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Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast cancer and other tumor types.

2 Dec 2011

Life as a couch potato can create new fat in fat cells

Conventional wisdom says that exercise is a key to weight loss - a no-brainer. But now, Tel Aviv University researchers are revealing that life as a couch potato, stretched out in front of the TV, can actually be "active inactivity" - and cause you to pack on the pounds.

2 Dec 2011

Body's surveillance for cancer causing damage and response to allergies share common pathway

CANCER RESEARCH UK scientists have found that the body's surveillance for cancer causing damage and its response to allergies share a common pathway, according to research published in Science on Thursday.

1 Dec 2011

Insights into causes of Idiopathic Pulmonary Fibrosis

Tracking individual cells within the lung as they move around and multiply has given Duke University researchers new insights into the causes of Idiopathic Pulmonary Fibrosis (IPF) a disease which can only be treated now by lung transplantation.

1 Dec 2011

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

Ceregene, Inc. reported today that it has completed enrollment in its Phase 2b trial of CERE-120, a gene therapy product expressing the neurturin (NRTN) gene for the treatment of Parkinson's disease.

1 Dec 2011

Yale researchers monitor growth of laboratory-engineered blood vessels after implantation

Using magnetic resonance imaging (MRI) and nanoparticle technology, researchers from Yale have devised a way to monitor the growth of laboratory-engineered blood vessels after they have been implanted in patients. This advance represents an important step toward ensuring that blood vessels, and possibly other tissues engineered from a patient's own biological material, are taking hold and working as expected.

1 Dec 2011

Study presents high-resolution genome-wide p53-binding map for normal human cells

Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. The distinct binding patterns reflect differences in the chromatin (the way DNA is packed with proteins), which may be important for understanding the function of the tumor suppressor protein in cancer cells.

1 Dec 2011

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

The most poisonous substance on Earth - already used medically in small doses to treat certain nerve disorders and facial wrinkles - could be re-engineered for an expanded role in helping millions of people with rheumatoid arthritis, asthma, psoriasis and other diseases, scientists are reporting. Their study appears in ACS' journal Biochemistry.

1 Dec 2011

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Speaking today at the plenary session of the 7th Annual European Antibody Congress in Geneva, Dr. Anat Cohen-Dayag, President and CEO of Compugen Ltd., presented Compugen's Antibody Target Discovery Platform, one of the Company's predictive discovery platforms for novel therapeutic targets.

1 Dec 2011

Fatal prion diseases have a hidden signature

Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature.

1 Dec 2011

Cancer researchers create catalog of possible targets for new treatments

As cancer researchers continue to identify genetic mutations driving different cancer subtypes, they are also creating a catalog of possible targets for new treatments.

1 Dec 2011

Researchers reveal ambivalent role of CXCL12/CXCR4 molecule in myocardial infarction

The chemokine CXCL12 acts as a chemical signal which mobilizes hematopoietic and other types of stem cells to leave the bone marrow and enter the circulation. Secretion of CXCL12 also guides these cells to sites at which the perfusion of tissue is sub-optimal due to localized obstruction of blood flow. These capabilities have made CXCL12 and its cognate receptor CXCR4 interesting candidates for therapies aimed at mitigating the effects of damage to the heart caused by myocardial infarction.

1 Dec 2011

Immune system stimulant used as suppressor to treat chronic graft-versus-host disease

In a study that seems to pivot on a paradox, scientists at Dana-Farber Cancer Institute have used an immune system stimulant as an immune system suppressor to treat a common, often debilitating side effect of donor stem cell transplantation in cancer patients. The effect, in some cases, was profound.

1 Dec 2011

Study finds some people have ability to hallucinate colours at will

Scientists at the University of Hull have found that some people have the ability to hallucinate colours at will - even without the help of hypnosis.

1 Dec 2011

Different brain structures control eye reflexes in the course of life

Structures in the midbrain that developed early in evolution can be responsible for functions in newborns which in adults are taken over by the cerebral cortex. New evidence for this theory has been found in the visual system of monkeys by a team of researchers from the RUB. The scientists studied a reflex that stabilizes the image of a moving scene on the retina to prevent blur, the so-termed optokinetic nystagmus.

1 Dec 2011

New marker may provide more accurate diagnosis of Alzheimer's, FTLD

New research finds a marker used to detect plaque in the brain may help doctors make a more accurate diagnosis between two common types of dementia - Alzheimer's disease and frontotemporal lobar degeneration.

1 Dec 2011

Combination of two techniques promises to improve effectiveness of experimental gene therapies

yeast or phages act not only to tag and target but also to exchange specific genes in DNA A combination of two techniques promises to improve the efficiency and effectiveness of experimental gene therapies, while also reducing potential side effects says a new research report published in the December 2011 issue of the FASEB Journal.

1 Dec 2011

New gene therapy approach safe for patients with muscular dystrophy

Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, the investigators found no side effects from using a "chimeric" virus to deliver replacement genes for an essential muscle protein in patients with muscular dystrophy.

1 Dec 2011

Novel nanocarbon platform shows potential for future bioelectronic implants

Researchers have demonstrated, for the first time, a graphene-based transistor array that is compatible with living biological cells and capable of recording the electrical signals they generate.

1 Dec 2011

Study investigates why American Indians with African ancestry were more fertile

American Indians with African ancestry outdid 'full bloods' in reproductive terms in the early 1900s, despite the odds being against them, according to a new study by Michael Logan from the University of Tennessee in the US. Their increased fertility occurred at a time when things were not going particularly well for full bloods either - in social, economic and health terms.

1 Dec 2011

Medical Science News

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Life as a couch potato can create new fat in fat cells

Body's surveillance for cancer causing damage and response to allergies share common pathway

Insights into causes of Idiopathic Pulmonary Fibrosis

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

Yale researchers monitor growth of laboratory-engineered blood vessels after implantation

Study presents high-resolution genome-wide p53-binding map for normal human cells

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Fatal prion diseases have a hidden signature

Cancer researchers create catalog of possible targets for new treatments

Researchers reveal ambivalent role of CXCL12/CXCR4 molecule in myocardial infarction

Immune system stimulant used as suppressor to treat chronic graft-versus-host disease

Study finds some people have ability to hallucinate colours at will

Different brain structures control eye reflexes in the course of life

New marker may provide more accurate diagnosis of Alzheimer's, FTLD

Combination of two techniques promises to improve effectiveness of experimental gene therapies

New gene therapy approach safe for patients with muscular dystrophy

Novel nanocarbon platform shows potential for future bioelectronic implants

Study investigates why American Indians with African ancestry were more fertile

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