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Dopamine vital for rhythmic expression in specific brain regions: Research

Daily sleeping and eating patterns are critical to human well-being and health. Now, a new study from Concordia University has demonstrated how the brain chemical dopamine regulates these cycles by altering the activity of the "clock-protein" PER2. Published in the Journal of Neuroscience, these findings may have implications for individuals with Parkinson's Disease with disrupted 24-hour rhythms of activity and sleep.

21 Oct 2010

Trained service dogs can help children with Autism Syndrome Disorders

Dogs may not only be man's best friend, they may also have a special role in the lives of children with special needs. According to a new Universit- de Montreal study, specifically trained service dogs can help reduce the anxiety and enhance the socialization skills of children with Autism Syndrome Disorders (ASDs).

20 Oct 2010

LANL's researcher to implement first human trial of mosaic HIV vaccine candidate

Los Alamos National Laboratory researcher Bette Korber is part of an international team of investigators working to design and implement the first human trial of a mosaic HIV vaccine candidate. The vaccine represents a novel strategy for fighting the virus that causes AIDS by attempting to address one of the most daunting challenges in HIV vaccine design: the virus's extensive genetic diversity.

20 Oct 2010

RWV bioreactor creates 3-D cell culture models

The cells and tissues in our bodies grow, develop and interact in a highly complex, three-dimensional world. Likewise, the various microbial pathogens that invade our bodies and cause infectious disease interact with this complex 3-D tissue milieu. In the current issue of the journal Nature Reviews Microbiology, researcher Cheryl Nickerson and her team at the Biodesign Institute at Arizona State University highlight an innovative approach for studying cells in 3-D.

20 Oct 2010

New industrial grade of liquid Chloroperoxidase

Bio-Research Products announced today that it will add to its Chloroperoxidase (CPO) offerings a lower cost, industrial grade for application to organic syntheses such as oxidations and halogenations.

20 Oct 2010

A new way of seeing the world

Scientists at The Montreal Neurological Institute and Hospital - The Neuro, McGill University have discovered that our brains have the ability to determine the shape of an object simply by processing specially-coded sounds, without any visual or tactile input. Not only does this new research tell us about the plasticity of the brain and how it perceives the world around us, it also provides important new possibilities for aiding those who are blind or with impaired vision.

20 Oct 2010

First in vivo screening system for complete human nuclear hormone receptor family

The InDanio screening system can be used, for example, to functionally characterize 'orphan' receptors - those for which their natural ligands or specific function are unknown - and thus qualify them as potential targets for drug discovery. The system can also be used to screen compound libraries in order to identify and refine potential new drugs that target NR proteins.

20 Oct 2010

New sandwich wheat bread is an excellent source of antioxidants

In its continuing commitment as a leader in the bread industry, Texas-based Mrs Baird's becomes the first major baking company in its region to fortify its line of sandwich wheat breads, now providing an excellent source of antioxidant vitamins A and E.

20 Oct 2010

Researchers to develop tailor-made pain management strategies for chronic pain

Research presented at this year's American Society of Anesthesiologists Annual Meeting offers new data in the quest to develop tailor-made pain management strategies based upon a patient's genetic predisposition and other important factors.

20 Oct 2010

MU researchers examine Aspergillus fumigatus to find cure for fungus, parasite

If finding the cure for a fungus and parasite that affects millions of people were the subject of a detective show, University of Missouri Chemistry Professor John Tanner would be the forensic expert in the lab, using high-tech equipment to make a model that could eventually solve the crime.

20 Oct 2010

Carbon dioxide plays a role in gene regulation: Research

UCD Conway researchers have found that carbon dioxide (CO2) is not only involved in climate change and a waste product of respiration in cells but also plays an active role in regulating the genes involved in inflammation and innate immunity. Their research findings were highlighted recently in the The Journal of Immunology.

20 Oct 2010

EPO grants new patent to Silence Therapeutics’ RNAi structural modification technology

Silence Therapeutics plc announces that the European Patent Office (EPO) has granted a new patent that provides broad protection on novel aspects of the RNAi structural modification technology known as the Zamore Design Rules.

20 Oct 2010

New approaches to explore causes of autoimmunity and immune deficiency diseases

A newly identified regulatory process affecting the biology of immune system T cells should give scientists new approaches to explore the causes of autoimmunity and immune deficiency diseases.

20 Oct 2010

Study reveals how cells crank up cancer activators

A new technique that searches blood for the tiniest remnants of broken down proteins has revealed new information about how cells crank up cancer activators called proteases. The results improve researchers' understanding of the mechanics of breast cancer and point to where to look for possible indicators of early disease.

20 Oct 2010

Turmeric component enhances chemotherapy's suppression of head and neck cancer

Curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy's suppression of head and neck cancer cell growth, researchers with UCLA's Jonsson Cancer Center have found.

20 Oct 2010

Study finds different activity patterns of genes in brain of individuals with different genetic backgrounds

Researchers at the Allen Institute for Brain Science have found that the same genes have different activity patterns in the brain in individuals with different genetic backgrounds. These findings may help to explain individual differences in the effectiveness and side-effect profiles of therapeutic drugs and thus have implications for personalized medicine. The study is available in this week's online early edition of the Proceedings of the National Academy of Sciences (www.pnas.org).

20 Oct 2010

UH researchers to explore role of Vitamin D in esophageal cancer prevention

In a first-of-its-kind clinical trial, physicians at University Hospitals (UH) Case Medical Center who are Case Western Reserve University School of Medicine researchers are exploring the role of Vitamin D in preventing esophageal cancer.

20 Oct 2010

Experts at Ninth International Symposium discuss health effects and safety of S-equol

The latest research into the health effects and safety of a soy-based compound called S-equol was described in talks and presentations by experts at a special session on Tuesday, Oct. 19 during the Ninth International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment, held Oct. 16 to 19 in Washington, D.C.

20 Oct 2010

Mirna announces USPTO allows claims to therapeutic application of let-7 miRNA

Mirna Therapeutics, Inc. announced today that the USPTO has allowed claims related to the therapeutic application of let-7 in the regulation of oncogenes. The claims derive from a patent application that was submitted by Yale University and exclusively licensed to Mirna related to the pioneering work of Dr. Frank Slack, Professor of Molecular, Cellular & Developmental Biology at Yale University in New Haven, CT.

20 Oct 2010

Research offers important insight into symptoms of Parkinson's disease

An international collaboration led by academics at the University of Sheffield, has shed new light into Parkinson's disease, which could help with the development of cures or treatments in the future.

20 Oct 2010