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Researchers identify oncoprotein that allows MCV virus to trigger Merkel Cell Carcinoma

Researchers at the University of Pittsburgh Cancer Institute (UPCI) have identified the oncoprotein that allows a common and usually harmless virus to transform healthy cells into a rare but deadly skin cancer called Merkel Cell Carcinoma.

16 Aug 2011

Customized computer models may identify patients at risk of Lynch syndrome

People who are at risk for a certain form of colon and other types of cancer may soon have a better chance at surviving or even avoiding the diseases, thanks to a new study done by the Intermountain Clinical Genetics Institute at LDS Hospital.

16 Aug 2011

Scientists identify potential new target for childhood eye tumor

A research team led by St. Jude Children's Research Hospital scientists has identified a potential new target for treatment of the childhood eye tumor retinoblastoma.

16 Aug 2011

Tel Aviv University scientists work to determine how H1N1 becomes pandemic

The last century has seen two major pandemics caused by the H1N1 virus - the Spanish Flu in 1918 and 2009's Swine Flu scare, which had thousands travelling with surgical masks and clamoring for vaccination. But scientists did not know what distinguished the Swine Flu from ordinary influenza in pigs or seasonal outbreaks in humans, giving it the power to travel extensively and infect large populations.

16 Aug 2011

Combination immunotherapy more effective for patients with Sezary Syndrome

A three-pronged immunotherapy approach nearly doubles five-year survival among patients with rare leukemic form of cutaneous T-cell lymphoma, reports a new study by dermatologists from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2011

Novel assay can accurately detect prostate cancer than traditional screening

new prostate screening test developed by AnalizaDx, Inc., a Cleveland-based biotech company, and studied by researchers at the Seidman Cancer Center at University Hospitals (UH) Case Medical Center along with colleagues at the Cleveland Clinic, the Veterans Administration Boston Healthcare and the National Cancer Institute, may prove to be a promising new tool in the diagnosis of prostate cancer.

16 Aug 2011

Caffeine might help prevent skin cancer

A new Rutgers study strengthens the theory that caffeine guards against certain skin cancers at the molecular level by inhibiting a protein enzyme in the skin, known as ATR. Scientists believe that based on what they have learned studying mice, caffeine applied directly to the skin might help prevent damaging UV light from causing skin cancer.

16 Aug 2011

NK cells may help limit metastasis in women with breast cancer

The main cause of death in women with breast cancer is spread of the original tumor to distant sites, a process known as metastasis. Immune cells known as NK cells help limit tumor progression and metastasis in animal models.

16 Aug 2011

New pathway for type 2 diabetes

Newly diagnosed type 2 diabetics tend to have one thing in common: obesity. Exactly how diet and obesity trigger diabetes has long been the subject of intense scientific research.

16 Aug 2011

Research: Decoding infidelity may increase risk of type 2 diabetes

Type 2 diabetes is an extremely common chronic condition characterized by high levels of sugar in the blood as a result of either insufficient production of the hormone insulin or an inability of cells to respond to insulin.

16 Aug 2011

New role for harmonin protein in Usher syndrome

University of Iowa scientists have discovered a new role for a protein that is mutated in Usher syndrome, one of the most common forms of deaf-blindness in humans. The findings, which were published Aug. 8 in Nature Neuroscience, may help explain why this mutation causes the most severe form of the condition.

16 Aug 2011

Alpha-synuclein protein key to Parkinson's has likely been mischaracterized

A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach.

16 Aug 2011

Fresh food for years with newly discovered natural preservative

Scientists have discovered a natural preservative capable of destroying a whole class of bacteria, including E.coli and listeria and now food can be made to remain fresh and last for years. There would also be no need to refrigerate produce treated with the preservative, called, bisin, which is produced by harmless bacteria.

15 Aug 2011

Episodic memory depends on the hippocampus

Memory is not a single process but is made up of several sub-processes relying on different areas of the brain. Episodic memory, the ability to remember specific events such as what you did yesterday, is known to be vulnerable to brain damage involving the hippocampus. The question is, what happens when damage to the hippocampus occurs very early in life?

12 Aug 2011

Plant scientists reveal genetic mechanism that enables viral organisms to cause diseases

CSIRO plant scientists have shed light on a problem that has puzzled researchers since the first virus was discovered in 1892 - how exactly do they cause disease? In a major breakthrough that helps us better understand how viruses cause diseases in plants - and potentially in animals and humans - Dr Ming-Bo Wang and Neil Smith of CSIRO Plant Industry have revealed a genetic mechanism that enables viral organisms to infect hosts and cause diseases.

12 Aug 2011

Targeted therapies that attack stem cell-like cancer cells can prevent spread of prostate cancer

A successful interdisciplinary project is underway between two research groups, in which senior researcher Rebecka Hellsten and Professor Anders Bjartell at the Faculty of Medicine's division for Urological Cancer Research, Sk-ne University Hospital in Malm-, and Professor Olov Sterner and Assistant Professor Martin Johansson at the Lund University division of Organic Chemistry recently published their latest research findings in the scientific online journal PLoS ONE.

12 Aug 2011

More biodiversity needed to keep ecosystems functioning

The biological diversity of organisms on earth is not just something we enjoy when taking a walk through a blossoming meadow in spring; it is also the basis for countless products and services provided by nature, including food, building materials, and medicines as well as the self-purifying qualities of water and protection against erosion.

12 Aug 2011

Fibrate drugs may not prevent heart attacks in diabetes patients with elevated cholesterol

Type 2 diabetes patients, who face higher risk of cardiovascular disease, often take a combination of medications designed to lower their LDL or "bad" cholesterol and triglyceride levels while raising their HDL or "good" cholesterol because doctors long have thought that taken together, the drugs offer protection from heart attacks and improve survival.

12 Aug 2011

Benefits of nanoparticle sunscreens outweigh risks

The most personal encounter that many consumers have had so far with the much-heralded field of nanotechnology is the topic of an article in the current edition of Chemical & Engineering News (C&EN), the American Chemical Society's weekly newsmagazine.

12 Aug 2011

Metabolic profile reveals need for gender-specific therapies

Analyses of the metabolic profile of blood serum reveal significant differences between men and women. From their tests, scientists at the Helmholtz Zentrum München have concluded that there is a need for gender-specific therapies. The study was financed by the German Centre for Diabetes Research and was published in the current edition of the internationally renowned peer-reviewjournal PLoS Genetics.

12 Aug 2011