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Genes linked to obesity may also cause poor weight loss outcomes after gastric bypass surgery

Researchers at Geisinger Health System are studying how genes may affect a patient's ability to lose weight following bariatric surgery. Highlighted in the journal Obesity, the study found that several genes that promote obesity may also result in inferior weight loss outcomes after gastric bypass surgery.

21 Apr 2011

Scientists discover 'small molecule' substance that blocks cholesterol formation in the brain

A needle-in-the-haystack search through nearly 390,000 chemical compounds had led scientists to a substance that can sneak through the protective barrier surrounding the brain with effects promising for new drugs for Parkinson's and Huntington's disease. They report on the substance, which blocks formation of cholesterol in the brain, in the journal, ACS Chemical Biology.

21 Apr 2011

Early musical study may provide cognitive benefits as we age

Those childhood music lessons could pay off decades later - even for those who no longer play an instrument - by keeping the mind sharper as people age, according to a preliminary study published by the American Psychological Association.

21 Apr 2011

TRIM5 cellular protein helps rhesus monkeys resist HIV

Thanks to a certain protein, rhesus monkeys are resistant to HIV. Known as TRIM5, the protein prevents the HI virus from multiplying once it has entered the cell. Researchers from the universities of Geneva and Zurich have now discovered the protein's mechanism, as they report in Nature. This also opens up new prospects for fighting HIV in humans.

21 Apr 2011

NIH funds Rice University study of new materials for growing replacement heart valves

A team of bioengineers from Rice University is bringing a promising new strategy for growing replacement heart valves closer to reality, thanks to a four-year, $1.2 million grant from the National Institutes of Health. The team hopes to use gel-like materials to generate three-dimensional patterns called scaffolds that can simultaneously mimic the complex structural and physical properties of heart-valve tissues and guide the behavior of tissue-forming cells.

21 Apr 2011

Harvest initiates enrollment in trial of BMAC autologous cell composition to treat Congestive Heart Failure

Harvest Technologies Corp. announced today that the first twelve patients of its sixty patient Heart Failure trial have been enrolled at Medanta-the Medicity in Gurgaon INDIA.

21 Apr 2011

Prenatal exposure to organophosphate pesticides linked to lower IQ in children

In a new study suggesting pesticides may be associated with the health and development of children, researchers at the University of California, Berkeley's School of Public Health have found that prenatal exposure to organophosphate pesticides - widely used on food crops - is related to lower intelligence scores at age 7.

21 Apr 2011

Mindfulness meditation may help make decisions rationally rather than emotionally

If a friend or relative won $100 and then offered you a few dollars, would you accept this windfall? The logical answer would seem to be, sure, why not? "But human decision making does not always appear rational," said Read Montague, professor of physics at Virginia Tech and director of the Human Neuroimaging Laboratory at the Virginia Tech Carilion Research Institute.

21 Apr 2011

ACT seeks European MHRA clearance to initiate hESC derived RPE cell Phase 1/2 study in SMD

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today that it has filed a clinical trial application (CTA) with the European Medicines and Healthcare products Regulatory Agency (MHRA) seeking clearance to initiate its Phase 1/2 clinical trial using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs) to treat patients with Stargardt's Macular Dystrophy (SMD).

21 Apr 2011

Genetically modified mosquitoes tested to prevent spread of malaria: Study

According to the latest study in the journal Nature, researchers from Imperial College London and the University of Washington, Seattle found that after making specific genetic changes to a few mosquitoes and then allowing them to breed could eventually dramatically reduce the spread of the deadly disease malaria.

20 Apr 2011

ARIAD executes three exclusive out-license agreements for ARGENT cell-signaling regulation technology

ARIAD Pharmaceuticals, Inc. today announced execution of three exclusive out-license agreements for separate aspects of its ARGENT™ cell-signaling regulation technology.

20 Apr 2011

Clontech releases iDimerize inducible dimerization systems

Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the release of the iDimerize inducible dimerization systems. Based on the widely used ARGENT™ technology developed by ARIAD Pharmaceuticals, Inc., the iDimerize systems enable precise, real-time control of protein-protein interactions using specific cell-permeable chemical ligands, called dimerizers.

20 Apr 2011

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Two new studies highlight the power of sequencing cancer patients' genomes as a diagnostic tool, helping doctors decide the best course of treatment and researchers identify new cancer susceptibility mutations that can be passed from parent to child.

20 Apr 2011

Blocking abnormal movement of mutated human FUS gene also blocks ALS process

In the first animal model of Amyotrophic Lateral Sclerosis (ALS), developed by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, Dr. Pandey's lab has found in fruit flies that blocking the abnormal movement of a protein made by a mutated gene called FUS also blocks the disease process.

20 Apr 2011

LMP1 viral protein needs TRAF6 cellular protein to promote B cell activation signaling pathways: Study

By identifying a surprising association of two intracellular proteins, University of Iowa researchers have laid the groundwork for the development of new therapies to treat B cell lymphomas and autoimmune disease.

20 Apr 2011

Consumers decide to use mail-in genetic tests based on rational and emotional reasons

Consumers decide whether to use mail-in genetic tests based on both rational and emotional reasons, a finding that adds to a growing body of health-care behavior research on information seeking and avoidance, according to researchers at the University of California, Riverside.

20 Apr 2011

New state of myosin in cardiac muscle with low ATP turnover rate could decrease metabolic load of myocardium

New insight into the physiology of cardiac muscle may lead to the development of therapeutic strategies that exploit an inherent protective state of the heart. The research, published by Cell Press online on April 19th in the Biophysical Journal, discovers a state of cardiac muscle that exhibits a low metabolic rate and may help to regulate energy use and promote efficiency in this hard-working and vital organ.

20 Apr 2011

New biosensor microchip with 'nanosensors' could simultaneously monitor thousands of protein-binding events

Stanford researchers have developed a new biosensor microchip that could significantly speed up the process of drug development. The microchips, packed with highly sensitive "nanosensors," analyze how proteins bind to one another, a critical step for evaluating the effectiveness and possible side effects of a potential medication.

20 Apr 2011

Whole-genome sequencing could soon improve cancer survival rates

Cancer survival rates could improve soon with whole-genome sequencing, according to two studies published in the April 20, 2011, issue of the Journal of the American Medical Association that describe the first clinical applications of the high-tech process in patients with cancer.

20 Apr 2011

Researchers discover new way to force cancer cells to self-destruct

Researchers at The Wistar Institute have found a new way to force cancer cells to self-destruct. Low doses of one anti-cancer drug currently in development, called Gamitrinib, sensitize tumor cells to a second drug, called TRAIL, also currently in clinical development as part of an anticancer regimen.

20 Apr 2011

Medical Science News

Genes linked to obesity may also cause poor weight loss outcomes after gastric bypass surgery

Scientists discover 'small molecule' substance that blocks cholesterol formation in the brain

Early musical study may provide cognitive benefits as we age

TRIM5 cellular protein helps rhesus monkeys resist HIV

NIH funds Rice University study of new materials for growing replacement heart valves

Harvest initiates enrollment in trial of BMAC autologous cell composition to treat Congestive Heart Failure

Prenatal exposure to organophosphate pesticides linked to lower IQ in children

Mindfulness meditation may help make decisions rationally rather than emotionally

ACT seeks European MHRA clearance to initiate hESC derived RPE cell Phase 1/2 study in SMD

Genetically modified mosquitoes tested to prevent spread of malaria: Study

ARIAD executes three exclusive out-license agreements for ARGENT cell-signaling regulation technology

Clontech releases iDimerize inducible dimerization systems

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Blocking abnormal movement of mutated human FUS gene also blocks ALS process

LMP1 viral protein needs TRAF6 cellular protein to promote B cell activation signaling pathways: Study

Consumers decide to use mail-in genetic tests based on rational and emotional reasons

New state of myosin in cardiac muscle with low ATP turnover rate could decrease metabolic load of myocardium

New biosensor microchip with 'nanosensors' could simultaneously monitor thousands of protein-binding events

Whole-genome sequencing could soon improve cancer survival rates

Researchers discover new way to force cancer cells to self-destruct

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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