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Each melanoma cell capable of cancer stem cell behavior: Study

Scientists at The Wistar Institute offer a new explanation for the persistent ability of melanoma cells to self-renew, one of the reasons why melanoma remains the deadliest form of skin cancer. The concept of the "dynamic stemness" of melanoma can explain why melanoma cells behave like both conventional tumor cells and cancer stem cells.

14 May 2010

ISCA recommends chromosomal microarray as new standard for genetic evaluation of children

An international consortium of genetics experts has issued a consensus statement recommending chromosomal microarray (CMA) as the new standard practice for genetic evaluation of children with unexplained developmental delay, autism or birth defects.

14 May 2010

GRNCM1 do not cause cardiac arrhythmias after transplantation: Preclinical study

Geron Corporation today reported positive preclinical study data showing that GRNCM1, Geron's cardiomyocyte product derived from human embryonic stem cells, does not cause cardiac arrhythmias after transplantation into a model of chronic heart damage designed to test this potential safety concern.

14 May 2010

Mild-mannered organelles can detect virus invasion signals: Researchers

Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch. The findings mean scientists must rethink the design of antiviral immunity and how the body fends off viruses of all types, including influenza and HIV.

14 May 2010

GE Healthymagination Fund invests $5M in CardioDx

GE Healthcare, the healthcare business of GE and CardioDx, a pioneer in cardiovascular genomic diagnostics, announced today that the companies have entered into a strategic alliance to advance and co-develop diagnostic technologies to improve the care and management of patients with cardiovascular disease.

14 May 2010

Fibrocell Science commences histology study of azficel-T for treatment of nasolabial fold wrinkles

Fibrocell Science, Inc., a biotechnology company focused on the development of autologous cell therapies for aesthetic, medical and scientific applications, announced the initiation of a small histology study (IT-H-001) of azficel-T, an autologous cell therapy currently under review by the U.S. Food and Drug Administration (FDA) for the treatment of moderate to severe nasolabial fold wrinkles.

14 May 2010

Calcium deficiency may make people more prone to osteoporosis, obesity in later life: Study

There's no denying that people need calcium for strong, healthy bones. But new research from North Carolina State University suggests that not getting enough calcium in the earliest days of life could have a more profound, lifelong impact on bone health and perhaps even obesity than previously thought.

14 May 2010

Arrowhead decreases second-quarter consolidated operating expenses by 58%

Arrowhead Research Corporation today announced financial results for its fiscal 2010 second quarter ended March 31, 2010.

13 May 2010

Researchers provide better understanding of anti-cell death proteins and potential antagonist to defeat them

Cancer uses devious means to evade treatment and survive. One prime example is the way tumors express anti-cell death (anti-apoptotic) proteins to resist chemotherapy and radiation. However, the Pellecchia laboratory at Sanford-Burnham Medical Research Institute has made two recent discoveries that may help curb these anti-apoptotic proteins and make current treatments more effective.

13 May 2010

CyGene Laboratories reports heightened interest in at-home genetic testing

CyGene Laboratories Inc. today announced that it has experienced unprecedented levels of interest and requests for information following recent media coverage of Walgreens' decision to offer genetics testing kits supplied by Pathway Genomics in certain of their retail stores.

13 May 2010

Study shows direct cellular interaction between endocannabinoids and alcohol in the brain

In findings that should finally put to rest a decade of controversy in the field of neurobiology, a team at The Scripps Research Institute has found decisive evidence that a specific neurotransmitter system-the endocannabinoid system-is active in a brain region known to play a key role in the processing of memory, emotional reactions, and addiction formation. The new study also shows that this system can dampen the effects of alcohol, suggesting an avenue for the development of drugs to combat alcohol addiction.

13 May 2010

Daily consumption of probiotic cheese helps tackle age-related changes in immune system: Research

Scientists in Finland have discovered that cheese can help preserve and enhance the immune system of the elderly by acting as a carrier for probiotic bacteria. The research, published in FEMS Immunology & Medical Microbiology, reveals that daily consumption of probiotic cheese helps to tackle age-related changes in the immune system.

13 May 2010

Research article focuses on how IECs respond to probiotic strain B. lactis HN019

Probiotics are a group of live microorganisms administered in adequate amounts which confer a beneficial health effect on the host. This bacterial community plays a pivotal role in human nutrition and health by promoting the supply of nutrients, preventing pathogen colonization and shaping and maintaining normal mucosal immunity.

13 May 2010

SAGE launches further two Therapeutic Advances journals

SAGE has extended its suite of Therapeutic Advances journals with the launch of a further two titles: Therapeutic Advances in Chronic Disease and Therapeutic Advances in Endocrinology and Metabolism.

13 May 2010

Research investigates MDR in human HCC

Hepatocellular carcinoma responds poorly to chemotherapy owing to MDR. Recent studies have shown the tumors derived from the colon, kidney, or adrenal cortex, and HCC exhibited overexpression of MDR1/P-gp. This overexpression results in a primary MDR phenotype of these cancers.

13 May 2010

Cognitive strategies lessen depression symptoms: Study

Moderate to severely depressed clients showed greater improvement in cognitive therapy when therapists emphasized changing how they think rather than how they behave, new research has found.

13 May 2010

Researchers to discuss various implications for personalized medicine during one-day symposium

On May 27, researchers with the National Human Genome Research Institute and the National Cancer Institute, along with Group Health Cooperative in Seattle and Henry Ford Health System, will debate and discuss that question during the one-day symposium "Multiplex Initiative: Implications for Personalized Medicine."

13 May 2010

Celera to present on AIDS pandemic, AZT drugs at Computational Molecular Biology Symposium

In 1985 there was little hope for people with AIDS. Newspapers and television screens were filled with ghastly pictures of emaciated figures dying from a disease that had no cure.

13 May 2010

RYGB surgery increases insulin activity in diabetes mellitus patients

Diabetes mellitus is a chronic metabolic disease resulted from, either decreased production of insulin or increased resistance to it from peripheral tissues or both factors combined together. While medical treatment remains the mainstay of treatment for diabetes, some surgical procedures, such as Roux-en-Y gastric bypass, have demonstrated some potential to be a treatment option for diabetes.

13 May 2010

Researchers develop new approach to immunotherapy of cancer

Harnessing the immune system is emerging as one of the most promising new ways to fight cancer. Most cancer cells are eliminated by the immune system; however, over a lifetime, a few may escape this immune surveillance and lead to tumors and metastases. Hence a formidable opportunity has been to find ways to make the immune system recognize the tumor as a foreign body and trigger a response.

13 May 2010

Medical Science News

Each melanoma cell capable of cancer stem cell behavior: Study

ISCA recommends chromosomal microarray as new standard for genetic evaluation of children

GRNCM1 do not cause cardiac arrhythmias after transplantation: Preclinical study

Mild-mannered organelles can detect virus invasion signals: Researchers

GE Healthymagination Fund invests $5M in CardioDx

Fibrocell Science commences histology study of azficel-T for treatment of nasolabial fold wrinkles

Calcium deficiency may make people more prone to osteoporosis, obesity in later life: Study

Arrowhead decreases second-quarter consolidated operating expenses by 58%

Researchers provide better understanding of anti-cell death proteins and potential antagonist to defeat them

CyGene Laboratories reports heightened interest in at-home genetic testing

Study shows direct cellular interaction between endocannabinoids and alcohol in the brain

Daily consumption of probiotic cheese helps tackle age-related changes in immune system: Research

Research article focuses on how IECs respond to probiotic strain B. lactis HN019

SAGE launches further two Therapeutic Advances journals

Research investigates MDR in human HCC

Cognitive strategies lessen depression symptoms: Study

Researchers to discuss various implications for personalized medicine during one-day symposium

Celera to present on AIDS pandemic, AZT drugs at Computational Molecular Biology Symposium

RYGB surgery increases insulin activity in diabetes mellitus patients

Researchers develop new approach to immunotherapy of cancer

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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