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Researchers show how modern science can unlock mysteries of the past

Two teams of Michigan State University researchers - one working at a medieval burial site in Albania, the other at a DNA lab in East Lansing - have shown how modern science can unlock the mysteries of the past.

4 Jan 2012

Osiris provides update on Prochymal Phase 2 trial for type 1 diabetes

Osiris Therapeutics, Inc., today provided an update on its Phase 2 trial evaluating Prochymal, a formulation of adult mesenchymal stem cells (MSCs), in patients with newly diagnosed type 1 diabetes.

4 Jan 2012

Researchers identify gene required for proper development of mouse inner ear

Providing clues to deafness, researchers at Washington University School of Medicine in St. Louis have identified a gene that is required for proper development of the mouse inner ear.

4 Jan 2012

MRC-funded study to explore pancreatic cancer

A promising line of attack against pancreatitis and pancreatic cancer is to be explored further at Cardiff University, thanks to substantial new funding from the Medical Research Council.

4 Jan 2012

Scientists discover chemical compound that inhibits poxviruses from replicating

A team of scientists from Boston University School of Medicine (BUSM) have identified a novel compound that inhibits viruses from replicating. The findings, which are published online in the Journal of Virology, could lead to the development of highly targeted compounds to block the replication of poxviruses, such as the emerging infectious disease Monkeypox.

4 Jan 2012

Mitochondrial dysfunction in tissue stem cells can cause aging-associated degeneration

Aging-related tissue degeneration can be caused by mitochondrial dysfunction in tissue stem cells. The research group of Professor Anu Suomalainen Wartiovaara at the University of Helsinki, with their collaborators in Max Planck Institute for Biology of Aging, Karolinska Institutet and University of Wisconsin, reported on the 3rd January in Cell Metabolism their results on mechanisms of aging-associated degeneration.

4 Jan 2012

Hydrogen sulfide decreases manufacture of kidney scarring matrix proteins

Hydrogen sulfide, a gas notorious for its rotten-egg smell, may have redeeming qualities after all. It reduces high glucose-induced production of scarring proteins in kidney cells, researchers from The University of Texas Health Science Center San Antonio report in the Journal of Biological Chemistry.

4 Jan 2012

Protein increases lean mass while extra calories increase fat mass

In a study conducted among 25 healthy individuals living in a controlled setting who were randomized to overconsumption of different levels of protein diets, those consuming the low-protein diet had less weight gain compared to those consuming normal and high protein diets, and calories alone, and not protein appeared to contribute to an increase in body fat, according to a study in the January 4 issue of JAMA.

4 Jan 2012

Woman's ovarian cycle plays an important role in her susceptibility to infection

A new research report in the Journal of Leukocyte Biology suggests that a woman's ovarian cycle plays an important role in her susceptibility to infection.

4 Jan 2012

Origin of osteoporosis could be directly linked to manganese depletion

The loss of manganese could mean that calcium does not stick to bones and could cause osteoporosis. This is the new theory put forward by researchers at the University of Castilla-La Mancha (UCLM) in Spain after studying deer antlers.

3 Jan 2012

TrovaGene acquires license to mutations of SF3B1 splicing factor in CLL

TrovaGene, Inc., a developer of trans-renal molecular diagnostics, today announced that it has obtained an exclusive worldwide license to mutations of the SF3B1 splicing factor, which have been shown to be associated with disease progression and chemotherapy response in patients suffering from chronic lymphocytic leukemia.

3 Jan 2012

Combination of biomarkers indicates high risk of Alzheimer's in the future

Physician Oskar Hansson and his research group are studying biomarkers - substances present in spinal fluid and linked to Alzheimer's disease. The group has studied close to 140 people with mild memory impairment, showing that a certain combination of markers (low levels of the substance beta-amyloid and high levels of the substance tau) indicate a high risk of developing Alzheimer's disease in the future.

3 Jan 2012

Adiponectin may play a role in development of all-cause dementia and AD in women

A hormone derived from visceral fat called adiponectin may play a role as a risk factor for development of all-cause dementia and Alzheimer disease (AD) in women, according to a study published Online First by the Archives of Neurology, one of the JAMA/Archives journals.

3 Jan 2012

Marijuana ingredients appear to affect regional brain function during salience processing

Different ingredients in marijuana appear to affect regions of the brain differently during brain processing functions involving responses to certain visual stimuli and tasks, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

3 Jan 2012

Adolescents diagnosed with schizophrenia appear to show greater brain GM volume loss

Adolescents diagnosed with schizophrenia and other psychoses appear to show greater decreases in gray matter volume and increases in cerebrospinal fluid in the frontal lobe compared to healthy adolescents without a diagnosis of psychosis, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

3 Jan 2012

Scientists show how HCV virus hijacks miR-122 in liver cells

Viral diseases are still one of the biggest challenges to medical science. Thanks to thousands of years of co-evolution with humans, their ability to harness the biology of their human hosts to survive and thrive makes them very difficult to target with medical treatment.

2 Jan 2012

CSF Aβ42 levels appear to be decreased before patients with MCI develop AD dementia

Cerebrospinal fluid levels of Aβ42 appear to be decreased at least five to 10 years before some patients with mild cognitive impairment develop Alzheimer disease (AD) dementia whereas other spinal fluid levels seem to be later markers of disease, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Jan 2012

Van Andel studies distinguish cancer subtypes and provide promising new drug targets

Two recent studies by Van Andel Research Institute scientists are providing a foundation for a more complete understanding of distinct kidney cancer subtypes, which could pave the way for better treatments.

30 Dec 2011

Chimps, like humans, inform ignorant group members of danger

It's a basic rule of effective communication: Consider your audience. According to a new report published online on December 29 in Current Biology, a Cell Press publication, that rule of thumb is not lost on wild chimpanzees. Chimps are more likely to make an alarm call about the presence of a snake when others in the group are unaware of the apparent danger they face, the new evidence shows.

30 Dec 2011

Glia cells also regulate learning and memory

Glia cells, named for the Greek word for "glue," hold the brain's neurons together and protect the cells that determine our thoughts and behaviors, but scientists have long puzzled over their prominence in the activities of the brain dedicated to learning and memory.

30 Dec 2011

Medical Science News

Researchers show how modern science can unlock mysteries of the past

Osiris provides update on Prochymal Phase 2 trial for type 1 diabetes

Researchers identify gene required for proper development of mouse inner ear

MRC-funded study to explore pancreatic cancer

Scientists discover chemical compound that inhibits poxviruses from replicating

Mitochondrial dysfunction in tissue stem cells can cause aging-associated degeneration

Hydrogen sulfide decreases manufacture of kidney scarring matrix proteins

Protein increases lean mass while extra calories increase fat mass

Woman's ovarian cycle plays an important role in her susceptibility to infection

Origin of osteoporosis could be directly linked to manganese depletion

TrovaGene acquires license to mutations of SF3B1 splicing factor in CLL

Combination of biomarkers indicates high risk of Alzheimer's in the future

Adiponectin may play a role in development of all-cause dementia and AD in women

Marijuana ingredients appear to affect regional brain function during salience processing

Adolescents diagnosed with schizophrenia appear to show greater brain GM volume loss

Scientists show how HCV virus hijacks miR-122 in liver cells

CSF Aβ42 levels appear to be decreased before patients with MCI develop AD dementia

Van Andel studies distinguish cancer subtypes and provide promising new drug targets

Chimps, like humans, inform ignorant group members of danger

Glia cells also regulate learning and memory

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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