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Fat linked with DNA chemical changes may help identify risk of cardiovascular disease, diabetes

Fat appears to associate with some distinctive chemical changes in the DNA - a finding that may help explain why obesity can increase the risk for chronic problems such as cardiovascular disease and diabetes, researchers report.

21 Jan 2011

Researchers take systematic approach to catalog factors that control blood cell development

A small pool of stem cells replenishes the human body with about 200 billion new blood cells daily. But the elaborate circuitry that determines if a cell will develop into a T cell, red blood cell, or one of the nine or more other blood cell types remains largely unknown. A research team led by scientists from the Broad Institute and Brigham and Women's Hospital has taken a systematic approach to help decipher this circuitry, compiling a comprehensive catalog of the factors that determine a blood cell's fate.

21 Jan 2011

Repligen enters exclusive license agreement with UCI for use of HDAC3 inhibitors for memory disorders

Repligen Corporation announced today that it has entered into an exclusive license agreement with the University of California, Irvine (UCI) for a patent application covering the use of histone deacetylase 3 (HDAC3) inhibitors for the treatment of disorders involving preservation or extinction of memory including Alzheimer's disease, memory impairment and post traumatic stress disorder.

21 Jan 2011

New study reports success of growing human liver cells on resorbable scaffolds

A new study reports on the success of growing human liver cells on resorbable scaffolds made from material similar to surgical sutures. Researchers suggest that this liver tissue could be used in place of donor organs during liver transplantation or during the bridge period until a suitable donor is available for patients with acute liver failure.

21 Jan 2011

OriGene releases 1,500 mouse monoclonal antibodies

OriGene Technologies, Inc. has recently achieved a significant milestone in its quest for developing an assay for every human protein through the release of 1,500 mouse monoclonal antibodies under the TrueMAB brand. Each TrueMAB antibody is specifically developed with full-length human proteins produced in HEK293T cells and validated for critical research and diagnostic needs requiring improved antibody sensitivity and specificity.

21 Jan 2011

Researchers believe driver mutations promote development, growth of prostate cancer

Prostate cancer is known to occur typically in older men. Yet some patients are younger than 50 years at the time of diagnosis. Scientists assume that these cases might be the key to understanding the biology of this disease. Early prostate cancer might be a subtype which is characterized by a relatively small number of genetic modifications.

21 Jan 2011

New research says EPO hormone can modulate immune response

New research reveals that a hormone best known for stimulating the production of red blood cells can modulate the immune response. The study, published by Cell Press in the January 27th issue of the journal Immunity, finds that erythropoietin has contrasting influences on infectious and inflammatory diseases and may be useful in the design of new therapeutic strategies.

21 Jan 2011

Scientists find ADAR1 enzyme protect against measles virus

Scientists at The Scripps Research Institute have found that a known enzyme in cells protects against measles virus, likely by altering the virus's genetic material, RNA. Cells lacking the enzyme become highly vulnerable to the virus's destructive effects. The enzyme also protects against several other respiratory viruses, including influenza A.

21 Jan 2011

Three ASM scientists to receive NAS award for excellence in microbiology field

Three members of the American Society for Microbiology are among the 13 scientists that will be honored by the National Academy of Sciences with awards recognizing extraordinary scientific achievement in the field of microbiology:

21 Jan 2011

Scientists decipher genetic code for a pancreatic cancer type

Scientists at Johns Hopkins have deciphered the genetic code for a type of pancreatic cancer, called neuroendocrine or islet cell tumors. The work, described online in the Jan. 20 issue of Science Express, shows that patients whose tumors have certain coding "mistakes" live twice as long as those without them.

21 Jan 2011

New research suggests humans use senses to keep track of time

Humans use their senses to help keep track of short intervals of time according to new research, which suggests that our perception of time is not maintained by an internal body clock alone.

21 Jan 2011

Akonni introduces TruTip kit for extraction of human genomic DNA from fresh, frozen whole blood

Akonni Biosystems, a molecular diagnostics company focused on providing rapid and highly scalable solutions for infectious and genetic disease testing, today announced the launch of a TruTip kit for extraction of human genomic DNA from fresh or frozen whole blood.

20 Jan 2011

Researchers discover nitroxoline can reduce human breast, bladder cancer cell growth

Researchers at the Johns Hopkins University School of Medicine have discovered that nitroxoline, an antibiotic commonly used around the world to treat urinary tract infections, can slow or stop the growth of human breast and bladder cancer cells by blocking the formation of new blood vessels.

20 Jan 2011

Genetic expression can be modified with natural substances to prevent chronic illness

Research findings demonstrating how genetic expression can be modified with natural substances to prevent chronic illness was the topic of an address by Jeffrey Bland, Ph.D., FACN, FACB, at the 8th Annual Scripps Center for Integrative Medicine 2011 conference in San Diego, California, January 13 - 16.

20 Jan 2011

Damaged alpha-synuclein proteins can spread in a 'prion-like' manner: Study

The study, published in the Journal of Clinical Investigation, reveals that damaged alpha-synuclein proteins can spread in a 'prion-like' manner, an infection model previously described for diseases such as BSE.

20 Jan 2011

NMDP selects Velos to supply new Product Fulfillment and CDR System

The National Marrow Donor Program announced today that it has selected Velos, a leading California health care software provider, to supply its new Product Fulfillment and Clinical Data Repository System.

20 Jan 2011

ISCT launches commercial development focus group addressing Cell Therapies for Peripheral Vascular Disease

In keeping with its commitment to connect industry, regulatory experts, therapeutic societies and translational centers to advance emerging cellular therapies, ISCT announces its first commercial development focus group addressing Cell Therapies for Peripheral Vascular Disease (PVD).

20 Jan 2011

Scientists discover fundamental mechanism behind toxic protein aggregation in neurodegenerative diseases

Protein aggregation underlies several neurodegenerative diseases such as Alzheimer's, Huntington's chorea or Parkinson's. Scientists at the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, now discovered a fundamental mechanism which explains how toxic protein aggregation occurs and why it leads to a widespread impairment of essential cellular functions.

20 Jan 2011

American Academy of Dermatology's position statement on vitamin D reflects IOM's findings

The American Academy of Dermatology (Academy) has updated its position statement on vitamin D based on the results of a review of the increasing body of scientific literature on this vitamin and its importance for optimal health recently conducted by the National Academy of Sciences Institute of Medicine (IOM).

20 Jan 2011

Brains of migraine sufferers show higher proportion of lesions of brain microvessels

Recent work, in particular the CAMERA study, has used MRI to study the brains of migraine sufferers and has shown that a higher proportion of these patients exhibit lesions of the brain microvessels than the rest of the population.

20 Jan 2011

Medical Science News

Fat linked with DNA chemical changes may help identify risk of cardiovascular disease, diabetes

Researchers take systematic approach to catalog factors that control blood cell development

Repligen enters exclusive license agreement with UCI for use of HDAC3 inhibitors for memory disorders

New study reports success of growing human liver cells on resorbable scaffolds

OriGene releases 1,500 mouse monoclonal antibodies

Researchers believe driver mutations promote development, growth of prostate cancer

New research says EPO hormone can modulate immune response

Scientists find ADAR1 enzyme protect against measles virus

Three ASM scientists to receive NAS award for excellence in microbiology field

Scientists decipher genetic code for a pancreatic cancer type

New research suggests humans use senses to keep track of time

Akonni introduces TruTip kit for extraction of human genomic DNA from fresh, frozen whole blood

Researchers discover nitroxoline can reduce human breast, bladder cancer cell growth

Genetic expression can be modified with natural substances to prevent chronic illness

Damaged alpha-synuclein proteins can spread in a 'prion-like' manner: Study

NMDP selects Velos to supply new Product Fulfillment and CDR System

ISCT launches commercial development focus group addressing Cell Therapies for Peripheral Vascular Disease

Scientists discover fundamental mechanism behind toxic protein aggregation in neurodegenerative diseases

American Academy of Dermatology's position statement on vitamin D reflects IOM's findings

Brains of migraine sufferers show higher proportion of lesions of brain microvessels

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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