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Case Western Reserve, Athersys enter partnership for scientific study on spinal cord injury

Case Western Reserve University School of Medicine and Athersys, Inc. announced a joint scientific study on spinal cord injury will be published today in the January issue of The Journal of Neuroscience.

19 Jan 2011

Patients with varied patchwork of genetic faults in tumours have worse outcomes

Cancer Research UK scientists have discovered that cervical cancer patients who have a mixture of different genetic faults in their tumour at the start of treatment may be more likely to relapse, according to a study published in the British Journal of Cancer today.

19 Jan 2011

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

A complex sugar may someday become one of the most effective weapons to stop the spread of cholera, a disease that has claimed thousands of lives in Haiti since the devastating earthquake last year.

19 Jan 2011

Study demonstrates role of alpha-synuclein cell-to-cell transfer in Parkinson's disease pathogenesis

The misfolding of abnormal proteins in brain cells is a key element in Parkinson's disease development. A recent study suggests that the sick proteins slowly move between cells, eventually triggering the destruction of the new host cell. The discovery could potentially lead to new therapeutic strategies for neurodegenerative diseases aimed at blocking the spread of protein misfolding throughout the brain.

19 Jan 2011

UNC scientists discover how chaperone enzyme plays a key role in cells' ability to tolerate DNA damage

UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads to cancer and other diseases.

19 Jan 2011

Scientists produce tiny molecular 'binder' that may help develop more efficient drugs

Developing new drugs is a highly costly and time-consuming process. Of 20 candidates, 19 are normally rejected because they don't work or have unwanted side effects. Now a research team led by Professor Lars Baltzer at Uppsala University has produced a tiny molecular "binder" that has the potential to change this landscape radically.

19 Jan 2011

Curcumin and dye brilliant blue G may help block dangerous swelling in TBI

An old Indian spice and a dye whose cousin makes sports drinks blue are pointing scientists toward better treatment of traumatic brain injuries.

19 Jan 2011

Researchers create biyouyanagin compound library

Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for biomedical potential. Already, one of the compounds has shown great promise in inhibiting replication of HIV particles and fighting inflammation.

19 Jan 2011

Convalescent plasma therapy may reduce mortality rate in patients with H1N1 infection: Study

A study published in the February 15 issue of Clinical Infectious Diseases suggests that convalescent plasma may reduce the death rate in patients severely ill with this type of influenza.

19 Jan 2011

New study provides insight into developing therapeutics for airway disease

Researchers from Duke University Medical Center have identified how nanoparticles from diesel exhaust damage lung airway cells, a finding that could lead to new therapies for people susceptible to airway disease.

19 Jan 2011

Meganucleases used to prevent HSV-1 infection

Cellectis, announced today that scientists from Cellectis therapeutics, the French National Center For Medical Research (CNRS) and Institut de la Vision (Paris) have used its proprietary meganucleases to successfully prevent infection of cultured cells by a Herpes Simplex virus (HSV-1).

19 Jan 2011

New patented technique offers unprecedented view of DNA damage

New technology providing the first view of DNA damage throughout the entire human genome developed by Cardiff University scientists could offer a valuable new insight into the development and treatment of conditions like cancer.

19 Jan 2011

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Older adults without dementia and with lower levels in plasma of the biomarkers beta-amyloid 42/40 (protein fragments) had an increased rate of cognitive decline over a period of 9 years, according to a study in the January 19 issue of JAMA. The researchers also found that this relationship was stronger among individuals with less education and lower levels of literacy.

19 Jan 2011

Positive preliminary results from Soligenix's SGX202 in GARS model

Soligenix, Inc., a late-stage biopharmaceutical company, announced today promising preliminary results from a preclinical study of SGX202 in a canine gastrointestinal acute radiation syndrome model.

19 Jan 2011

Cancer cells brought back under normal control

Scientists at The University of Nottingham have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers.

19 Jan 2011

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease, according to a study in the January 19 issue of JAMA.

19 Jan 2011

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Nearly five million Americans live with heart failure, with as many as 700,000 new cases diagnosed each year. In addition to lifestyle factors, scientists have shown that heart failure has a strong heritable component, but identifying the responsible genes has been a major challenge. Now, new research has identified a common genetic risk factor for heart failure in Caucasians that is also linked to kidney function.

19 Jan 2011

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

The Scripps Research Institute has been awarded $3.17 million over four years to develop compounds that will counteract disruptions of the human biological clock - the circadian rhythm that regulates our patterns of activity and rest over a 24-hour daily cycle.

19 Jan 2011

Aastrom secures US patent for autologous cell therapy product

Aastrom Biosciences, a leading developer of expanded autologous cellular therapies for severe, chronic cardiovascular diseases, today announced that it has been granted a U.S. patent which provides composition of matter protection for its investigational expanded autologous cell therapy product.

19 Jan 2011

Antioxidants may cause fertility problems in females

Antioxidants are sold over the counter everywhere. They're added to food, drink and face cream. But according to Prof. Nava Dekel of the Biological Regulation Department, we still don't have a complete understanding of how they act in our bodies. New research by Dekel and her team, recently published in the Proceedings of the National Academy of Sciences USA (PNAS), has revealed a possible unexpected side effect of antioxidants: They might cause fertility problems in females.

19 Jan 2011

Medical Science News

Case Western Reserve, Athersys enter partnership for scientific study on spinal cord injury

Patients with varied patchwork of genetic faults in tumours have worse outcomes

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

Study demonstrates role of alpha-synuclein cell-to-cell transfer in Parkinson's disease pathogenesis

UNC scientists discover how chaperone enzyme plays a key role in cells' ability to tolerate DNA damage

Scientists produce tiny molecular 'binder' that may help develop more efficient drugs

Curcumin and dye brilliant blue G may help block dangerous swelling in TBI

Researchers create biyouyanagin compound library

Convalescent plasma therapy may reduce mortality rate in patients with H1N1 infection: Study

New study provides insight into developing therapeutics for airway disease

Meganucleases used to prevent HSV-1 infection

New patented technique offers unprecedented view of DNA damage

Lower levels in plasma of biomarkers beta-amyloid 42/40 increase rate of cognitive decline

Positive preliminary results from Soligenix's SGX202 in GARS model

Cancer cells brought back under normal control

Molecular imaging procedure may detect beta-amyloid in brain, increase accuracy of AD diagnosis

Common genetic risk factor for heart failure in Caucasians also linked to kidney function

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

Aastrom secures US patent for autologous cell therapy product

Antioxidants may cause fertility problems in females

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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