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SHIP and PTEN enzymes act cooperatively to suppress B cell lymphoma: Study

Lymphoma is a cancer of the immune system. White blood cells divide again and again, spreading abnormally throughout the body. Lymphomas can arise from two types of white blood cells, T cells or B cells, which divide uncontrollably when the molecular mechanisms that keep them in check go awry.

20 Oct 2010

New disease pathways involving more than one cell type lead to Type 1 Gaucher disease: Study

Researchers at Yale School of Medicine have found that new disease pathways involving more than one cell type leads to Type 1 Gaucher disease, a rare genetic disorder in which fatty substances called glycosphingolipids accumulate in cells, resulting in liver/spleen enlargement, osteoporosis, bone pain, and increased risk of cancer and Parkinson's disease.

20 Oct 2010

Study reveals sex hormones can influence structure and function of heart's right ventricle

In the largest human study to date on the topic, researchers have uncovered evidence of the possible influence of human sex hormones on the structure and function of the right ventricle (RV) of the heart.

20 Oct 2010

Japanese study finds proton beam therapy safe and effective for Stage I inoperable NSCLC

Proton beam therapy is safe and effective and may be superior to other conventional treatments for Stage I inoperable non-small cell lung cancer (NSCLC) patients, according to a study in the October issue of the International Journal of Radiation Oncology•Biology•Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

20 Oct 2010

USPTO grants two additional patents to Ryogen

Ryogen LLC, a genomic research and development company focusing on genes with applications in biomedical research, has been awarded two additional patents on human genes.

20 Oct 2010

Gene that protects against alcoholism discovered

Researchers from the University of North Carolina at Chapel Hill School of Medicine have discovered a gene variant that may protect against alcoholism.

20 Oct 2010

Study shows impaired insulin sensitivity may serve as mediator between obesity and cognitive decline

Because of impairments in their insulin sensitivity, obese individuals demonstrate different brain responses than their normal-weight peers while completing a challenging cognitive task, according to new research by psychologists at The University of Texas at Austin.

20 Oct 2010

Research paves way to understand the mechanism of leptin therapy to improve type 1 diabetes

New findings by UT Southwestern Medical Center researchers suggest a novel role for the brain in mediating beneficial actions of the hormone leptin in type 1 diabetes.

20 Oct 2010

Researchers to study effectiveness of gamma-tocotrienol on prostate cancer cells

Survival rates of the world's most common cancer might soon be increased with a new vitamin E treatment which could significantly reduce tumour regrowth. Queensland University of Technology (QUT) prostate cancer researchers are leading the fight against a disease which kills 3000 Australian men a year.

20 Oct 2010

Study finds adipose dysfunction linked to steatosis, necroinflammation in G1 CHC patients

Researchers at the University of Palermo in Italy provide the evidence that a higher visceral adiposity index score-a new index of adipose dysfunction-has a direct correlation with viral load and is independently associated with both steatosis and necroinflammatory activity in patients with genotype 1 chronic hepatitis C (G1 CHC).

20 Oct 2010

Autistic children with poor diet face risk of vision loss due to vitamin B12 deficiency

Autistic children with severely limited diets may be at risk for vision loss due to vitamin B12 deficiency, according to new research from The Children's Hospital of Philadelphia. Doctors should consider this deficiency when evaluating and treating children with autism and vision loss, the authors said.

20 Oct 2010

Protein hormone inhibits leptin-induced migration of liver cancer cells

A research team from Emory University School of Medicine investigated the role between adiponectin and leptin in obesity-related carcinogenesis. Their findings, published in the November issue of Hepatology, suggest that the protein hormone adiponectin has potential for inhibiting the oncogenic actions of leptin, namely in hepatocellular carcinoma (HCC), and could offer a promising therapy for the disease.

19 Oct 2010

BioMarin announces BMN-111 program for treatment of achondroplasia

BioMarin Pharmaceutical Inc. today announced its program for BMN-111, a peptide therapeutic for the treatment of achondroplasia. BioMarin plans to file an IND in the fourth quarter of 2011 and to initiate a Phase 1 clinical trial by the first quarter of 2012.

19 Oct 2010

Scientists probe functional connectivity among neurons in auditory cortex gives rise to map of acoustic space

Just as we visually map a room by spatially identifying the objects in it, we map our aural world based on the frequencies of sounds. The neurons within the brain's "hearing center"-the auditory cortex-are organized into modules that each respond to sounds within a specific frequency band. But how responses actually emanate from this complex network of neurons is still a mystery.

19 Oct 2010

Pharmacy graduate awarded national recognition for pioneering research in genetics

A young pharmacy graduate has been awarded national recognition for her pioneering research in the field of genetics which has the potential to treat diseases such as cancer and Parkinson's.

19 Oct 2010

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to cortex

A team co-led by neuroscientists at Cold Spring Harbor Laboratory (CSHL) has shed light -- literally -- on circuitry underlying the olfactory system in mammals, giving us a new view of how that system may pull off some of its most amazing feats.

19 Oct 2010

Cytheris initiates ORVACS Phase II clinical trial to study HIV infection

Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced the initiation of Phase II clinical trial of the company's investigative immunomodulatory agent, CYT107 (rhIL-7), in combination with two potent antiretroviral drugs represented by the integrase inhibitor raltegravir (ISENTRESS- Merck & Co.) and the CCR5 inhibitor, maraviroc (SELZENTRY- ViiV Healthcare).

19 Oct 2010

An overview on American College of Gastroenterology's Annual Scientific meeting

The association between obesity and gastrointestinal-related cancers and coronary artery disease; the link between an overweight or obese body mass index and the severity of Crohn's disease; and whether inflammatory bowel disease is an independent risk factor for coronary artery disease, were among the highlights of new research that was presented this week at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio.

19 Oct 2010

Study evaluates collaborative nature of translational medicine

Taking a cue from the world of business-performance experts and baseball talent scouts, Penn Medicine translational medicine researchers are among the first to find a way to measure the productivity of collaborations in a young, emerging institute. They published their findings the most recent issue of Science Translational Medicine.

19 Oct 2010

Study finds process of going in and out of anesthesia as distinct neurobiological processes

A study presented at this year's Annual Meeting of the American Society of Anesthesiologists strengthens emerging evidence that the act of going under anesthesia and coming out of anesthesia are distinct neurobiological processes. It also found that the parietal region of the brain may play a critical role in how anesthesia suppresses consciousness.

19 Oct 2010

Medical Science News

SHIP and PTEN enzymes act cooperatively to suppress B cell lymphoma: Study

New disease pathways involving more than one cell type lead to Type 1 Gaucher disease: Study

Study reveals sex hormones can influence structure and function of heart's right ventricle

Japanese study finds proton beam therapy safe and effective for Stage I inoperable NSCLC

USPTO grants two additional patents to Ryogen

Gene that protects against alcoholism discovered

Study shows impaired insulin sensitivity may serve as mediator between obesity and cognitive decline

Research paves way to understand the mechanism of leptin therapy to improve type 1 diabetes

Researchers to study effectiveness of gamma-tocotrienol on prostate cancer cells

Study finds adipose dysfunction linked to steatosis, necroinflammation in G1 CHC patients

Autistic children with poor diet face risk of vision loss due to vitamin B12 deficiency

Protein hormone inhibits leptin-induced migration of liver cancer cells

BioMarin announces BMN-111 program for treatment of achondroplasia

Scientists probe functional connectivity among neurons in auditory cortex gives rise to map of acoustic space

Pharmacy graduate awarded national recognition for pioneering research in genetics

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to cortex

Cytheris initiates ORVACS Phase II clinical trial to study HIV infection

An overview on American College of Gastroenterology's Annual Scientific meeting

Study evaluates collaborative nature of translational medicine

Study finds process of going in and out of anesthesia as distinct neurobiological processes

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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