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DSMB authorizes ACT to proceed with next set of patients in stem cell clinical trials

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today that the independent Data and Safety Monitoring Board (DSMB) overseeing the Company's two ongoing stem cell clinical trials in the United States authorized ACT to move forward with enrolling and treating the next set of patients in each of the trials.

29 Sep 2011

UCSF scientists identify how normal cells transform into brain tumors

Brain tumor specimens taken from neurosurgery cases at the University of California, San Francisco (UCSF) Medical Center has given scientists a new window on the transformation that occurs as healthy brain cells begin to form tumors.

29 Sep 2011

Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

Genetic variant may increase severity of coronary artery disease in patients with diabetes

Researchers at Washington University School of Medicine in St. Louis have identified the first genetic variant associated with severity of coronary artery disease in patients with type 2 diabetes.

29 Sep 2011

Researchers identify 'programmed cell death' pathway in parasitic worms

Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's most serious and prevalent diseases.

29 Sep 2011

Researchers discover kibra protein controls sculpting of brain circuitry

Researchers working with adult mice have discovered that learning and memory were profoundly affected when they altered the amounts of a certain protein in specific parts of the mammals' brains.

29 Sep 2011

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.

29 Sep 2011

Simple low-cost method for isolation and collection of fragile prostate cancer cells

At the Oct. 2-6 microTAS 2011 conference, the premier international event for reporting research in microfluidics, nanotechnology and detection technologies for life science and chemistry, University of Cincinnati researchers will present a simple, low-cost, method for separating and safely collecting concentrated volumes of fragile prostate cancer cells.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Salk Institute professor named 2011 recipient of NIH Director's T-R01 program

Dr. Fred Gage, a professor in the Salk Institute Laboratory of Genetics and holder of the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Diseases, has been named a 2011 recipient of the prestigious National Institutes of Health (NIH) Director's Transformative Research Projects (T-R01) program.

29 Sep 2011

Older women destined to develop AD have high blood levels of pregnancy protein

In an advance toward a much-needed early diagnostic test for Alzheimer's disease (AD), scientists have discovered that older women destined to develop AD have high blood levels of a protein linked to pregnancy years before showing symptoms.

29 Sep 2011

Prototype drug shows promise against chronic lymphocytic leukemia

Pre-clinical research has generated some very promising findings about a prototype drug for the treatment of chronic lymphocytic leukemia.

29 Sep 2011

Acetyl-L-carnitine likely to improve outcomes and recovery for individuals with SCI

A commonly used supplement is likely to improve outcomes and recovery for individuals who sustain a spinal cord injury (SCI), according to research conducted by University of Kentucky neuroscientists.

29 Sep 2011

Johns Hopkins researchers discover oxaliplatin-based nerve damage

Oxaliplatin, a platinum-based anticancer drug that's made enormous headway in recent years against colorectal cancer, appears to cause nerve damage that may be permanent and worsens even months after treatment ends.

29 Sep 2011

Scientists discover effective target to kill late-stage metastatic prostate cancer cells

Purdue University scientists believe they have found an effective target for killing late-stage, metastatic prostate cancer cells.

29 Sep 2011

First developmental study of human neural stem cells in subventricular zone

Researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center have identified a new pathway of stem cell activity in the brain that represents potential targets of brain injuries affecting newborns.

29 Sep 2011

Yale researchers use AB SCIEX's QTRAP technology to synthesize phosphoproteins

AB SCIEX, a global leader in life science analytical technologies, today announced that Yale University researchers used QTRAP technology to prove the validity of a new approach to synthesize phosphoproteins.

28 Sep 2011

Applied Biomics adds iTRAQ service to its proteomics line

Applied Biomics, Inc., a leading Proteomics service provider, is pleased to announce the addition of iTRAQ service (Isobaric Tags for Relative and Absolute Quantitation) to its proteomics line.

28 Sep 2011

University of Utah organic chemist wins National Medal of Science

University of Utah organic chemist Peter J. Stang has won a National Medal of Science - the highest U.S. honor for a scientist or engineer - and is tentatively scheduled to be honored by President Barack Obama at the White House later this year.

28 Sep 2011

Some stroke patients may benefit from treatment outside the typical 3 hour window

Stroke victims may have a longer window of opportunity to receive treatment to save their brain cells, demonstrates a literature review published by University of Alberta medical researchers in Lancet Neurology.

28 Sep 2011