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Study: Bone marrow transplantation may prolong period of cancer-free survival

Bone marrow transplantation with genetically modified cells may prolong the period of cancer-free survival, suggests a study led by Dr. Vivek Rangnekar, associate director of translational research for the Markey Cancer Center at the University of Kentucky.

25 Aug 2011

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Although outbreaks are rare, Ebola virus, the cause of Ebola hemorrhagic fever (EHF), is one of the deadliest known viruses affecting humans. According to the World Health Organization (WHO), approximately 1,850 EHF cases with more than 1,200 deaths have been documented since the virus was identified in 1976.

25 Aug 2011

U.S. DoD announces $2.3M in grants for lupus research

The Lupus Foundation of America (LFA) congratulates Trine Jorgensen, Ph.D., Assistant Staff, Department of Immunology, Cleveland Clinic Foundation and I-Cheng Ho, M.D., Ph.D., Associate Physician, Brigham and Women's Hospital, for being selected to receive research grants totaling $2.3 million from the U.S. Department of Defense's (DoD) Congressionally Directed Peer Reviewed Medical Research Program.

24 Aug 2011

Bacteria tweak their genes and proteins to gain strength

Scientists have discovered that bacteria like E. coli and Salmonella have a sneaky way of making minor alterations to their genes to boost their chances for infection.

24 Aug 2011

IGF1 plays key role in T-cell acute lymphoblastic leukemia

There are numerous specialized growth factors that are responsible for cells of different tissues of our body to divide and differentiate when needed. These hormone-like factors bind to matching receptors on the surface of their target cells and thus give order for the cell to divide. However, a single genetic alteration can be sufficient for the whole system to get out of control.

24 Aug 2011

IARS launches $750,000 anesthesia research grant

The International Anesthesia Research Society (IARS) launched a $750,000 research grant today - the largest single grant offered by the Society in its 90 year history. The Frontiers in Anesthesia Research Award, created in 1995, has traditionally been a $500,000 grant.

24 Aug 2011

First international conference on developmental, translational and clinical pharmacogenomics

The first international conference hosted by the University of South Florida College of Pharmacy will focus on ways to improve health care by customizing drug prescribing and treatment based on an individual's genetic makeup.

24 Aug 2011

Creighton University to study hereditary factors of prostate cancer among African Americans

Creighton University's Hereditary Cancer Center, has received a three-year, $731,278 grant from the U.S. Department of Defense to study the role heredity plays in prostate cancer among African Americans.

24 Aug 2011

Making mistakes while learning has memory benefits

Canadian researchers have found the first evidence that older brains get more benefit than younger brains from learning information the hard way - via trial-and-error learning.

24 Aug 2011

Scientists discover nanoparticles can disrupt intracellular transport pathways

Scientists at the Centre of Cancer Biomedicine at the Norwegian Radium Hospital are the first to show that uptake and accumulation of nanoparticles in cells can disrupt important intracellular transport pathways.

24 Aug 2011

Long-term dynamics of evolution may take around a million years

In research that will help address a long-running debate and apparent contradiction between short- and long-term evolutionary change, scientists have discovered that although evolution is a constant and sometimes rapid process, the changes that hit and stick tend to take a long time.

24 Aug 2011

Largest ever molecular-genetic study of ependymomas of the cerebellum

Ependymomas are the second most frequent type of malignant brain tumor in children. Ependymoma develops from precursor cells of the tissue that lines the hollow cavities of the brain. Therapy results of ependymoma vary immensely: While in some patients tumor growth comes to a standstill after surgery and radiotherapy, in other children the disease rapidly takes a severe course.

24 Aug 2011

Research may help explain why live attenuated influenza vaccine elicits protection

New research from the Trudeau Institute may help to explain why live attenuated influenza vaccine (LAIV), commonly known as FluMist, elicits protection.

24 Aug 2011

DTU, TGen researchers pinpoint source of cholera outbreak in Haiti

Employing technology that reads the entire DNA code, researchers led by the Translational Genomics Research Institute (TGen) and the Technical University of Denmark (DTU) have pinpointed the source of a cholera outbreak in Haiti that killed more than 6,000 people and sickened 300,000.

24 Aug 2011

Researchers discover expression of IL-37 that protects mice from colitis

Inflammatory bowel disease (IBD), which affects more than 1 million patients in North America, results from an uncontrolled immune response triggered by environmental factors, such as bacteria, in people genetically predisposed to the disorder. Ulcerative colitis, or inflammation of the lining of the colon, is one such condition.

24 Aug 2011

New stem cell lines help study genetic, biological underpinnings of bipolar disorder

New stem cell lines developed from the skin of adults living with bipolar disorder are providing researchers at the University of Michigan Health System an unprecedented opportunity to delve into the genetic and biological underpinnings of the devastating mood disorder.

24 Aug 2011

Insight into acrolein-induced acute lung injury

Metabolon, Inc., the leader in metabolomics, biomarker discovery and biochemical analysis, announces the publication of "Integrative Metabolome and Transcriptome Profiling Reveals Discordant Energetic Stress Between Mouse Strains with Differential Sensitivity to Acrolein-Induced Acute Lung Injury" in The Molecular Nutrition and Food Research Journal.

24 Aug 2011

New fertilized cells narrowly avoid degenerating into fatal chaos

Research based at Princeton University has revealed that newly fertilized cells only narrowly avoid degenerating into fatal chaos. At the same time, scientists have discovered that embryos have acquired a mechanism to contain this dangerous instability, a finding that could help biologists unravel other mysteries about the first hours of life.

24 Aug 2011

Scientists show how scaling works in developing fruit fly wings

Weizmann Institute scientists have added a significant piece to the puzzle of scaling - how patterns stay in sync with size as an embryo or organism grows and develops. In a new study appearing in Current Biology, Institute scientists Profs.

24 Aug 2011

Nickel nanoparticles activate cellular pathway that contributes to cancer in lung cells

All the excitement about nanotechnology comes down to this: Structures of materials at the scale of billionths of a meter take on unusual properties. Technologists often focus on the happier among these newfound capabilities, but new research by an interdisciplinary team of scientists at Brown University finds that nanoparticles of nickel activate a cellular pathway that contributes to cancer in human lung cells.

24 Aug 2011