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Researchers discover new inherited disorder that causes mental retardation, liver dysfunction

Researchers at the Swedish medical university Karolinska Institutet have discovered a new inherited disorder that causes severe mental retardation and liver dysfunction. The disease, adenosine kinase deficiency, is caused by mutations in the ADK gene, which codes for the enzyme adenosine kinase.

1 Oct 2011

Study demonstrates how the intestine maintains 'immune tolerance' under healthy conditions

Imagine a single drug that would treat most, if not all, autoimmune disorders, such as asthma, inflammatory bowel disease, and Lupus. That might not be so hard to do thanks to a team of researchers who have discovered a molecule normally used by the body to prevent unnecessary immune reactions.

30 Sep 2011

The 7th annual World Stem Cell Summit takes place in Pasadena, CA

Stem cell research and regenerative medicine has long held the potential to treat serious medical conditions, but only recently has the industry as a whole begun to take shape. What was once confined within the realm of research and academia is now attracting the interest of corporations and philanthropists who are investing large amounts of money into this promising science.

30 Sep 2011

New targeting approach to develop an active site-directed, drug-like PTP1B inhibitor

The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes and obesity from being addressed successfully by novel drugs.

30 Sep 2011

Fat-rich 'western diet' fuels cardiovascular disease, type 2 diabetes and obesity

A major risk factor for cardiovascular disease, type 2 diabetes and other health- and life-threatening conditions, obesity is epidemic in the United States and other developed nations where it's fueled in large part by excessive consumption of a fat-rich "Western diet."

30 Sep 2011

Free radical peroyxnitrite linked to failure of cytotoxic T-cells to eliminate tumors

Researchers at the Moffitt Cancer Center in Tampa, Fla., and colleagues have found that tumor cell resistance to a specific cancer immunotherapy designed to kill cancer cells can be blamed on a mechanism that involves the production of a free radical peroxynitrite (PNT) that causes resistance to therapeutic cancer-killing cells.

30 Sep 2011

Estradiol plays an important role in several metabolic diseases

Hormone researchers at the University of Houston (UH) have their sights set on providing long-term treatment options for diabetes, obesity and cardiovascular diseases by better understanding estradiol, the most potent naturally occurring estrogen.

30 Sep 2011

UCLA scientists create mouse model for autism

UCLA scientists have created a mouse model for autism that opens a window into the biological mechanisms that underlie the disease and offers a promising way to test new treatment approaches.

30 Sep 2011

ALK gene discovered by St. Jude scientists associated with FDA approved adult cancer drug

A drug recently approved by the U.S. Food and Drug Administration for treatment of an adult cancer targets a malfunctioning gene discovered more than a decade earlier at St. Jude Children's Research Hospital. The story highlights how scientific findings from St. Jude can be translated into therapies and tests that in addition to helping children, also help adults.

30 Sep 2011

AnaptysBio awarded DARPA contract extension for additional high affinity thermally stable antibodies

AnaptysBio, Inc., a privately-held therapeutic antibody company, today announced that the Defense Advanced Research Projects Agency (DARPA) has extended its contract with AnaptysBio to generate additional high affinity thermally stable antibodies for biodefense applications. This extension was awarded based upon the successful completion by AnaptysBio of milestones during the first year of the contract.

30 Sep 2011

Researchers use fMRI to examine patterns of brain activation in patients with chronic pain

Cognition is known to influence pain perception. As a result, several mind-body and psychological therapies are commonly used to treat chronic pain. A new study from the October issue of Anesthesiology analyzed whether two of the most commonly applied strategies involve different brain systems.

30 Sep 2011

Researchers develop HTGTS to map translocatome in the genome

Researchers at Children's Hospital Boston and the Immune Disease Institute (IDI) have created a method for mapping "hot spots" in the genome where chromosomes are most likely to break and recombine, knowledge that helps define the rules that govern when and where breaks occur.

30 Sep 2011

Researchers discover 'superfast' muscles in mammals for the first time

As nocturnal animals, bats rely echolocation to navigate and hunt prey. By bouncing sound waves off objects, including the bugs that are their main diet, bats can produce an accurate representation of their environment in total darkness. Now, researchers at the University of Southern Denmark and the University of Pennsylvania have shown that this amazing ability is enabled by a physical trait never before seen in mammals: so-called "superfast" muscles.

30 Sep 2011

Two ACS members, editor of JACS to receive nation's highest honors in science and innovation

Peter J. Stang, Ph.D., editor of the Journal of the American Chemical Society (JACS), and American Chemical Society members Jacqueline K. Barton, Ph.D. and Rakesh Agrawal, Ph.D., are among 12 eminent researchers and inventors named by President Obama to receive the nation's highest honors in science and innovation.

30 Sep 2011

Three Georgia Tech projects to receive NSF's EFRI grants

The National Science Foundation (NSF) has awarded $6 million to fund three projects involving researchers from the Georgia Institute of Technology. Each four-year, $2 million grant was awarded through the NSF's Division of Emerging Frontiers in Research and Innovation.

30 Sep 2011

Immunotherapeutics for treatment of metastatic melanoma

A new cancer research program at Loyola University Chicago Stritch School of Medicine will develop therapies designed to turn patients' own immune systems into potent weapons against cancer.

30 Sep 2011

Researchers determine structure of RIG-I protein linked with viral infections

Researchers at Rutgers and UMDNJ-Robert Wood Johnson Medical School have determined the structure of a protein that is the first line of defense in fighting viral infections including influenza, hepatitis C, West Nile, rabies, and measles.

30 Sep 2011

UNC professor wins 2011 PECASE award for research into alcohol addiction

During a White House ceremony next month, Thomas L. Kash, PhD, assistant professor in the department of pharmacology and the UNC Bowles Center for Alcohol Studies at the University of North Carolina at Chapel Hill School of Medicine will receive the Presidential Early Career Award for Scientists and Engineers.

30 Sep 2011

Two UTA scientists win 2011 PECASE award for innovative research

Two scientists from The University of Texas at Austin are among the 2011 recipients of Presidential Early Career Awards for Scientists and Engineers (PECASE), the highest honor bestowed by the United States government on science and engineering professionals in the early stages of their independent research careers.

30 Sep 2011

Homobrassinolide may increase appetite, muscle mass and physical performance

New research in The FASEB Journal suggests that rats fed homobrassinolide, found in the mustard plant, produced an anabolic effect, and increased appetite and muscle mass, as well as the number and size of muscle fibers.

30 Sep 2011

Medical Science News

Researchers discover new inherited disorder that causes mental retardation, liver dysfunction

Study demonstrates how the intestine maintains 'immune tolerance' under healthy conditions

The 7th annual World Stem Cell Summit takes place in Pasadena, CA

New targeting approach to develop an active site-directed, drug-like PTP1B inhibitor

Fat-rich 'western diet' fuels cardiovascular disease, type 2 diabetes and obesity

Free radical peroyxnitrite linked to failure of cytotoxic T-cells to eliminate tumors

Estradiol plays an important role in several metabolic diseases

UCLA scientists create mouse model for autism

ALK gene discovered by St. Jude scientists associated with FDA approved adult cancer drug

AnaptysBio awarded DARPA contract extension for additional high affinity thermally stable antibodies

Researchers use fMRI to examine patterns of brain activation in patients with chronic pain

Researchers develop HTGTS to map translocatome in the genome

Researchers discover 'superfast' muscles in mammals for the first time

Two ACS members, editor of JACS to receive nation's highest honors in science and innovation

Three Georgia Tech projects to receive NSF's EFRI grants

Immunotherapeutics for treatment of metastatic melanoma

Researchers determine structure of RIG-I protein linked with viral infections

UNC professor wins 2011 PECASE award for research into alcohol addiction

Two UTA scientists win 2011 PECASE award for innovative research

Homobrassinolide may increase appetite, muscle mass and physical performance

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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