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Idera presents IMO-3100 data on preclinical model of arthritis at FOCIS 2011

Idera Pharmaceuticals, Inc. announced today the presentation of IMO-3100 mechanism of action data in a preclinical model of arthritis.

24 Jun 2011

CBMi creates iPad app for exploring human genomic information

Navigating the human genome with software that you can view on an iPad® sounds pretty impressive, until perhaps you reflect that nature has already encoded trillions of copies of this in your chromosomes. Then again, printing that data using ink and paper would produce a mind-staggering pile of pages—so viewing it on an iPad® may be impressive after all.

24 Jun 2011

Copenhagen chemist reveals mechanism behind deadly infections

Anthrax, septicemia and meningitis are some of the planet's most deadly infections. In part because doctors lack basic insights to prevent and cure diseases caused by so called Gram-positive bacteria. Now, a chemist from the University of Copenhagen has revealed the mechanism behind these deadly infections.

24 Jun 2011

Potential new approach for treating myelofibrosis

A new study conducted by a team of researchers at Boston University School of Medicine (BUSM) sheds light on a possible new approach to treat the bone marrow disease known as myelofibrosis by inhibiting an enzyme that connects extracellular fibers.

24 Jun 2011

Scientists discover sleep switch in fruit fly's brain

Rather than count sheep, drink warm milk or listen to soothing music, many insomniacs probably wish for a switch they could flick to put themselves to sleep.

24 Jun 2011

Researchers discover new mechanism for origin of Barrett's esophagus

Researchers have discovered a new mechanism for the origin of Barrett's esophagus, an intestine-like growth in the esophagus that is triggered by chronic acid reflux and often progresses to esophageal cancer.

24 Jun 2011

Majority of cancers are due to epigenetic influences

Dr. Ajay Goel, Ph.D., Director of Epigenetics and Cancer Prevention at the Gastrointestinal Research Center at Baylor University Medical Center in Dallas, TX, has announced plans for a series of upcoming studies to continue to unlock the mechanisms by which curcumin prevents cancer via its influence on epigenetic activity.

23 Jun 2011

New proteomics-based approach to analyze bone quality

A new technique developed at Rensselaer Polytechnic Institute allows researchers to collect large amounts of biochemical information from nanoscale bone samples.

23 Jun 2011

Resveratrol may make old age more tolerable, but not prevent it

A University of Florida review of research finds the polyphenol compound known as resveratrol found in red wine, grapes and other fruits may not prevent old age, but it might make it more tolerable.

23 Jun 2011

GUMC neuroscientists: Speech perception must have evolved from animals

Neuroscientists at Georgetown University Medical Center (GUMC) have defined, for the first time, three different processing stages that a human brain needs to identify sounds such as speech - and discovered that they are the same as ones identified in non-human primates.

23 Jun 2011

Fat substituted snack foods may contribute to weight gain

Fat substitutes used in popular snack foods to help people control weight may have the opposite effect, according to Purdue University research.

23 Jun 2011

Insights into type I diabetes

A new signal pathway that renders the insulin-releasing beta cell more sensitive to high levels of blood glucose has been discovered by researchers at the Swedish medical university Karolinska Institutet. A second new study reveals a possible way to delay the disease by inhibiting a lipoprotein.

23 Jun 2011

SNP identification may help predict patients’ susceptibility to postoperative nausea and vomiting

There are several anesthetic complications that may have a hereditary background, including postoperative nausea and vomiting (PONV). Past observations have shown PONV to occur in blood relatives as far back as two to three generations.

23 Jun 2011

New sAPPβ biomarker may identify people at risk of developing Alzheimer's

A new biomarker may help identify which people with mild memory deficits will go on to develop Alzheimer's disease, according to a new study published in the June 22, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Jun 2011

PNAS publishes Roche manuscript on generation of human bispecific IgG antibodies

The Roche manuscript: "Immunoglobulin Domain Crossover as a Generic Approach for the Production of Bispecific IgG Antibodies" has been published in the prestigious Proceedings of the National Academy of Sciences of the USA.

23 Jun 2011

Unraveling molecular dysfunction due to environmental toxin exposure

In a new article published in the journal Molecular Neurodegeneration, researchers at the University of Missouri School of Medicine take some of the first steps toward unraveling the molecular dysfunction that occurs when proteins are exposed to environmental toxins. Their discovery helps further explain recent NIH findings that demonstrate the link between Parkinson's disease and two particular pesticides - rotenone and paraquat.

23 Jun 2011

New surprising details about flow of neurotransmitters between brain neurons

Two studies featuring research from Weill Cornell Medical College have uncovered surprising details about the complex process that leads to the flow of neurotransmitters between brain neurons -- a dance of chemical messages so delicate that missteps often lead to neurological dysfunction.

23 Jun 2011

CPDC, UHN to advance use of medical isotopes for cancer treatment and diagnosis

CanProbe, a unique, not-for-profit joint venture to advance the use of medical isotopes for diagnosing and treating cancer and other serious diseases, was announced today by the Centre for Probe Development and Commercialization (CPDC) and the University Health Network.

23 Jun 2011

HKU releases draft genome sequence of scarlet fever strain

Scarlet fever has revealed unusual high infect rate in Hong Kong this year. So far, 466 children were infected and 2 of them dead. Scarlet fever is caused by Streptococcus pyogenes, a gram-positive pathogen that can be transmitted via skin wound and airborne droplet.

23 Jun 2011

Incivek-combination therapy increases chances of HCV patients achieving viral cure

The drug Incivek, when given in combination with two other medications, can dramatically increase the chances of people chronically infected with untreated genotype 1 hepatitis C virus achieving a viral cure. That's the finding of a study published in the June 23rd issue of the New England Journal of Medicine.

23 Jun 2011