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Liquid crystal droplets could replace horseshoe crab blood in common endotoxin test

The Food and Drug Administration requires every drug they certify to be tested for certain poisons that damage patient health. The current gold standard for this is the limulus amoebocyte lysate assay that involves using the blood of horseshoe crabs, which strangely enough is blue, to test for endotoxin, a substance commonly associated with many symptoms caused by bacterial infections.

24 May 2011

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according to an article published today in the journal Experimental Nephrology. Diabetic nephropathy is the foremost cause of kidney failure.

24 May 2011

Caffeine reduces muscle activity in Fallopian tubes

Caffeine reduces muscle activity in the Fallopian tubes that carry eggs from a woman's ovaries to her womb. "Our experiments were conducted in mice, but this finding goes a long way towards explaining why drinking caffeinated drinks can reduce a woman's chance of becoming pregnant," says Professor Sean Ward from the University of Nevada School of Medicine, Reno, USA. Ward's study is published today in the British Journal of Pharmacology

24 May 2011

Novel hepatitis C-like virus discovered in dogs

In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease.

24 May 2011

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders, suggests a study led by Vanderbilt University Medical Center researcher Fang Yan, M.D., Ph.D.

24 May 2011

Variant of obesity gene may increase breast cancer risk

New research aimed to better identify the genetic factors that lead to breast cancer has uncovered a link between the fat mass and obesity associated gene and a higher incidence of breast cancer.

24 May 2011

Inotuzumab ozogamicin achieves over 50% response rate against acute lymphoblastic leukemia

An antibody packaged with a potent chemotherapy drug to selectively destroy acute lymphoblastic leukemia (ALL) cells eradicated or greatly reduced the disease for 61 percent of 46 patients in a phase II study. It will be presented at the 47th annual meeting of the American Society of Clinical Oncology in Chicago June 3-7.

24 May 2011

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment of human sarcomas. The research is published in the current issue of the journal Cancer Cell.

24 May 2011

Scientists discover genetic regions that affect severity of cystic fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis, the most common lethal genetic disease affecting children in North America.

24 May 2011

'Survival protein' protects brain against effects of stroke

Johns Hopkins scientists say that a newly discovered "survival protein" protects the brain against the effects of stroke in rodent brain tissue by interfering with a particular kind of cell death that's also implicated in complications from diabetes and heart attack.

24 May 2011

African-Americans with multiple sclerosis have lower vitamin D levels

African-Americans who have multiple sclerosis have lower vitamin D levels than African-Americans who don't have the disease, according to a study published in the May 24, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

24 May 2011

MO BIO Laboratories introduces PowerWater Sterivex DNA Isolation Kit

MO BIO Laboratories, Inc., the leader in soil, water and microbial nucleic acid purification, announces the launch of an innovative new product, the PowerWater Sterivex DNA Isolation Kit.

23 May 2011

'Turkey tail' mushroom effectively suppresses prostate tumour development

A mushroom used in Asia for its medicinal benefits has been found to be 100 per cent effective in suppressing prostate tumour development in mice during early trials, new Queensland University of Technology (QUT) research shows.

23 May 2011

Low doses of natural Hi-maize resistant starch could improve insulin sensitivity in men at risk for prediabetes

Low doses of natural Hi-maize resistant starch could improve insulin sensitivity in men at risk for prediabetes, according to a study underwritten by National Starch LLC, a business unit of Corn Products International. The American Diabetes Association defines prediabetes as a non-disease state where blood sugar (glucose) levels are higher than normal, but not yet high enough to be diagnosed as diabetes.

23 May 2011

Vertex receives FDA approval for INCIVEK to treat hepatitis C

Vertex Pharmaceuticals Incorporated announced that the U.S. Food and Drug Administration (FDA) has approved INCIVEK™ (telaprevir) tablets for a broad group of people with genotype 1 chronic hepatitis C with compensated liver disease (some level of damage to the liver but the liver still functions), including cirrhosis (scarring of the liver).

23 May 2011

Nano-complex pre-meal dietary supplement can reduce fat and sugar absorption in the body

A little bitter with a little sweet, in the form of a nano-complex dietary supplement taken before meals, can result in a substantial reduction of fat and sugar absorption in the body, Hebrew University of Jerusalem and Harvard University researchers have found.

23 May 2011

New technique can detect minute traces of tumoral DNA in biological fluids

It will perhaps be possible, in the near future, to detect cancer by a simple blood or urine test. In fact, biologists from CNRS, Inserm, Paris Descartes and Strasbourg universities have developed a technique capable of detecting minute traces of tumoral DNA present in the biological fluids of patients suffering from cancer.

23 May 2011

Cognitive behavioural treatment can serve as effective alternative to GA for patients with dental phobia

A study published in the current issue of Psychotherapy and Psychosomatics examines a relatively frequent problem. Individuals who fear the dentist should often recur to some kinds of general anaesthesia to have their dental work done. But alternatives are now available.

23 May 2011

Lund University researcher discovers new sepsis biomarker in blood

Sepsis is the name of an infection that causes a series of reactions in the body, which in the worst case can prove fatal. The problem for both patients and doctors is that the early symptoms are difficult to distinguish from less dangerous infections such as a severe flu or winter vomiting disease.

23 May 2011

Novel compound could become an effective alternative to common narcotic analgesics

Scientists from the Florida campus of The Scripps Research Institute have for the first time accomplished a laboratory synthesis of a rare natural product isolated from the bark of a plant widely employed in traditional medicine.

23 May 2011

Medical Science News

Liquid crystal droplets could replace horseshoe crab blood in common endotoxin test

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

Caffeine reduces muscle activity in Fallopian tubes

Novel hepatitis C-like virus discovered in dogs

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

Variant of obesity gene may increase breast cancer risk

Inotuzumab ozogamicin achieves over 50% response rate against acute lymphoblastic leukemia

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

Scientists discover genetic regions that affect severity of cystic fibrosis

'Survival protein' protects brain against effects of stroke

African-Americans with multiple sclerosis have lower vitamin D levels

MO BIO Laboratories introduces PowerWater Sterivex DNA Isolation Kit

'Turkey tail' mushroom effectively suppresses prostate tumour development

Low doses of natural Hi-maize resistant starch could improve insulin sensitivity in men at risk for prediabetes

Vertex receives FDA approval for INCIVEK to treat hepatitis C

Nano-complex pre-meal dietary supplement can reduce fat and sugar absorption in the body

New technique can detect minute traces of tumoral DNA in biological fluids

Cognitive behavioural treatment can serve as effective alternative to GA for patients with dental phobia

Lund University researcher discovers new sepsis biomarker in blood

Novel compound could become an effective alternative to common narcotic analgesics

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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