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Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

New test could predict life-threatening side effects of cancer immunotherapy

Medical researchers in Japan have discovered a way to predict a potentially life-threatening side effect of cancer immunotherapy before it occurs.

10 Mar 2025

Can eating invasive species and forgotten crops boost Europe's food security?

European researchers propose diversifying diets with novel foods (NF), underutilized crops (NUS), and invasive species (IAS) to combat biodiversity loss and food insecurity, balancing ecological benefits with risks like regulatory barriers and consumer skepticism.

10 Mar 2025

Compound found in rosemary shows promise for Alzheimer's treatment

The herb rosemary has long been linked with memory: "There's rosemary, that's for remembrance," says Ophelia in Shakespeare's Hamlet. So it is fitting that researchers would study a compound found in rosemary and sage-carnosic acid-for its impact on Alzheimer's disease.

10 Mar 2025

Cordycepin helps tired mice run longer and think better, study finds

Researchers show that cordycepin, a compound from Cordyceps militaris, can boost endurance and protect brain function in mice exhausted by excessive exercise.

10 Mar 2025

Canary in the coalmine: Study warns 21 million children missed measles shots in 2022

Researchers found that 21 million children missed measles vaccination in 2022, far exceeding those missing other vaccines, and 96% were in low- and middle-income countries. The study urges adding measles vaccination rates to global definitions of under-immunized children to better prevent deadly outbreaks.

10 Mar 2025

How falling measles vaccination rates put millions of children at risk

Two-dose measles vaccination coverage has fallen by 3.7% globally since 2019, leaving most WHO regions off track to meet Immunization Agenda 2030 targets. The study highlights a worrying rise in zero-dose children, especially in Africa, threatening global herd immunity against measles.

10 Mar 2025

Is red meat good or bad for you? Study explains how amino acids shape the answer

Researchers at Texas Tech University reviewed how red meat proteins and amino acids affect human health, weighing both benefits and risks. Their findings highlight that while red meat provides vital nutrients, overconsumption and poor preparation methods can increase disease risk.

10 Mar 2025

Scientists discover key molecular switch for blood stem cell regeneration

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators.

10 Mar 2025

New stem cell-based vascular grafts could revolutionize cardiac surgery

Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998.

10 Mar 2025

Study delves into the role of SOX9 in hypospadias development

Hypospadias is a widespread congenital disorder, characterized by an abnormal placement of the urethral opening, impacting as many as 3.42% of male children worldwide. Beyond the physical consequences, this condition can lead to psychological and fertility issues.

10 Mar 2025

Research sheds light on human misperceptions of dog emotions

Life with a dog is a matter of give and take. Especially when it comes to communication. With no common human-dog language, our ability to communicate relies on understanding and reading our pet, and vice versa.

10 Mar 2025

Exploring the causal links among immune cells, inflammatory proteins, and aortic dissection

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection is a life-threatening condition with complex immunological underpinnings.

10 Mar 2025

Restoring gut health in ulcerative colitis through microbiome-based therapy

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health.

10 Mar 2025

Low semen quality linked to shorter lifespan

Researchers determine how low semen quality may impact mortality risk.

10 Mar 2025

Why do some people need supplements and others don’t? New review explains

New research in The New England Journal of Medicine reviews current knowledge on micronutrient requirements, deficiencies, and interventions. It highlights the need for targeted supplementation and calls for advanced research to better diagnose and treat hidden deficiencies.

9 Mar 2025

How to pick healthier gluten-free bread

Gluten-free (GF) breads and flours often contain less natural fiber and more fat than gluten-containing counterparts, with added psyllium or gums boosting fiber at the cost of higher saturated fats. Researchers urge better formulation to match GF diets’ nutritional quality to traditional options.

9 Mar 2025