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Neuroscientists discover how brain cells form "geotags" for specific memories

Using a video game in which people navigate through a virtual town delivering objects to specific locations, a team of neuroscientists from the University of Pennsylvania and Freiburg University has discovered how brain cells that encode spatial information form "geotags" for specific memories and are activated immediately before those memories are recalled.

29 Nov 2013

Researchers identify gene responsible for malfunctions in fear-related memory system

A study published recently in the Journal of Neuroscience points, for the first time, to the gene trkC as a factor in susceptibility to the disease. The researchers define the specific mechanism for the formation of fear memories which will help in the development of new pharmacological and cognitive treatments.

29 Nov 2013

Body’s natural circadian timing gives performance advantage to West Coast NFL teams at night

A new analysis of National Football League results suggests that the body’s natural circadian timing gives a performance advantage to West Coast teams when they play East Coast teams at night.

28 Nov 2013

Research: Modification of SUMO protein plays vital role in normal brain function

Scientists are a step closer to understanding how some of the brain's 100 billion nerve cells co-ordinate their communication.

28 Nov 2013

Certain Chinese medicines can regulate neurotrophic and apoptosis-related factors

Parkinson's disease is a common neurodegenerative disease in the elderly, which is pathologically characterized by selective loss of dopaminergic neurons. Compound preparations of Chinese medicines that can tonify the kidney have been reported to significantly improve symptoms of Parkinson's disease.

28 Nov 2013

Occludin and connexin 43 expression may reflect pathogenesis of brain injury

Understanding the pathogenesis of brain edema may allow for the prevention and treatment of edema in the field of neurosurgery, thus resulting in better treatments for intracranial diseases.

28 Nov 2013

New injectable therapy could help treat rotator cuff injuries

For a baseball pitcher, a rotator cuff injury often means an extended stay on the disabled list for surgery and rehabilitation of the damaged tendons. But a new technology under development may stop this shoulder injury from becoming so severe that surgery is required.

28 Nov 2013

Optogenetics offers a promising therapy for retinal degeneration

For a few years now optogenetics has been seen as a very promising therapy for progressive blindness, for example when it is a result of retinal degeneration.

28 Nov 2013

Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

A protector for PTEN, a tumor-thwarting protein often missing in cancer cells, has emerged from research led by scientists at The University of Texas MD Anderson Cancer Center published online at Nature Cell Biology this week.

28 Nov 2013

Compound extracted from wine-processed Fructus corni protects hippocampal neurons from damage

Studies have shown that Fructus corni has a protective effect on hepatocytes, and has anticancer, antioxidative, anti-inflammatory and antiseptic properties. 5-hydroxymethylfurfural, a compound extracted from wine-processed Fructus corni, has a protective effect on hippocampal neurons damaged by H2O2.

28 Nov 2013

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Researchers have identified the protein in malaria-causing Plasmodium parasites that is inhibited by a newly discovered class of anti-malarial compounds known as imidazopyrazines.

28 Nov 2013

Accumulation of small protein in brain’s blood vessels can drive early cognitive impairment

A team of Stony Brook University researchers led by William Van Nostrand, PhD, Professor in the Department of Neurosurgery, has discovered in a model of Alzheimer's disease that early accumulation of a small protein, known as amyloid β, in the blood vessels of the brain can drive early cognitive impairment.

28 Nov 2013

NIBIB-funded researchers explore better treatment for brain aneurysms

Thirty thousand Americans suffer severe neurological damage or death from brain aneurysms each year and the existing treatments eventually fail in nearly half of patients. Currently, these "bubbles" in the blood vessel are either clamped off, which requires invasive brain surgery, or filled with platinum coils to induce clotting in the aneurysm. Both treatments, although somewhat effective, can have subsequent problems, including inflammation, incomplete healing, and the development of secondary aneurysms adjacent to the initial site. These complications result in approximately 40 percent of patients needing additional treatment to attempt to re-repair the aneurysm.

28 Nov 2013

Researchers show benefits from testosterone administration in hysterectomized women

Hysterectomy and oophorectomy (the removal of ovaries) are performed to treat various diseases in women, including cancer. These procedures are accompanied not only by a decline in estrogen but also testosterone levels in the blood.

27 Nov 2013

UCLA researchers identify cells involved in placenta development

Dr. Hanna Mikkola and researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have identified a specific type of cell and a related cell communication pathway that are key to the successful growth of a healthy placenta. The findings could greatly bolster our knowledge about the potential causes of complications during pregnancy.

27 Nov 2013

Brain research provides new clues to Pavlovian conditioning

Do fruit flies hold the key to treating dementia? Researchers at the University of Houston have taken a significant step forward in unraveling the mechanisms of Pavlovian conditioning. Their work will help them understand how memories form and, ultimately, provide better treatments to improve memory in all ages.

27 Nov 2013

Findings highlight possible new approach to combat malaria

An international team of scientists, including researchers at Columbia University Medical Center, has identified a key metabolic enzyme that common malaria parasites require for survival at each stage of infection in humans. The findings raise the possibility of a new approach to combating malaria, one of the world's deadliest diseases. The study was published today in the online edition of the journal Nature.

27 Nov 2013

Implantable genetic circuit serves as early warning system for high blood-fat levels

Humankind has a weight problem - and not only in the industrialised nations, either: the growing prosperity in many Asian or Latin American countries goes hand in hand with a way of life that quite literally has hefty consequences.

27 Nov 2013

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These "daughter" cells must be produced at a rate of about one million per second to constantly replenish the body's blood supply.

27 Nov 2013

Bioaxial secures funds to market optical microscopy modules

Bioaxial, developers of super-resolved fluorescence microscopy for the extended imaging of live cells, today announces the completion of a EUR 1.9 million (USD 2.7 million) equity investment by three new large investors; Amorcage Technologique Investissement (a fund managed by CEA Investissement), Inserm Transfert Initiative and Viveris Management plus a range of individual investors.

27 Nov 2013

Medical Science News

Neuroscientists discover how brain cells form "geotags" for specific memories

Researchers identify gene responsible for malfunctions in fear-related memory system

Body’s natural circadian timing gives performance advantage to West Coast NFL teams at night

Research: Modification of SUMO protein plays vital role in normal brain function

Certain Chinese medicines can regulate neurotrophic and apoptosis-related factors

Occludin and connexin 43 expression may reflect pathogenesis of brain injury

New injectable therapy could help treat rotator cuff injuries

Optogenetics offers a promising therapy for retinal degeneration

Enzyme intervenes when cancer-fighting PTEN is bound for cell's protein-destroying machinery

Compound extracted from wine-processed Fructus corni protects hippocampal neurons from damage

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Accumulation of small protein in brain’s blood vessels can drive early cognitive impairment

NIBIB-funded researchers explore better treatment for brain aneurysms

Researchers show benefits from testosterone administration in hysterectomized women

UCLA researchers identify cells involved in placenta development

Brain research provides new clues to Pavlovian conditioning

Findings highlight possible new approach to combat malaria

Implantable genetic circuit serves as early warning system for high blood-fat levels

Study uncovers mechanisms that allow stem cells to keep dividing in perpetuity

Bioaxial secures funds to market optical microscopy modules

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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