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Study confirms Azilect as a selective MAO-B inhibitor

Teva Neuroscience Inc. today announced the publication of a study demonstrating the selectivity of Azilect® (rasagiline tablets) for inhibition of MAO-B (monoamine oxidase-B) at the maximum approved dose of 1 mg/day. The data was published in the Journal of Clinical Pharmacology OnlineFirst on May 5, 2010.

4 Jun 2010

Anti-seizure drug can be used to treat AT deficiency: Pitt researchers

The liver scarring of α1-antitrypsin deficiency, the most common genetic cause for which children undergo liver transplantation, might be reversed or prevented with a medication that has long been used to treat seizures, according to findings from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine that will published in Science and are available online today through the Science Express website.

4 Jun 2010

GPI executive director announces keynote speakers, panel topics for 2010 World Stem Cell Summit

Bernard Siegel, executive director of the Genetics Policy Institute and co-chair of the 2010 World Stem Cell Summit, announced the selection of keynote speakers for the World Stem Cell Summit, which is taking place at the Detroit Marriott Renaissance Center in Detroit, Michigan, October 4-6.

4 Jun 2010

Key regulator of fat cell differentiation identified

New research led by UCD Conway Fellow, Professor Johan Ericsson has identified a key regulator of fat cell differentiation that may be a novel target for obesity drugs. The results of the research are published in the current edition of the scientific journal, Proceedings of the National Academy of Sciences (PNAS).

4 Jun 2010

Researchers find a way to isolate pancreatic islet cells from brain dead donors using DI

A team of researchers from several collaborating Baylor University research centers and from Japan's Okayama Graduate School of Medicine have found a way to more consistently isolate pancreatic islet cells from brain dead donors using ductal injection, a process that immediately cools donor islet cells at the injection site.

4 Jun 2010

Researchers identify region of DNA that may contain gene linked to progression, spread of bowel cancer

Scientists have identified a region of DNA that appears to be involved in the development of pre-cancerous bowel growths (polyps) and that may contain a gene involved in the progression of bowel cancer.

4 Jun 2010

Research finding suggests possibilities for future treatment of anxiety disorders

Researchers at the University of Puerto Rico, School of Medicine have found a way to pharmacologically induce a memory of safety in the brain of rats. As reported in the June, 4 2010 issue of Science, administering brain-derived neurotrophic factor into the prefrontal cortex prevented rats from expressing fear to a tone that had been previously paired with a shock.

4 Jun 2010

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

A detailed analysis of the epigenetics - factors controlling when and in what tissues genes are expressed - of Wilms tumor reveals striking similarities to stem cells normally found in fetal kidneys. These findings by Massachusetts General Hospital Cancer Center researchers have revealed new cellular pathways that are critical for Wilms tumor development and may also apply to other pediatric cancers.

4 Jun 2010

CHOC Children's receives royalty-free research license to certain StemCells' patents

StemCells, Inc. and the Children's Hospital of Orange County ("CHOC Children's") announced today that they have entered into an agreement that provides CHOC Children's with a royalty-free research license to certain of StemCells' patents. This license authorizes CHOC Children's to proliferate, maintain and use human neural stem cells for non-commercial purposes.

4 Jun 2010

SERCA2a gene therapy proves effective in people with advanced heart failure: Researchers

Researchers at Mount Sinai School of Medicine have developed a new gene therapy that is safe and effective in reversing advanced heart failure. SERCA2a (produced as MYDICAR-) is a gene therapy designed to stimulate production of an enzyme that enables the failing heart to pump more effectively.

4 Jun 2010

New pricing of $19,500 set for Illumina's individual genome sequencing service

Illumina, Inc. today announced a new price of $19,500 for its individual genome sequencing service. In addition, the company announced a price of $14,500 per genome for groups of five or more participants using the same physician. Individuals with serious medical conditions for whom whole-genome sequencing could provide potential direct clinical value will be eligible for special pricing of $9,500 per genome.

From Illumina, Inc. 4 Jun 2010

New synthetic Petri dish harvests human embryonic stem cells

A new synthetic Petri dish coating could overcome a major challenge to the advancement of human embryonic stem cell research, say University of Michigan researchers.

3 Jun 2010

New approach to treat RA can change lives of millions of patients: Research

Portuguese scientists have just published a revolutionary new approach to treat rheumatoid arthritis (RA) which, if translated to humans, can change the way we treat autoimmunity (and so diseases like RA but also diabetes and MS) and, with it, the lives of millions of patients.

3 Jun 2010

X+ allele of APOB gene is important risk factor of gallstone formation after gastrectomy: Research

The cause of higher incidence of gallstone after radical gastrectomy still remains unknown. Almost all previous studies have attributed gallstone formation to gallbladder motility disorder after gastrectomy, But this theory cannot completely explain it. Is there any other risk factor of gallstone formation after gastrectomy?

3 Jun 2010

U-M researchers one step closer to discovering why certain diseases affect specific organs

Why do some diseases affect only specific organs, leaving others invulnerable? Researchers from the University of Michigan have found neural tissue contains imbalanced levels of proteins, which may explain the brain's susceptibility to a debilitating childhood movement disorder.

3 Jun 2010

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Life Technologies Corporation and the German Cancer Research Center (Deutsches Krebsforschungszentrum or DKFZ) today announced their collaboration to create the National High-Throughput Sequencing Center. This exclusive partnership will create the largest sequencing facility in Germany and the first national sequencing center in Europe dedicated to systems biology.

3 Jun 2010

Researchers discover relationship between DNA methylation and positioning of nucleosomes

A previously unknown pattern in DNA methylation - an event that affects cell function by altering gene expression - has been uncovered for the first time by stem cell researchers at UCLA, a finding that could have implications in preventing some cancers and correcting defects in human stem cell lines.

3 Jun 2010

Researchers describe chain of molecular events that increase one's risk of skin cancer

As people head to the beach this summer, very few if any, really know how likely they are to develop skin cancer from their outdoor fun. That's about to change, thanks to a new discovery by an international team of scientists that makes it possible for doctors to access people's personal risk for skin cancer.

3 Jun 2010

Canadian researchers: Probiotic found in breast milk reduces painful cramping in gut

Here's another reason to breast feed your baby: Canadian researchers have discovered how a probiotic found in breast milk reduces or eliminates painful cramping in the gut. In a new research report published online in the FASEB Journal, these scientists use mice to show that a specific strain of Lactobacillus reuteri decreases the force of muscle contractions in the gut within minutes of exposure.

3 Jun 2010

Discovery provides new therapeutic target to prevent brain function loss

Researchers at Mount Sinai School of Medicine have found that certain types of specializations on nerve cells called "spines" are depleted as a person ages, causing cognitive decline in the part of the brain that mediates the highest levels of learning. These spines receive an important class of synapses that are involved with the process of learning.

3 Jun 2010

Medical Science News

Study confirms Azilect as a selective MAO-B inhibitor

Anti-seizure drug can be used to treat AT deficiency: Pitt researchers

GPI executive director announces keynote speakers, panel topics for 2010 World Stem Cell Summit

Key regulator of fat cell differentiation identified

Researchers find a way to isolate pancreatic islet cells from brain dead donors using DI

Researchers identify region of DNA that may contain gene linked to progression, spread of bowel cancer

Research finding suggests possibilities for future treatment of anxiety disorders

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

CHOC Children's receives royalty-free research license to certain StemCells' patents

SERCA2a gene therapy proves effective in people with advanced heart failure: Researchers

New pricing of $19,500 set for Illumina's individual genome sequencing service

New synthetic Petri dish harvests human embryonic stem cells

New approach to treat RA can change lives of millions of patients: Research

X+ allele of APOB gene is important risk factor of gallstone formation after gastrectomy: Research

U-M researchers one step closer to discovering why certain diseases affect specific organs

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Researchers discover relationship between DNA methylation and positioning of nucleosomes

Researchers describe chain of molecular events that increase one's risk of skin cancer

Canadian researchers: Probiotic found in breast milk reduces painful cramping in gut

Discovery provides new therapeutic target to prevent brain function loss

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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