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Two studies discover new enzyme that acts as a sensor of innate immunity

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.

16 Feb 2013

Researchers develop nano-machines that recreate principal activities of proteins

Physicists of the University of Vienna together with researchers from the University of Natural Resources and Life Sciences Vienna developed nano-machines which recreate principal activities of proteins.

16 Feb 2013

Colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome

Cleveland Clinic researchers have found that colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome, the most common hereditary, adult-onset cause of colorectal cancer, as published in the online version of the Journal of Clinical Oncology.

16 Feb 2013

Researchers create new ultra-sensitive tool for chemical, DNA and protein analysis

Utilizing optical characteristics first demonstrated by the ancient Romans, researchers at the University of Illinois at Urbana-Champaign have created a novel, ultra-sensitive tool for chemical, DNA, and protein analysis.

16 Feb 2013

'Vaccine patch' could make immunizations cheaper, easier

"An innovative new way to deliver vaccines could drastically improve the health of the third world, and even the first world, by making vaccines cheaper and easier to distribute and use," Business Insider reports, adding, "The 'vaccine patch' would be as easy to apply as a Band-Aid, and would be stable for weeks at room temperature."

16 Feb 2013

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Microbes present in the gut can affect the severity of kidney disease brought on by melamine poisoning, according to an international study led by Professor Wei Jia at the University of North Carolina in collaboration with the research group of Professor Jeremy Nicholson at Imperial College London.

16 Feb 2013

Parkinson's-related mutations may also affect vision

The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.

16 Feb 2013

Researchers identify mechanism through which mitochondria control breast tumor aggressiveness

Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode-an issue with profound implications for treatment. Now a group from The Scripps Research Institute (TSRI) has identified a mechanism through which mitochondria, the powerhouses of a cell, control tumor aggressiveness.

16 Feb 2013

Spherical nucleic acids could revolutionize biomedicine

Northwestern University's Chad A. Mirkin, a world-renowned leader in nanotechnology research and its application, has invented and developed a powerful material that could revolutionize biomedicine: spherical nucleic acids (SNAs).

16 Feb 2013

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.

16 Feb 2013

Study finds little long-term survival advantage for women with ovarian cancer and BRCA mutations

Researchers at Moffitt Cancer Center and colleagues in Toronto and at Yale University studied the long-term survival of women with a BRCA1 or BRCA2 gene mutation who were diagnosed with invasive ovarian cancer. They found that the short-term benefit to having either mutation does not lead to a long-term survival benefit.

16 Feb 2013

New approach could make gene therapy dramatically more effective for HIV patients

A research team from Case Western Reserve University School of Medicine has discovered an approach that could make gene therapy dramatically more effective for patients.

16 Feb 2013

Tau release from healthy neurons can be regulated by neuronal activity

Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death.

16 Feb 2013

Emory receives NINDS grant for biomarker research on Parkinson's

The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a three-year, $900,000 grant to the Center for Biomedical Imaging Statistics at Emory's Rollins School of Public Health.

16 Feb 2013

Prions may be crucial in brain development during childhood

A molecule that is not only dangerous, but can help the brain grow. A few years ago it was found that certain proteins, the prions, when defective are dangerous, as they are involved in neurodegenerative syndromes such as the Creutzfeldt-Jakob and the Alzheimer diseases.

16 Feb 2013

Canine Pompe disease can now be diagnosed with genetic test

Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans. Based on this finding, canine Pompe disease can now be diagnosed with a genetic test.

16 Feb 2013

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

Recent studies have identified correlations between cigarette smoke-induced microRNA (miRNA) expression and different aspects of lung cancer; however, it is unclear how miRNA expression directly contributes to carcinogenesis.

16 Feb 2013

Diabetes increases mortality after myocardial infarction by oxidizing CaMKII enzyme

Diabetic patients are more than twice as likely to die from a heart attack as non-diabetic patients, but the mechanisms that underlie increased heart attack-related mortality in diabetic patients are unknown. High levels of the oxidized form of the protein CamKII (ox-CaMKII) have been linked to increased risk of sudden death after heart attack.

16 Feb 2013

'Primitive' reflexes may involve more sophisticated brain function than previously thought

Supposedly 'primitive' reflexes may involve more sophisticated brain function than previously thought, according to researchers at Imperial College London.

16 Feb 2013

IKBKE gene plays a key role in tobacco-induced lung cancer

Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response.

16 Feb 2013

Medical Science News

Two studies discover new enzyme that acts as a sensor of innate immunity

Researchers develop nano-machines that recreate principal activities of proteins

Colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome

Researchers create new ultra-sensitive tool for chemical, DNA and protein analysis

'Vaccine patch' could make immunizations cheaper, easier

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Parkinson's-related mutations may also affect vision

Researchers identify mechanism through which mitochondria control breast tumor aggressiveness

Spherical nucleic acids could revolutionize biomedicine

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Study finds little long-term survival advantage for women with ovarian cancer and BRCA mutations

New approach could make gene therapy dramatically more effective for HIV patients

Tau release from healthy neurons can be regulated by neuronal activity

Emory receives NINDS grant for biomarker research on Parkinson's

Prions may be crucial in brain development during childhood

Canine Pompe disease can now be diagnosed with genetic test

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

Diabetes increases mortality after myocardial infarction by oxidizing CaMKII enzyme

'Primitive' reflexes may involve more sophisticated brain function than previously thought

IKBKE gene plays a key role in tobacco-induced lung cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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