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Structural biology uncovers the molecular basis of b1 vitamin transport and deficiency

Vitamin B1, also known as thiamine, is essential for the survival of our cells. The human body can't produce it, but we can maintain healthy levels of this vitamin by eating foods like salmon, legumes, and brown rice.

16 Oct 2024

Antiverse raises £3.5 M ($4.6 M) to advance generative AI antibody design platform

Antiverse, a techbio company designing antibodies for challenging targets, today announced it has added £3.5 M ($4.6 M) to its seed funding.

From Antiverse 16 Oct 2024

Alleo and Ubiquigent enter AI-driven strategic partnership to accelerate DUB-focused drug discovery

Ubiquigent Limited (“Ubiquigent”), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced a strategic partnership with Alleo Labs Corp. (“Alleo”), a pioneer in using artificial intelligence (AI) to develop new therapeutics for neurological diseases.

From Ubiquigent Limited 16 Oct 2024

Gene editing restores treatment sensitivity in melanoma

In a potential advance for melanoma patients, researchers at ChristianaCare’s Gene Editing Institute have used CRISPR gene editing tools to disable a gene mutation often seen in aggressive forms of this dangerous skin cancer that renders promising treatments ineffective.

16 Oct 2024

Everyday products ranked for health impact: Which ones are harming you and which are making you healthier?

The Building H Index 2024 rates 75+ non-healthcare products on their impact on human health, identifying how daily-use items influence eating, sleep, physical activity, social interaction, and outdoor behaviors. The report pushes for company accountability in improving health outcomes through small product modifications.

16 Oct 2024

Historical review reveals French contributions to depression research

In an era where mental health awareness is at the forefront of public discourse, a new historical review is shedding light on the often-overlooked French contributions to our understanding of depression.

16 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

DNA changes from high potency cannabis use may signal psychosis risk

Published in Molecular Psychiatry, this is the first study to suggest that the use of high potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of cannabis use.

15 Oct 2024

Distinct immune profiles linked to adverse reactions from immunotherapy

Distinct immune "signatures" in patients who develop adverse events while taking immunotherapy for cancer may help oncologists identify patients at risk and treat them early to prevent serious side effects, suggests a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

15 Oct 2024

Yeast discovery offers new insights into cancer survival

The discovery of a surprising way yeast used to brew beer can survive starvation could open the door to new treatments for cancer.

15 Oct 2024

New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024

COVID-19 raises the risk of type 2 diabetes in children, study reveals

Researchers found that children who contracted COVID-19 were at a higher risk of developing type 2 diabetes within six months, compared to those with other respiratory infections.

15 Oct 2024

New insights into pain mechanisms related to viral infections

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it.

15 Oct 2024

Genetics identified as key factor in gout development

A major international study has found gout is a chronic illness where genetics is a major cause, rather than lifestyle choices of the sufferer.

15 Oct 2024

Study reveals how Alzheimer's may cause brain damage in two distinct phases

Alzheimer's disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

15 Oct 2024

Understanding how the hippocampus discriminates social threat from safety

How do we distinguish threat from safety? It's a question important not just in our daily lives, but for human disorders linked with fear of others, such as social anxiety or post-traumatic stress disorder (PTSD).

15 Oct 2024

Experimental drug RK-33 shows promise in treating breast cancer bone metastasis

In a new study led by Johns Hopkins Medicine, the drug RK-33 has demonstrated promise in treating breast cancer that has spread to the bone (breast cancer bone metastasis). RK-33 was previously shown to help treat other types of cancer and viral illnesses.

15 Oct 2024