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Johns Hopkins team reconstitutes single stem cells' family tree

A Johns Hopkins team has discovered in young adult mice that a lone brain stem cell is capable not only of replacing itself and giving rise to specialized neurons and glia - important types of brain cells - but also of taking a wholly unexpected path: generating two new brain stem cells.

2 Jul 2011

Study: Diet soda negatively impacts waistline

You are making a healthier choice when opting for a diet soda instead of a calorie-laden drink, but beware that you don't sabotage your good behavior by indulging in fat-adding foods.

2 Jul 2011

New stem cell bioprinting for uniform, controlled size embryoid body formation

Ever since an ordinary office inkjet printer had its ink cartridges swapped out for a cargo of cells about 10 years ago and sprayed out cell-packed droplets to create living tissue, scientists and engineers have never looked at office equipment in quite the same way. They dream of using a specialized bio-inkjet printer to grow new body parts for organ transplants or tissues for making regenerative medicine repairs to ailing bodies.

2 Jul 2011

U-M researchers a step closer to developing treatments for aging and chronic diseases

As our bodies first form, developing cells are a lot like children put on the school bus with their names and addresses pinned to their shirts. The notes identify one as a future heart cell, another as a liver cell, a third as a neuron. And that's what they each grow up to be. But once those cells reach adulthood, changes to those original marching orders caused by aging, disease and other stressors like smoking can precipitate a kind of identity crisis, researchers at the University of Michigan Health System have found.

2 Jul 2011

MGH researchers discover new plant compounds that block blood vessel growth

Massachusetts General Hospital (MGH) researchers have discovered the first of an entirely new class of antiangiogenesis drugs - agents that interfere with the development of blood vessels.

2 Jul 2011

European joint project to develop novel HCV vaccine based on nanotechnology

HCVAX is a European joint project that reaches out to develop a vaccine against hepatitis C based on nanotechnology. The German Helmholtz Centre for Infection Research in Braunschweig and its department "Vaccinology and Applied Microbiology" is now a part of the transnational consortium with researchers from Germany, France and Switzerland.

2 Jul 2011

Scientists to test whether fish oil can prevent metastatic bowel cancer

Researchers from the University of Leeds will carry out a series of experiments to see whether fish oil can prevent or treat the spread of bowel cancer to the liver.

2 Jul 2011

Transnational research group examines how viruses evade immune system

Understanding the tricks and survival strategies of viruses to effectively combat them: That is the goal of the virtual institute VISTRIE that received its funding commitment today.

2 Jul 2011

Early infection with H. pylori protects against allergy-induced asthma

Infection with the gastric bacterium Helicobacter pylori provides reliable protection against allergy-induced asthma, immunologists from the University of Zurich have demonstrated in an animal model together with allergy specialists from the University Medical Center of the Johannes Gutenberg University Mainz.

2 Jul 2011

T-type calcium channels could provide new approach for treating PD

Parkinson disease (PD) affects 1-2% of the population over the age of 65 years. It results from loss or loss of function of nerve cells in the brain that coordinate movement.

2 Jul 2011

STSI receives NIH grant to conduct heart-based research

Researchers looking to find a root cause for heart attacks and coronary artery disease will soon begin using a novel investigative approach that borders on science fiction as they work toward the holy grail of American medicine: preventing the nation's No. 1 killer.

2 Jul 2011

Genetically engineered pigs may help overcome donor organ shortage

A sizzling genetic discovery by Chinese scientists may one day allow pig tissue to be transplanted successfully into humans. Their research presented in the Journal of Leukocyte Biology (http://www.jleukbio.org) represents a major step forward toward filling the shortage of vital organs for human transplantation.

1 Jul 2011

GWAS identifies 15 gene variants responsible for diversity of white blood cell counts

A trio of large-scale genome-wide association studies, or GWAS, have identified more than 15 gene variants responsible for the diversity of white blood cell counts among whites, African-Americans, and Japanese.

1 Jul 2011

'Genotype positive' individuals susceptible to increased periodontal tissue destruction after dental implants

The health of the surrounding tissue affects the success of a dental implant. Identifying and reducing risk factors is therefore a key step in the implant process. Now a combination of genes has been identified as a possible indicator of greater tissue destruction leading to negative outcomes for implants.

1 Jul 2011

Explicit instruction makes children less likely to engage in spontaneous exploration and discovery

Suppose someone showed you a novel gadget and told you, "Here's how it works," while demonstrating a single function, such as pushing a button. What would you do when they handed it to you?

1 Jul 2011

Novel cerebrospinal fluid proteins found in greater concentrations in Alzheimer's patients

Researchers at the Sahlgrenska Academy, University of Gothenburg, have identified a series of novel proteins in human cerebrospinal fluid. The proteins, which carry specific sugar molecules, are found in greater concentrations in patients with dementia caused by Alzheimer's disease than in patients with dementia caused by other diseases. This gives hope for new forms of treatment in the future.

1 Jul 2011