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Luciferase enzyme offers promise for improved monitoring of heparin therapy: New study

The enzyme that makes fireflies glow is lighting up the scientific path toward a long-sought new medical imaging agent to better monitor treatment with heparin, the blood thinner that millions of people take to prevent or treat blood clots, scientists are reporting. Their study appears in the ACS' monthly journal Bioconjugate Chemistry.

10 Feb 2011

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

Cell Medica, a leading UK cellular therapeutics company that develops, manufactures and markets cellular immunotherapy products for the treatment of infectious disease and cancer, announces today that the first patient has been treated in the CMV~ACE/ASPECT trial at University College Hospital London.

10 Feb 2011

Patients with sensorineural hearing loss can benefit from mucosa-derived stem cell transplant

Stem Cell scientists in Australia have found that patients suffering from hearing problems which began during infancy and childhood could benefit from a transplant of stem cells from their nose. The research, published today in STEM CELLS, reveals that mucosa-derived stem cells can help preserve hearing function during the early-onset of sensorineural hearing loss.

10 Feb 2011

Photodynamic therapy could be useful in eradicating tumor-associated lymphatic vessels

Tumor cells have several routes that enable them to move from the primary tumor to distant tissues, a process called metastasis. It is metastasis of the primary tumor that kills most cancer patients. One of the least studied routes of metastasis is the lymphatic system. Many tumors produce factors that promote the formation of new lymphatic vessels (lymphangiogenesis).

10 Feb 2011

Human-worm connection research provides insight into brain development, diseases

"Man is but a worm" was the title of a famous caricature of Darwin's ideas in Victorian England. Now, 120 years later, a molecular analysis of mysterious marine creatures unexpectedly reveals our cousins as worms, indeed.

10 Feb 2011

Physicist creates technology that may enhance pharma industry's early drug discovery capabilities

A Purdue physicist has created technology to detect motion inside three-dimensional tumor spheroids, which may enhance the pharmaceutical industry's early drug discovery capabilities.

10 Feb 2011

Study unveils surprising mechanism that controls brain formation

A study from The Scripps Research Institute has unveiled a surprising mechanism that controls brain formation. The findings have implications for understanding a host of diseases, including some forms of mental retardation, epilepsy, schizophrenia, and autism.

10 Feb 2011

EHSI applauds promising new stem cell treatment for Parkinson's

Emerging Healthcare Solutions, Inc. applauded a new study today revealing a promising new stem cell treatment for Parkinson's.

10 Feb 2011

Scientists generate beating heart cells from skin cells of young patients with severe genetic heart defect

Using skin cells from young patients who have a severe genetic heart defect, Stanford University School of Medicine scientists have generated beating heart cells that carry the same genetic mutation. The newly created human heart cells - cardiomyocytes - allowed the researchers for the first time to examine and characterize the disorder at the cellular level.

10 Feb 2011

Scientists discover KCNH2 gene mutation in patients with long QT syndrome

Researchers from the Hospital Virgen de las Nieves of the University of Granada have identified the most frequent mutations in the gene KCNH2 in patients with long QT syndrome.

10 Feb 2011

L-methylfolate in combination with antidepressant drug helps major depressive disorder patients

Data published in the January issue of Innovations in Clinical Neuroscience, www.psychiatrymmc.com, suggest when L-methylfolate, a medical food available commercially as Deplin®, and by prescription, is used for dietary management of depression in combination with an antidepressant drug at the start of depression therapy, it results in significantly more patients experiencing major improvement and more rapid improvement than antidepressant monotherapy alone.

10 Feb 2011

Mg significantly reduces neonatal brain injury linked with maternal inflammation, infection

In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in San Francisco, researchers will present findings that showed that in rats, the use of magnesium sulfate significantly reduced the neonatal brain injury associated with maternal inflammation or maternal infection.

10 Feb 2011

Liquidia to explore PRINT particle technology with PATH Malaria Vaccine Initiative

Liquidia Technologies today announced a collaboration with the PATH Malaria Vaccine Initiative (MVI) to explore the use of the company's PRINT® particle technology to design next generation malaria vaccines. PRINT technology offers unprecedented control of particle size, shape and chemistry in a highly consistent and scalable manufacturing process, and will be used to deliver a protein in combination with immune stimulating molecules.

10 Feb 2011

Protein cross-linking enzymes in foods can affect physiological characteristics

Protein modification via enzymatic cross-linking is an attractive way for altering food structure so as to create products with increased quality and nutritional value. These modifications are expected to affect not only the structure and physico-chemical properties of proteins but also their physiological characteristics, such as digestibility in the GI-tract and allergenicity.

10 Feb 2011

FDA grants Neuralstem orphan drug designation for treatment of ALS with spinal cord stem cells

Neuralstem, Inc. announced that the U.S. Food and Drug Administration's Office of Orphan Products Development has granted it orphan drug designation for the treatment of Amyotrophic Lateral Sclerosis (ALS) with its human spinal cord derived neural stem cells (NSI-566RSC), currently in a Phase I safety study to evaluate the safety of the product and the surgical route of administration in a wide range of ALS patients.

10 Feb 2011

Seaweed microsponges may help diagnose many diseases quickly, at far lower cost

Microsponges derived from seaweed may help diagnose heart disease, cancers, HIV and other diseases quickly and at far lower cost than current clinical methods. The microsponges are an essential component of Rice University's Programmable Bio-Nano-Chip (PBNC) and the focus of a new paper in the journal Small.

9 Feb 2011

New study: Testosterone administration leads to significant reduction in mind reading

A new study from Utrecht and Cambridge Universities has for the first time found that an administration of testosterone under the tongue in volunteers negatively affects a person's ability to 'mind read', an indication of empathy. The findings are published this week in the journal Proceedings of the National Academy of Sciences.

9 Feb 2011

Single molecule imaging movies of living cell membranes clarify enigma surrounding receptor molecule behaviors

Unprecedented single molecule imaging movies of living cell membranes, taken by a research team based at Kyoto University and the University of New Mexico, have clarified a decades-old enigma surrounding receptor molecule behaviors. The results, appearing in the latest issue of the Journal of Cell Biology, promise to open the door to new possibilities for drug development.

9 Feb 2011

Rapid detection of transiently folded single-molecule structures from 'intrinsically disordered proteins'

A team of scientists from The Scripps Research Institute and the University of California, San Diego (UCSD) have developed a novel technique to observe previously unknown details of how folded structures are formed from an intrinsically disordered protein. The insights could help scientists to better understand the mechanism of plaque formation in neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.

9 Feb 2011

Research findings highlight potential for noninvasive MSC delivery to treat Parkinson disease

Successful intranasal delivery of stem cells to the brains of rats with Parkinson disease yielded significant improvement in motor function and reversed the dopamine deficiency characteristic of the disease.

9 Feb 2011

Medical Science News

Luciferase enzyme offers promise for improved monitoring of heparin therapy: New study

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

Patients with sensorineural hearing loss can benefit from mucosa-derived stem cell transplant

Photodynamic therapy could be useful in eradicating tumor-associated lymphatic vessels

Human-worm connection research provides insight into brain development, diseases

Physicist creates technology that may enhance pharma industry's early drug discovery capabilities

Study unveils surprising mechanism that controls brain formation

EHSI applauds promising new stem cell treatment for Parkinson's

Scientists generate beating heart cells from skin cells of young patients with severe genetic heart defect

Scientists discover KCNH2 gene mutation in patients with long QT syndrome

L-methylfolate in combination with antidepressant drug helps major depressive disorder patients

Mg significantly reduces neonatal brain injury linked with maternal inflammation, infection

Liquidia to explore PRINT particle technology with PATH Malaria Vaccine Initiative

Protein cross-linking enzymes in foods can affect physiological characteristics

FDA grants Neuralstem orphan drug designation for treatment of ALS with spinal cord stem cells

Seaweed microsponges may help diagnose many diseases quickly, at far lower cost

New study: Testosterone administration leads to significant reduction in mind reading

Single molecule imaging movies of living cell membranes clarify enigma surrounding receptor molecule behaviors

Rapid detection of transiently folded single-molecule structures from 'intrinsically disordered proteins'

Research findings highlight potential for noninvasive MSC delivery to treat Parkinson disease

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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