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Abcc10 might help counter resistance and extend effectiveness of anticancer drugs

Today's anticancer drugs often work wonders against malignancies, but sometimes tumors become resistant to the effects of such drugs, and treatment fails. Medical researchers would like to find ways of counteracting such resistance, but first they must understand why and how it happens.

17 May 2011

Fluidigm launches 192.24 Dynamic Array integrated fluidic circuit for genome studies

Fluidigm Corporation today introduced its 192.24 Dynamic Array™ IFC, designed to genotype 192 samples against 24 SNP assays in a single run, providing 4,608 data points in just one hour. The 192.24 integrated fluidic circuit (IFC) has immediate applicability in agricultural biotechnology and genome wide association studies.

16 May 2011

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

Mount Sinai School of Medicine and Pacific Biosciences of California, Inc. announced a bi-coastal collaboration to advance clinical research through the Mount Sinai Institute for Genomics and Multiscale Biology to be led by Eric E. Schadt, Ph.D.

16 May 2011

GenturaDx completes external HSV 1&2 alpha studies for IDbox System

Molecular diagnostics company GenturaDx announces the completion of external HSV 1&2 alpha studies for its IDbox instrument and cassette-based tests. Conducted at an external CLIA laboratory, the study analyzed more than 130 samples, including more than 70 clinical specimens.

16 May 2011

Accelerated aging process of cells may play a role in lung inflammation linked with COPD

Changes in the ability of lung cells to divide may play a role in initiating or prolonging lung tissue inflammation, a hallmark of chronic obstructive pulmonary disease (COPD), according to a study conducted by researchers in France.

16 May 2011

International researchers discover new aspect of 'metabolic transformation'

An international research team led by Dr. Tak Mak, Director, The Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital (PMH), has discovered a new aspect of "metabolic transformation", the process whereby tumour cells adapt and survive under conditions that would kill normal cells.

16 May 2011

Computationally designed antiviral proteins may fight against influenza

A research article May 12 in Science demonstrates the use of computational methods to design new antiviral proteins not found in nature, but capable of targeting specific surfaces of flu virus molecules.

16 May 2011

Simple, minimal invasive technique could help detect early-stage lung cancer

A simple, minimally-invasive technique using cells from the interior of the nose could help clinicians detect lung cancer in its earliest - and most treatable - stages, according to a study conducted by researchers in Boston.

16 May 2011

NewGene develops breakthrough test for hereditary breast cancer

A new breakthrough test for hereditary breast cancer developed by UK-based NewGene could see thousands of women being diagnosed with the genetic condition in around half the usual time and at around half the cost of conventional test methods.

16 May 2011

New York Academy of Sciences and Zeltia to host marine drug discovery forum on May 20, 2011

Substances produced by living organisms found in nature-so-called "natural products"-have played a critical role in the development of drugs for life-threatening conditions. The anticancer agent Taxol was sourced from a plant, penicillin from a fungus, and a number of recent breakthroughs have resulted in the development and approval of anticancer drugs derived from marine sources such as coral and sponges.

16 May 2011

Study reveals role of KLF14 regulatory gene in type 2 diabetes

A team of researchers, led by King's College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behaviour of other genes found within fat in the body.

16 May 2011

Pre-existing malaria prevents secondary infection by another Plasmodium strain

A team of researchers have found that pre-existing malaria prevents secondary infection by another Plasmodium strain, the parasite responsible for malaria, by restricting iron availability in the liver of the host.

16 May 2011

Scientists discover single neuron that enables adaptive regulation of sparseness in olfactory codes

The brain is a coding machine: it translates physical inputs from the world into visual, olfactory, auditory, tactile perceptions via the mysterious language of its nerve cells and the networks which they form. Neural codes could in principle take many forms, but in regions forming bottlenecks for information flow or in areas important for memory, sparse codes are highly desirable.

16 May 2011

Study reveals crucial role of histone deacetylases in type 2 diabetes

A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards a new class of drugs for the treatment of metabolic disease.

16 May 2011

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.

16 May 2011

Young scientists receive Intel Foundation top prize for groundbreaking cancer work

Matthew Feddersen and Blake Marggraff from Lafayette, Calif. were awarded the top prize at the Intel International Science and Engineering Fair, a program of Society for Science & the Public. They received $75,000 and the Gordon E. Moore Award, in honor of the Intel co-founder and retired chairman and CEO, for developing a potentially more effective and less expensive cancer treatment that places tin metal near a tumor before radiation therapy.

16 May 2011

Techulon receives U.S. patent protection for Glycofect Discovery and Therapeutic Delivery Platform

Techulon, Inc. announced today that its Glycofect Discovery and Therapeutic Delivery Platform has been awarded United States patent protection. The patented invention provides a new class of non-viral transfection vectors based on synthetic carbohydrate containing polyamides that can be used for both in vivo and in vitro applications.

16 May 2011

Study associates VDR gene variant with onset of chronic obstructive pulmonary disease in men

Researchers have linked a variant in the vitamin D receptor gene (VDR) with the onset of chronic obstructive pulmonary disease (COPD) in Caucasian men. The study population consisted of participants in the Veterans Administration Normative Aging Study, a multidisciplinary study of aging that began in 1963.

16 May 2011

Insight into male infertility

Around one in 20 men is infertile, but despite the best efforts of scientists, in many cases the underlying causes of infertility have remained a mystery.

16 May 2011

AgenoLAB acquires Roche´s RTCA Cardio Instrument

AgenoLAB, the Stuttgart-based service provider, is the first company in Germany to expand its service offering with the latest cell analysis technology from Roche. The company will use the RTCA Cardio Instrument to complement their analytical service portfolio for drug development.

13 May 2011

Medical Science News

Abcc10 might help counter resistance and extend effectiveness of anticancer drugs

Fluidigm launches 192.24 Dynamic Array integrated fluidic circuit for genome studies

Pacific Biosciences, Mount Sinai collaborate to advance genomic research

GenturaDx completes external HSV 1&2 alpha studies for IDbox System

Accelerated aging process of cells may play a role in lung inflammation linked with COPD

International researchers discover new aspect of 'metabolic transformation'

Computationally designed antiviral proteins may fight against influenza

Simple, minimal invasive technique could help detect early-stage lung cancer

NewGene develops breakthrough test for hereditary breast cancer

New York Academy of Sciences and Zeltia to host marine drug discovery forum on May 20, 2011

Study reveals role of KLF14 regulatory gene in type 2 diabetes

Pre-existing malaria prevents secondary infection by another Plasmodium strain

Scientists discover single neuron that enables adaptive regulation of sparseness in olfactory codes

Study reveals crucial role of histone deacetylases in type 2 diabetes

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Young scientists receive Intel Foundation top prize for groundbreaking cancer work

Techulon receives U.S. patent protection for Glycofect Discovery and Therapeutic Delivery Platform

Study associates VDR gene variant with onset of chronic obstructive pulmonary disease in men

Insight into male infertility

AgenoLAB acquires Roche´s RTCA Cardio Instrument

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