long nerve grafts do poorly in adults with an axillary nerve injury. Investigators found that the outcomes of long nerve grafts were comparable to those of modern nerve transfers.

25 Mar 2013

Researchers identify a new approach for treating brain metastases associated with lung cancer

Lung cancer is the world's most common cause of death from cancer. In Austria, around 4,000 people develop this type of cancer every year. One particular problem is the development of brain metastases in association with the lung tumour.

24 Mar 2013

Study of genetically modified immune cells could help improve promising treatment for melanoma

A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer.

24 Mar 2013

Research findings could lead to new therapeutic strategy for heart failure

New research from UC Davis published in the Proceedings of the National Academy of Sciences shows that blocking an enzyme that promotes inflammation can prevent the tissue damage following a heart attack that often leads to heart failure.

24 Mar 2013

Atrophy of thalamus is important predictor of clinically definite MS, study shows

A growing body of research by multiple sclerosis investigators at the University at Buffalo and international partners is providing powerful new evidence that the brain's gray matter reflects important changes in the disease that could allow clinicians to diagnose earlier and to better monitor and predict how the disease will progress.

22 Mar 2013

Translational Research's April issue examines progress, outlook of gene therapy research

The April issue of Translational Research examines the progress and outlook of gene therapy research, with a specific focus on the clinical applicability of gene therapy today.

22 Mar 2013

Two genes associated with rare autism-related disorders linked to general forms of autism: Study

A new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate in general autism research.

22 Mar 2013

ACMG issues recommendations on handling of incidental findings in clinical genome, exome sequencing

In a highly anticipated report, landmark recommendations on the handling of incidental findings in clinical genome and exome sequencing are being issued from the American College of Medical Genetics and Genomics.

22 Mar 2013

Autistic children's brains have reduced connectivity, diminished capacity for neural communication

A new study of patterns of brain communication in toddlers with autism shows evidence of aberrant neural communication even at this relatively early stage of brain development. The results are presented in an article in Brain Connectivity, a bimonthly peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

22 Mar 2013

Scientists find new way to move DNA through cells

Scientists have cracked a 35-year-old mystery about the workings of the natural motors that are serving as models for development of a futuristic genre of synthetic nanomotors that pump therapeutic DNA, RNA or drugs into individual diseased cells.

22 Mar 2013

Last few meals before surgery may affect recovery after surgery, study says

According to a new study, the last few meals before surgery might make a difference in recovery after surgery. Fat tissue is one of the most dominant components that make up the body, and fat tissue is always traumatized during major surgery.

22 Mar 2013

Fralin Life Science Institute researchers use TALENS to alter mosquito genome

Virginia Tech researchers successfully used a gene disruption technique to change the eye color of a mosquito - a critical step toward new genetic strategies aimed at disrupting the transmission of diseases such as dengue fever.

22 Mar 2013

Salk scientists discover how brain keeps track of similar but distinct memories

Ever find yourself racking your brain on a Monday morning to remember where you put your car keys? When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving memories of different environments-such as that room where your keys were hiding in an unusual spot.

22 Mar 2013

Researchers develop new approach for HIV vaccine development

Decades of research and three large-scale clinical trials have so far failed to yield an effective HIV vaccine, in large part because the virus evolves so rapidly that it can evade any vaccine-induced immune response.

22 Mar 2013

Medical Science News

Study reveals role of SNX27 protein in brain function

LMU researchers identify microRNA that offers promising target for new therapies

Researchers study how nerve cells repair themselves after injury

Researchers identify patterns of mutations in early stage node negative lung adenocarcinoma

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Botulism Antitoxin Heptavalent gets FDA approval for patients showing signs of botulism

Study challenges widely held belief that long nerve grafts do poorly

Researchers identify a new approach for treating brain metastases associated with lung cancer

Study of genetically modified immune cells could help improve promising treatment for melanoma

Research findings could lead to new therapeutic strategy for heart failure

Atrophy of thalamus is important predictor of clinically definite MS, study shows

Translational Research's April issue examines progress, outlook of gene therapy research

Two genes associated with rare autism-related disorders linked to general forms of autism: Study

ACMG issues recommendations on handling of incidental findings in clinical genome, exome sequencing

Autistic children's brains have reduced connectivity, diminished capacity for neural communication

Scientists find new way to move DNA through cells

Last few meals before surgery may affect recovery after surgery, study says

Fralin Life Science Institute researchers use TALENS to alter mosquito genome

Salk scientists discover how brain keeps track of similar but distinct memories

Researchers develop new approach for HIV vaccine development

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