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Mutant HSP70i protein may offer potent treatment opportunities for vitiligo

Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune responses in human skin tissue samples.

28 Feb 2013

Reintroducing normal microbial diversity can eliminate VRE from intestinal tracts

Too much antibiotic can decimate the normal intestinal microbiota, which may never recover its former diversity. That, in turn, renders the GI tract vulnerable to being colonized by pathogens. Now researchers from Memorial Sloan-Kettering Cancer Center, New York, NY, and Centro Superior de Investigaci-n en Salud P-blica, Valencia, Spain, show that reintroducing normal microbial diversity largely eliminated vancomycin-resistant enterococci (VRE) from the intestinal tracts of mice..

28 Feb 2013

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production of hyaluronan may be a way to prevent the spreading of cancer.

28 Feb 2013

Researchers identify 25 human proteins that may be crucial for HIV-1 infection and survival

Studying HIV-1, the most common and infectious HIV subtype, Johns Hopkins scientists have identified 25 human proteins "stolen" by the virus that may be critical to its ability to infect new cells. HIV-1 viruses capture many human proteins from the cells they infect but the researchers believe these 25 proteins may be particularly important because they are found in HIV-1 viruses coming from two very different types of infected cells.

28 Feb 2013

Study indicates how gastric bypass reverses diabetes

In a substudy of the STAMPEDE trial (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently), Cleveland Clinic researchers have found that gastric bypass surgery reverses diabetes by uniquely restoring pancreatic function in moderately obese patients with uncontrolled type 2 diabetes.

28 Feb 2013

Scientists identify two populations of human cells that migrate to the intestine

Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD).

28 Feb 2013

Study designs and tests 60 compounds for their ability to kill human cancer cells

Inspired by a chemical that fungi secrete to defend their territory, MIT chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.

28 Feb 2013

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center.

28 Feb 2013

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Scientists at the University of Southampton have taken a significant and important step in keeping people safe from the most common form of meningitis in the UK.

28 Feb 2013

Einstein researchers to investigate consequences of soccer heading on the brain

Sports-related concussion is an increasingly recognized public health problem. At least 1.6 million sports- and recreation-related traumatic brain injuries occur in the United States annually. While the primary focus has been on football, soccer has come under greater scrutiny.

28 Feb 2013

Herceptin may have greater role in treating HER2-negative breast cancer

New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative - and that the drug Herceptin, which targets HER2, may have an even greater role for treating breast cancer and preventing its spread.

28 Feb 2013

ECGs show structural difference in brain connections among children with autism

A look at how the brain processes information finds a distinct pattern in children with autism spectrum disorders. Using EEGs to track the brain's electrical cross-talk, researchers from Boston Children's Hospital have found a structural difference in brain connections. Compared with neurotypical children, those with autism have multiple redundant connections between neighboring brain areas at the expense of long-distance links.

27 Feb 2013

Freie Universität Berlin research team examines thermoresponsive nanogels for treatment of cancer

The German Federal Ministry of Education and Research is supporting a new research group at Freie Universität Berlin that is investigating so-called thermoresponsive nanogels.

27 Feb 2013

Two antagonistic proteins help keep leukemia at bay

Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published in the February 25 issue of Developmental Cell by scientists at Fox Chase Cancer Center.

27 Feb 2013

Study opens possibility for creating animal models of memory disorders

If you ask a rat whether it knows how it came to acquire a certain coveted piece of chocolate, Indiana University neuroscientists conclude, the answer is a resounding, "Yes." A study newly published in the journal Current Biology offers the first evidence of source memory in a nonhuman animal.

27 Feb 2013

Researchers discover that tympanic border cells can enable hearing

Researchers at the Stanford University School of Medicine have identified a group of progenitor cells in the inner ear that can become the sensory hair cells and adjacent supporting cells that enable hearing.

27 Feb 2013

New findings could help develop treatments for inherited disorders

Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders.

27 Feb 2013

Promyleocytic leukemia gene goes up significantly in post treatment of mTOR inhibitors

Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell growth and drug resistance, they are discovering molecular pathways that might lead to new targeted therapies to potentially treat this deadly cancer.

27 Feb 2013

Surgical site infections appear to have significant genetic connections

An estimated 300,000 U.S. patients get surgical site infections every year, and while the causes are varied, a new University of Utah study suggests that some who get an infection can blame it partly on their genes.

27 Feb 2013

High iron and zinc intake may reduce risk of pre-menstrual syndrome in women

Women who reported eating a diet rich in iron were 30 to 40 percent less likely to develop pre-menstrual syndrome (PMS) than women who consumed lower amounts, in a study reported this week by researchers at the University of Massachusetts Amherst School of Public Health and Health Sciences and Harvard.

27 Feb 2013

Medical Science News

Mutant HSP70i protein may offer potent treatment opportunities for vitiligo

Reintroducing normal microbial diversity can eliminate VRE from intestinal tracts

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

Researchers identify 25 human proteins that may be crucial for HIV-1 infection and survival

Study indicates how gastric bypass reverses diabetes

Scientists identify two populations of human cells that migrate to the intestine

Study designs and tests 60 compounds for their ability to kill human cancer cells

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Einstein researchers to investigate consequences of soccer heading on the brain

Herceptin may have greater role in treating HER2-negative breast cancer

ECGs show structural difference in brain connections among children with autism

Freie Universität Berlin research team examines thermoresponsive nanogels for treatment of cancer

Two antagonistic proteins help keep leukemia at bay

Study opens possibility for creating animal models of memory disorders

Researchers discover that tympanic border cells can enable hearing

New findings could help develop treatments for inherited disorders

Promyleocytic leukemia gene goes up significantly in post treatment of mTOR inhibitors

Surgical site infections appear to have significant genetic connections

High iron and zinc intake may reduce risk of pre-menstrual syndrome in women

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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