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Study on flavors of laughter

Most scientific research on laughter is based on recordings of people pretending to laugh. But for Michael Owren of Georgia State University in Atlanta, this false laughter -- the sound of a canned sit-com laugh track -- is a pale imitation of the real thing. He studies the full vocabulary of chortles, giggles, guffaws we all use in everyday situations.

12 Nov 2010

Research unveils epigenetic function of MECP2 gene tht cause neuropsychiatric disorders

The laboratory of Huda Zoghbi, where the discovery that mutations in the gene MECP2 cause the severe childhood neurological disorder Rett Syndrome was made, has taken yet another step toward unraveling the complex epigenetic functions of this gene, implicated also in cases of autism, bipolar disease and childhood onset schizophrenia. The November 11 issue of Nature reports that removing MECP2 from a small group of neurons that typically make the inhibitory neurotransmitter, GABA, recapitulates many symptoms of Rett as well as numerous neuropsychiatric disorders.

12 Nov 2010

Discovery on immune system paves way to new vaccine against pneumococcal disease

A new breakthrough in the fight against pneumonia, meningitis and septicaemia has been announced today by scientists in Leicester and Dublin. The discovery will lead to a dramatic shift in our understanding of how the body's immune system responds to infection caused by Streptococcus pneumoniae and pave the way for more effective vaccines.

12 Nov 2010

PenCLAHRC provides funding to support C. difficile research

The Peninsula Collaboration for Leadership in Applied Health Research and Care (PenCLAHRC) has provided funding to support joint research between the University of Exeter and the Royal Devon & Exeter NHS Foundation Trust to investigate why some cases of Clostridium difficile infection (CDI) are more difficult to treat than others and also why some cases result in more incidences of relapses.

12 Nov 2010

GPI launches new advocacy coalition to advance embryonic stem cell research in U.S.

The Genetics Policy Institute (GPI) today announced the launch of a new advocacy coalition of 30 organizations to foster public awareness and advance the cause of embryonic stem cell research in the United States.

12 Nov 2010

Study finds arsenic improves survival rate in APL patients

Arsenic, a toxic compound with a reputation as a good tool for committing homicide, has a significant positive effect on the survival of patients with acute promyelocytic leukemia (APL), when administered after standard initial treatment, according to a new, multi-center study led by a researcher at Wake Forest University Baptist Medical Center.

12 Nov 2010

Stanford University scientist receives HFSP Nakasone Award for neuronal network study

The first HFSP Nakasone Award has been conferred upon Karl Deisseroth of Stanford University for his pioneering work on the development of optogenetic methods for studying the function of neuronal networks underlying behavior.

12 Nov 2010

StemCyte receives two cash grants under QTDP program for biomedical research

StemCyte, Inc., one of the world's preeminent umbilical cord blood (UCB) banks and biotherapy companies, is proud to announce that the Company has been awarded two cash grants totaling $488,950 under the U.S. Internal Revenue Service's Qualifying Therapeutic Discovery Project (QTDP) program designed to support biomedical research by firms with fewer than 250 employees.

11 Nov 2010

Think treatments for cancer, diabetes don't grow on trees? Think again

Supported by thousands of years of use, a new wave of polymolecular botanical drugs (PBDs), backed by strong biomedical research and clinical trials, are growing in acceptance as a viable new drug category for the treatment and prevention of a wide spectrum of diseases from cancer to obesity.

11 Nov 2010

70% of Quebecers gamble

The initial findings of a survey on the prevalence of gambling in Quebec have been released. The study also deals with behavior problems associated with gambling. The study reveals that nearly 70 percent of Quebec adults report having bet or spent money on gambling during the previous 12 months. It also found Quebecers spend an average of $483 annually on gambling activities.

11 Nov 2010

Students perceive beer cans packaged and displayed in university colors as less dangerous

Underage and heavy drinking on college campuses continue to be issues for college administrators. While some campuses, such as the University of Missouri, have made strides in efforts to reduce heavy drinking on campus, administrators are continually trying to educate students about the risks of excessive drinking. Now, two MU psychologists have found that students who viewed images of beer cans packaged and displayed in university colors believed that drinking beer was less dangerous than those students who saw images of regular beer cans.

11 Nov 2010

Terahertz waves can manipulate network of molecules

As if borrowing from a scene in a science fiction movie, researchers at Kyoto University have successfully developed a kind of tractor beam that can be used to manipulate the network of the molecules. In a paper soon to be published in Physical Review Letters, the team has demonstrated a technique using terahertz pulses that could have broad applications in the chemical and pharmaceutical industries.

11 Nov 2010

Performance in a coalition depends on genes

How well a person performs in a coalition is partly hereditary, according to a recent study.

11 Nov 2010

BioWorld Today features ImmunGene's pipeline of next generation armed antibodies for cancer

ImmunGene, Inc., a privately held drug development company focused on targeted antibody therapeutics with numerous anti-cancer functions built into a single therapy, announced today that a profile of the company and its pipeline is featured in the November 21 issue of BioWorld Today in the NewCo section.

11 Nov 2010

World's largest data base on protein motions

After four years of conducting intensive calculations in the supercomputer MareNostrum at the Barcelona Supercomputing Center, scientists headed by Modesto Orozco at the Institute for Research in Biomedicine (IRB Barcelona) have presented the world's largest data base on protein motions. Called MoDEL, this new database holds more than 1,700 proteins and is partially accessible through Internet to researchers worldwide. MoDEL has been developed to study the basic biology of proteins and to accelerate and facilitate the design of new pharmaceutical agents.

11 Nov 2010

Neural learning appears to be independent of conscious visual processing

A team of researchers from the University of Minnesota's College of Liberal Arts and College of Science and Engineering have found that an early part of the brain's visual system rewires itself when people are trained to perceive patterns, and have shown for the first time that this neural learning appears to be independent of higher order conscious visual processing.

11 Nov 2010

Neuron subtypes control level of fear output from amygdala

The eerie music in the movie theater swells; the roller coaster crests and begins its descent; something goes bump in the night. Suddenly, you're scared: your heart thumps, your stomach clenches, your throat tightens, your muscles freeze you in place. But fear doesn't come from your heart, your stomach, your throat, or your muscles. Fear begins in your brain, and it is there specifically in an almond shaped structure called the amygdala that it is controlled, processed, and let out of the gate to kick off the rest of the fear response.

11 Nov 2010

Novel mechanism regulating circadian rhythm identified

Scientists from the Florida campus of The Scripps Research Institute have identified for the first time a novel mechanism that regulates circadian rhythm, the master clock that controls the body's natural 24-hour physiological cycle. These new findings could provide a new target not only for jet lag, shift work, and sleep disturbances, but also for disorders that result from circadian rhythm disruption, including diabetes and obesity as well as some types of cancer.

11 Nov 2010

Neurons recycle protein components for neurotransmitter release

Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, neuroscientists at the Max Planck Institute of Experimental Medicine in G-ttingen have now discovered that neurons systematically recycle the protein components necessary for transmitter release and in this way guarantee the reliability of signal transmission in the brain.

11 Nov 2010

German Genetic Diagnostics Act in need of amendment

Many aspects of the German Genetic Diagnostics Act (Gendiagnostikgesetz) are out of touch with the latest technology, almost impossible to implement in clinical practice, or even detrimental to the success of recognised screening tests, such as newborn screening. The Act, which came into force in February 2010, is in desperate need of amendment.

11 Nov 2010