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UW C4C, Pharmigene execute licensing agreement for warfarin personalized medicine technology

The University of Washington Center for Commercialization and Pharmigene, a leader in advancing personalized medicine and reducing severe adverse reactions to drugs through genetic-based diagnostic solutions, today announced the execution of a licensing agreement between the parties.

18 May 2011

Queen's University scientists partner to treat premature baby blindness with stem cells

Scientists from the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast are teaming up to develop a cure to an illness that can lead to blindness in premature babies, thanks to funding from children's charity Action Medical Research.

18 May 2011

Intermittent hypoxia enhances cancer growth in mouse model of obstructive sleep apnea

A new study links the intermittent interruption of breathing that occurs in patients with obstructive sleep apnea to enhanced proliferation of melanoma cancer cells and increased tumor growth in mice, according to researchers in Spain.

18 May 2011

CITN selects Cytheris' CYT107 for initial clinical trials at network institutions

Cytheris SA and the Cancer Immunotherapy Trials Network, a new initiative in immunotherapy funded by the National Cancer Institute with its Central Operations and Statistical Center headquartered at Fred Hutchinson Cancer Research Center, Seattle, Washington, today announced the selection of recombinant human interleukin-7, the investigational multifunctional cytokine under development by Cytheris, as one of the first immunotherapeutic agents proposed for initial clinical trials at network institutions.

18 May 2011

Epstein-Barr virus might cause multiple sclerosis, study confirms

The Epstein-Barr (EVB) virus -belonging to the herpesviruses family, which also includes the herpes simplex virus and the cytomegalovirus- is one of the environmental factors that might cause multiple sclerosis, a condition affecting the central nervous system, which causes are unknown.

18 May 2011

Study: MMN might predict risk of developing schizophrenia

There is a significant need for objective tests that could improve clinical prediction of future psychosis. One strategy has been to determine whether physiologic measures that are abnormal in people diagnosed with schizophrenia might also be useful in estimating the risk for developing this illness. This is the strategy taken by German and Swiss researchers in the current issue of Biological Psychiatry.

18 May 2011

NCNPR and Cancer Institute in Jackson partner for anti-cancer drug research

A new partnership to search for cancer-fighting drugs combines compound-identification and screening expertise at the University of Mississippi's National Center for Natural Products Research with the drug development and clinical-trials capabilities at the University of Mississippi Medical Center Cancer Institute.

18 May 2011

Novel gene associated with heart development and aging process

Researchers at the University of Ottawa Heart Institute (UOHI) have identified a novel gene in the nucleus of muscle and brain cells that affects heart development and the aging process. Their investigation brings the promise of new treatments for an old, failing heart.

18 May 2011

Neurochemical basis for sleep deprivation's effects on memory

From high-school students to surgeons, anyone who has pulled an all-nighter knows there is a price to be paid the next day: trouble focusing, a fuzzy memory and other cognitive impairments. Now, researchers at Penn have found the part of the brain and the neurochemical basis for sleep deprivation's effects on memory.

18 May 2011

Gut bacteria influences brain chemistry and behaviour: Research

For the first time, researchers at McMaster University have conclusive evidence that bacteria residing in the gut influence brain chemistry and behaviour.

18 May 2011

Treatment of chronic low back pain can reverse abnormal brain activity and function

It likely comes as no surprise that low back pain is the most common form of chronic pain among adults. Lesser known is the fact that those withchronic pain also experience cognitive impairments and reduced gray matter in parts of the brain associated with pain processing and the emotional components of pain, like depression and anxiety.

18 May 2011

Impaired ability to handle oxidative stress may contribute to asthma development

An impaired ability to handle oxidative stress that arises from exposure to secondhand smoke and other environmental triggers may contribute to the development of asthma, according to results obtained from the Shanghai Women's Health Asthma and Allergy Study. The results of the study suggest regulating the body's antioxidant defense system may play an important role in asthma prevention.

18 May 2011

Endo and Bioniche present Urocidin Phase III trial preliminary results at 2011 AUA annual meeting

Endo Pharmaceuticals and Bioniche Life Sciences today presented Phase III trial results for the intravesical formulation of Mycobacterial cell wall-DNA complex (MCC), known as Urocidin, during a podium presentation at the 2011 American Urological Association annual meeting in Washington, D.C.

18 May 2011

Leucine deprivation triggers apoptosis in melanoma cells

Whitehead Institute researchers have found that depriving human melanoma cells of the essential amino acid leucine can be lethal to the cells, suggesting a possible strategy for therapeutic intervention.

18 May 2011

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Researchers at the University of Texas Medical Branch at Galveston and the University of California-San Diego School of Medicine have published a study that offers a new understanding of a protein critical to physiological processes involved in major diseases such as diabetes and cancer. This work could help scientists design drugs to battle these disorders.

18 May 2011

USPTO issues notice of allowance to Vermillion's Peripheral Artery Disease biomarker patent

Vermillion, Inc., a molecular diagnostics company, today announced that the United States Patent and Trademark Office has issued a notice of allowance for a patent entitled "Panel of Biomarkers for Peripheral Artery Disease" to the company.

18 May 2011

Cytonet receives FDA orphan drug designation for liver cell infusion to treat urea cycle disorders

International biotechnology firm Cytonet, which is investigating a liver cell infusion of donated human liver cells for the treatment of urea cycle disorders in young children, announced it has been granted orphan drug designation by the U.S. Food and Drug Administration.

18 May 2011

Early exposure to social deprivation and neglect linked to prematurely shortened telomeres in children

Studies in institutionalized Romanian children have found that the length of time spent in conditions of social deprivation and neglect correlates with lower IQ and behavioral problems. A new study, led by researchers at Children's Hospital Boston and Tulane University, shows that early adversity even affects children's chromosomes – prematurely shortening the chromosome tips, known as telomeres, and hastening how quickly their cells "age."

17 May 2011

Cellular 'mechanic' keeps DNA damage in check in cells

CANCER RESEARCH UK scientists have discovered how a protein in immune cells plays an essential role in their development by repairing DNA damage - and if this protein is missing lymphomas can form.

17 May 2011

Researchers lay foundation for future lung cancer detection test

Scientists working with Professor Dr. Joachim L. Schultze have identified over 480 molecules whose concentration in the blood changes when a person develops lung cancer. These molecules are present in the blood cells either in increased or decreased quantities. "In lung cancer patients, typical patterns which can be detected with a measuring program thus emerge", explains Prof. Schultze.

17 May 2011

Medical Science News

UW C4C, Pharmigene execute licensing agreement for warfarin personalized medicine technology

Queen's University scientists partner to treat premature baby blindness with stem cells

Intermittent hypoxia enhances cancer growth in mouse model of obstructive sleep apnea

CITN selects Cytheris' CYT107 for initial clinical trials at network institutions

Epstein-Barr virus might cause multiple sclerosis, study confirms

Study: MMN might predict risk of developing schizophrenia

NCNPR and Cancer Institute in Jackson partner for anti-cancer drug research

Novel gene associated with heart development and aging process

Neurochemical basis for sleep deprivation's effects on memory

Gut bacteria influences brain chemistry and behaviour: Research

Treatment of chronic low back pain can reverse abnormal brain activity and function

Impaired ability to handle oxidative stress may contribute to asthma development

Endo and Bioniche present Urocidin Phase III trial preliminary results at 2011 AUA annual meeting

Leucine deprivation triggers apoptosis in melanoma cells

Study offers new understanding of cell signaling networks tied to diabetes and cancer

USPTO issues notice of allowance to Vermillion's Peripheral Artery Disease biomarker patent

Cytonet receives FDA orphan drug designation for liver cell infusion to treat urea cycle disorders

Early exposure to social deprivation and neglect linked to prematurely shortened telomeres in children

Cellular 'mechanic' keeps DNA damage in check in cells

Researchers lay foundation for future lung cancer detection test

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